• ASIC3 9311 Druggable Genome

    Alternate Names:

    9311
    ACID SENSING ION CHANNEL SUBUNIT 3
    ASIC3
    ACCN3
    DRASIC
    SLNAC1
    TNaC1
    611741
    101
    ENSG00000213199
    OTTHUMG00000158685
    BE0004768
    Q9UHC3
    686
    acid-sensing (proton-gated) ion channel 3
    ASIC3_HUMAN
    ACID-SENSING ION CHANNEL 3

    Gene Info:

    GuideToPharmacology Gene Category Name Acid-sensing (proton-gated) ion channels (ASICs)
    GuideToPharmacology Gene Category ID 118
    GuideToPharmacology Gene Type lgic
    Target Class transporter
    Target Subclass TC:1.A.6.1.2
    Gene Biotype PROTEIN_CODING"
    Interpro Name Na+ channel, amiloride-sensitive
    Human Readable Name ION CHANNEL
    Interpro Acc IPR001873
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Short Name Na+channel_ASC
    (4 More Sources)
  • Interaction Types:
    activator

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction at pH 7.4
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    activator

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction largly non-desensitizing; at pH 7.4
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    activator

    Interaction Info:
    Interaction Context Extracellular
    Specific Action of the Ligand None
    Details of Interaction transient component

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction transient component only - sustained component enhanced by 200μM amiloride at pH 4
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction sustained component
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction sustained component
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction transient component
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction sustained component
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist
    activator

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction at pH 7.4
    Endogenous Drug? False

    • Version: 90_38

    Alternate Names:
    ASIC3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING"

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ACID-SENSING ION CHANNEL 3 Uniprot Protein Name
    ASIC3_HUMAN Uniprot Id
    ENSG00000213199 Ensembl Gene Id

    Gene Info:
    Interpro Name Na+ channel, amiloride-sensitive
    Human Readable Name ION CHANNEL
    Interpro Acc IPR001873

    Publications:

    • Version: 4-March-2015

    Alternate Names:
    acid-sensing (proton-gated) ion channel 3 HUGO Gene Name
    101 HUGO Gene ID
    ASIC3 Gene Symbol

    Gene Info:
    GuideToPharmacology Gene Category Name Acid-sensing (proton-gated) ion channels (ASICs)
    GuideToPharmacology Gene Category ID 118
    GuideToPharmacology Gene Type lgic

    Publications:

    • Version: January-2014

    Alternate Names:
    ACCN3 Gene Symbol

    Gene Info:
    Target Class transporter
    Target Subclass TC:1.A.6.1.2

    Publications:

    • Version: 5.0.8

    Alternate Names:
    ASIC3 DrugBank Gene Name
    Q9UHC3 UniProt Accession
    9311 Entrez Gene Id

    Gene Info:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000213199 Gene Symbol
    ASIC3 Ensembl Id

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    Q9UHC3 UniProtKB ID
    ASIC3_HUMAN GO Gene Synonym
    ACCN3 GO Gene Synonym

    Gene Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    ASIC3 GuideToPharmacology Name
    Q9UHC3 UniProtKB ID

    Gene Info:

    Publications: