DGIdb - AHCY Gene Record

AHCY 191 Druggable Genome

Alternate Names:

191
ADENOSYLHOMOCYSTEINASE
AHCY
SAHH
adoHcyase
180960
343
ENSG00000101444
OTTHUMG00000140098
NM_153839
G protein-coupled receptor 111
18991
222611
Q8IZF7
NP_722581
GPR111
<i>GPR111</i>
PROBABLE G-PROTEIN COUPLED RECEPTOR 111
GP111_HUMAN
ENSG00000164393
ADENOSYLHOMOCYSTEINASE (EC 3.3.1.1) (S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE) (ADOHCYASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P23526]
BE0001684
P23526
SAHH_HUMAN
1233
S-Adenosylhomocysteine hydrolase

Gene Info:

GuideToPharmacology Gene Category Name	Adhesion Class GPCRs
GuideToPharmacology Gene Category ID	17
GuideToPharmacology Gene Type	gpcr
Interpro Acc	IPR000832
Interpro Name	GPCR, family 2, secretin-like
Human Readable Name	DRUGGABLE GENOME
Interpro Type	Family
Uniprot Evidence	2: Evidence at transcript level
Uniprot Status	Swiss-Prot
Interpro Short Name	GPCR_2_secretin-like
Human Readable Name	G PROTEIN COUPLED RECEPTOR
Interpro Short Name	Adenosylhomocysteinase
Uniprot Evidence	1: Evidence at protein level
Interpro Acc	IPR000043
Interpro Name	Adenosylhomocysteinase
Gene Biotype	PROTEIN_CODING"

(4 More Sources)

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

CHEMBL202701 AHCY

Interaction Types:

inhibitor

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Publications:

ERITADENINE AHCY

Interaction Types:

n/a

Interaction Info:

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Ensembl: ENSG00000101444
- Version: 90_38
Alternate Names:

AHCY Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING"

Publications:
GuideToPharmacologyGenes: 191
- Version: 4-March-2015
Alternate Names:

G protein-coupled receptor 111 HUGO Gene Name

18991 HUGO Gene ID

GPR111 Gene Symbol

Gene Info:

GuideToPharmacology Gene Category Name Adhesion Class GPCRs

GuideToPharmacology Gene Category ID 17

GuideToPharmacology Gene Type gpcr

Publications:
HopkinsGroom: Q8IZF7
- Version: 11-September-2012
Alternate Names:

GP111_HUMAN Uniprot Id

Q8IZF7 Uniprot Accession

GPR111 Uniprot Gene Name

Gene Info:

Interpro Acc IPR000832

Interpro Name GPCR, family 2, secretin-like

Human Readable Name DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000101444

Version: 26-July-2011

Alternate Names:

AHCY Display Id

ENSG00000101444 Ensembl Gene Id

ADENOSYLHOMOCYSTEINASE (EC 3.3.1.1) (S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE) (ADOHCYASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P23526] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Publications:

HopkinsGroom: P23526
- Version: 11-September-2012
Alternate Names:

P23526 Uniprot Accession

AHCY Uniprot Gene Name

ENSG00000101444 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Interpro Type Family

Interpro Short Name Adenosylhomocysteinase

Publications:

DrugBank: BE0001684

Version: 5.0.8

Alternate Names:

AHCY DrugBank Gene Name

P23526 UniProt Accession

191 Entrez Gene Id

Gene Info:

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

GuideToPharmacologyInteractions: 1233
- Version: 27-September-2017
Alternate Names:

S-Adenosylhomocysteine hydrolase GuideToPharmacology Name

P23526 UniProtKB ID

Gene Info:

Publications:
HingoraniCasas: ENSG00000101444
- Version: 31-May-2017
Alternate Names:

ENSG00000101444 Gene Symbol

AHCY Ensembl Id

Gene Info:

Publications:

Specific Action of the Ligand	Inhibition
Endogenous Drug?	False

G protein-coupled receptor 111	HUGO Gene Name
18991	HUGO Gene ID
GPR111	Gene Symbol

