DGIdb - APRT Gene Record

APRT 353 Druggable Genome

Alternate Names:

353
ADENINE PHOSPHORIBOSYLTRANSFERASE
APRT
AMP
APRTD
102600
626
ENSG00000198931
OTTHUMG00000175454
BE0000115
P07741
APT_HUMAN
ADENINE PHOSPHORIBOSYLTRANSFERASE (EC 2.4.2.7) (APRT). [SOURCE:UNIPROT/SWISSPROT;ACC:P07741]

Gene Info:

Gene Biotype	PROTEIN_CODING"
Uniprot Evidence	1: Evidence at protein level
Human Readable Name	DRUGGABLE GENOME
Interpro Acc	IPR000836
Uniprot Status	Swiss-Prot
Interpro Short Name	PRibTrfase
Interpro Type	Domain
Interpro Name	Phosphoribosyltransferase

(1 More Sources)

Publications:

Di Pietro et al., 2007, Clinical, biochemical and molecular diagnosis of a compound homozygote for the 254 bp deletion-8 bp insertion of the APRT gene suffering from severe renal failure., Clin. Biochem.
Barrett et al., 2006, Configuration of a scintillation proximity assay for the activity assessment of recombinant human adenine phosphoribosyltransferase., Assay Drug Dev Technol
Katahira et al., 2006, Role of adenosine salvage in wound-induced adenylate biosynthesis in potato tuber slices., Plant Physiol. Biochem.
Katahira et al., 2006, Profiles of purine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers., Planta
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Boitz et al., 2006, Leishmania donovani singly deficient in HGPRT, APRT or XPRT are viable in vitro and within mammalian macrophages., Mol. Biochem. Parasitol.
Turker et al., 1999, A novel signature mutation for oxidative damage resembles a mutational pattern found commonly in human cancers., Cancer Res.
Thompson et al., 1980, Failure of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate to enhance sister chromatid exchange, mitotic segregation, or expression of mutations in Chinese hamster cells., Cancer Res.

ADENINE APRT

Interaction Types:

n/a

Interaction Info:

Publications:

Di Pietro et al., 2007, Clinical, biochemical and molecular diagnosis of a compound homozygote for the 254 bp deletion-8 bp insertion of the APRT gene suffering from severe renal failure., Clin. Biochem.

Barrett et al., 2006, Configuration of a scintillation proximity assay for the activity assessment of recombinant human adenine phosphoribosyltransferase., Assay Drug Dev Technol

Katahira et al., 2006, Role of adenosine salvage in wound-induced adenylate biosynthesis in potato tuber slices., Plant Physiol. Biochem.

PHOSPHORIBOSYL PYROPHOSPHATE APRT

Interaction Types:

n/a

Interaction Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
CHEMBL1163018 APRT

Interaction Types:

n/a

Interaction Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
CITRIC ACID APRT

Interaction Types:

n/a

Interaction Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
HYDROGEN PEROXIDE APRT

Interaction Types:

n/a

Interaction Info:

Publications:

Turker et al., 1999, A novel signature mutation for oxidative damage resembles a mutational pattern found commonly in human cancers., Cancer Res.

PHORBOL MYRISTATE ACETATE APRT

Interaction Types:

n/a

Interaction Info:

Publications:

Thompson et al., 1980, Failure of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate to enhance sister chromatid exchange, mitotic segregation, or expression of mutations in Chinese hamster cells., Cancer Res.

Ensembl: ENSG00000198931
- Version: 90_38
Alternate Names:

APRT Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING"

Publications:
RussLampel: ENSG00000198931
- Version: 26-July-2011
Alternate Names:

ADENINE PHOSPHORIBOSYLTRANSFERASE (EC 2.4.2.7) (APRT). [SOURCE:UNIPROT/SWISSPROT;ACC:P07741] Description

ENSG00000198931 Ensembl Gene Id

APRT Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Publications:
HopkinsGroom: P07741
- Version: 11-September-2012
Alternate Names:

APRT Uniprot Gene Name

353 Entrez Gene Id

P07741 Uniprot Accession

Gene Info:

Uniprot Evidence 1: Evidence at protein level

Human Readable Name DRUGGABLE GENOME

Interpro Acc IPR000836

Publications:

DrugBank: BE0000115

Version: 5.0.8

Alternate Names:

APRT DrugBank Gene Name

P07741 UniProt Accession

353 Entrez Gene Id

Gene Info:

Publications:

Di Pietro et al., 2007, Clinical, biochemical and molecular diagnosis of a compound homozygote for the 254 bp deletion-8 bp insertion of the APRT gene suffering from severe renal failure., Clin. Biochem.