GP111_HUMAN	Uniprot Id
Q8IZF7	Uniprot Accession
GPR111	Uniprot Gene Name

AHCY	Display Id
ENSG00000101444	Ensembl Gene Id
ADENOSYLHOMOCYSTEINASE (EC 3.3.1.1) (S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE) (ADOHCYASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P23526]	Description

AHCY	DrugBank Gene Name
P23526	UniProt Accession
191	Entrez Gene Id

S-Adenosylhomocysteine hydrolase	GuideToPharmacology Name
P23526	UniProtKB ID

AHCY Gene Record

AHCY 191 Druggable Genome

Alternate Names:

Gene Info:

Publications:

CHEMBL202701 AHCY

Interaction Types: inhibitor

Interaction Info: Specific Action of the Ligand Inhibition Endogenous Drug? False

Publications:

ERITADENINE AHCY

Interaction Types: n/a

Interaction Info:

Publications: Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Ensembl: ENSG00000101444

Alternate Names: AHCY Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING"

Publications:

GuideToPharmacologyGenes: 191

Alternate Names: G protein-coupled receptor 111 HUGO Gene Name 18991 HUGO Gene ID GPR111 Gene Symbol

Gene Info: GuideToPharmacology Gene Category Name Adhesion Class GPCRs GuideToPharmacology Gene Category ID 17 GuideToPharmacology Gene Type gpcr

Publications:

HopkinsGroom: Q8IZF7

Alternate Names: GP111_HUMAN Uniprot Id Q8IZF7 Uniprot Accession GPR111 Uniprot Gene Name

Gene Info: Interpro Acc IPR000832 Interpro Name GPCR, family 2, secretin-like Human Readable Name DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000101444

Alternate Names: AHCY Display Id ENSG00000101444 Ensembl Gene Id ADENOSYLHOMOCYSTEINASE (EC 3.3.1.1) (S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE) (ADOHCYASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P23526] Description

Gene Info: Human Readable Name DRUGGABLE GENOME

Publications:

HopkinsGroom: P23526

Alternate Names: P23526 Uniprot Accession AHCY Uniprot Gene Name ENSG00000101444 Ensembl Gene Id

Gene Info: Human Readable Name DRUGGABLE GENOME Interpro Type Family Interpro Short Name Adenosylhomocysteinase

Publications:

DrugBank: BE0001684

Alternate Names: AHCY DrugBank Gene Name P23526 UniProt Accession 191 Entrez Gene Id

Gene Info:

Publications: Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

GuideToPharmacologyInteractions: 1233

Alternate Names: S-Adenosylhomocysteine hydrolase GuideToPharmacology Name P23526 UniProtKB ID

Gene Info:

Publications:

HingoraniCasas: ENSG00000101444

Alternate Names: ENSG00000101444 Gene Symbol AHCY Ensembl Id

Gene Info:

Publications:

Interaction Types:

inhibitor

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Interaction Types:

n/a

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Alternate Names:

AHCY Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING"

Alternate Names:

G protein-coupled receptor 111 HUGO Gene Name

18991 HUGO Gene ID

GPR111 Gene Symbol

Gene Info:

GuideToPharmacology Gene Category Name Adhesion Class GPCRs

GuideToPharmacology Gene Category ID 17

GuideToPharmacology Gene Type gpcr

Alternate Names:

GP111_HUMAN Uniprot Id

Q8IZF7 Uniprot Accession

GPR111 Uniprot Gene Name

Gene Info:

Interpro Acc IPR000832

Interpro Name GPCR, family 2, secretin-like

Human Readable Name DRUGGABLE GENOME

Alternate Names:

AHCY Display Id

ENSG00000101444 Ensembl Gene Id

ADENOSYLHOMOCYSTEINASE (EC 3.3.1.1) (S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE) (ADOHCYASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P23526] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Alternate Names:

P23526 Uniprot Accession

AHCY Uniprot Gene Name

ENSG00000101444 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Interpro Type Family

Interpro Short Name Adenosylhomocysteinase

Alternate Names:

AHCY DrugBank Gene Name

P23526 UniProt Accession

191 Entrez Gene Id

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Alternate Names:

S-Adenosylhomocysteine hydrolase GuideToPharmacology Name

P23526 UniProtKB ID

Alternate Names:

ENSG00000101444 Gene Symbol

AHCY Ensembl Id