Barrett et al., 2006, Configuration of a scintillation proximity assay for the activity assessment of recombinant human adenine phosphoribosyltransferase., Assay Drug Dev Technol

Katahira et al., 2006, Role of adenosine salvage in wound-induced adenylate biosynthesis in potato tuber slices., Plant Physiol. Biochem.

NCI: APRT

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Turker et al., 1999, A novel signature mutation for oxidative damage resembles a mutational pattern found commonly in human cancers., Cancer Res.

Thompson et al., 1980, Failure of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate to enhance sister chromatid exchange, mitotic segregation, or expression of mutations in Chinese hamster cells., Cancer Res.

ADENINE PHOSPHORIBOSYLTRANSFERASE (EC 2.4.2.7) (APRT). [SOURCE:UNIPROT/SWISSPROT;ACC:P07741]	Description
ENSG00000198931	Ensembl Gene Id
APRT	Display Id

APRT	Uniprot Gene Name
353	Entrez Gene Id
P07741	Uniprot Accession

APRT	DrugBank Gene Name
P07741	UniProt Accession
353	Entrez Gene Id

APRT Gene Record

APRT 353 Druggable Genome

Alternate Names:

Gene Info:

Publications:

ADENINE APRT

Interaction Types: n/a

Interaction Info:

PHOSPHORIBOSYL PYROPHOSPHATE APRT

Interaction Types: n/a

Interaction Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

CHEMBL1163018 APRT

Interaction Types: n/a

Interaction Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

CITRIC ACID APRT

Interaction Types: n/a

Interaction Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

HYDROGEN PEROXIDE APRT

Interaction Types: n/a

Interaction Info:

Publications: Turker et al., 1999, A novel signature mutation for oxidative damage resembles a mutational pattern found commonly in human cancers., Cancer Res.

PHORBOL MYRISTATE ACETATE APRT

Interaction Types: n/a

Interaction Info:

Publications: Thompson et al., 1980, Failure of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate to enhance sister chromatid exchange, mitotic segregation, or expression of mutations in Chinese hamster cells., Cancer Res.

Ensembl: ENSG00000198931

Alternate Names: APRT Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING"

Publications:

RussLampel: ENSG00000198931

Alternate Names: ADENINE PHOSPHORIBOSYLTRANSFERASE (EC 2.4.2.7) (APRT). [SOURCE:UNIPROT/SWISSPROT;ACC:P07741] Description ENSG00000198931 Ensembl Gene Id APRT Display Id

Gene Info: Human Readable Name DRUGGABLE GENOME

Publications:

HopkinsGroom: P07741

Alternate Names: APRT Uniprot Gene Name 353 Entrez Gene Id P07741 Uniprot Accession

Gene Info: Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME Interpro Acc IPR000836

Publications:

DrugBank: BE0000115

Alternate Names: APRT DrugBank Gene Name P07741 UniProt Accession 353 Entrez Gene Id

Gene Info:

NCI: APRT

Alternate Names:

Gene Info:

Interaction Types:

n/a

Interaction Types:

n/a

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Interaction Types:

n/a

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Interaction Types:

n/a

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Interaction Types:

n/a

Publications:

Turker et al., 1999, A novel signature mutation for oxidative damage resembles a mutational pattern found commonly in human cancers., Cancer Res.

Interaction Types:

n/a

Publications:

Thompson et al., 1980, Failure of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate to enhance sister chromatid exchange, mitotic segregation, or expression of mutations in Chinese hamster cells., Cancer Res.

Alternate Names:

APRT Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING"

Alternate Names:

ADENINE PHOSPHORIBOSYLTRANSFERASE (EC 2.4.2.7) (APRT). [SOURCE:UNIPROT/SWISSPROT;ACC:P07741] Description

ENSG00000198931 Ensembl Gene Id

APRT Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Alternate Names:

APRT Uniprot Gene Name

353 Entrez Gene Id

P07741 Uniprot Accession

Gene Info:

Uniprot Evidence 1: Evidence at protein level

Human Readable Name DRUGGABLE GENOME

Interpro Acc IPR000836

Alternate Names:

APRT DrugBank Gene Name

P07741 UniProt Accession

353 Entrez Gene Id