• XL-228 CHEMBL3545085 Antineoplastic

    Alternate Names:

    XL-228
    XL228
    DB05184
    4-N-(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)-6-(4-METHYLPIPERAZIN-1-YL)-2-N-[(3-PROPAN-2-YL-1,2-OXAZOL-5-YL)METHYL]PYRIMIDINE-2,4-DIAMINE
    2,4-PYRIMIDINEDIAMINE, N(SUP 4)-(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)-N(SUP 2)-((3-(1-METHYLETHYL)-5-ISOXAZOLYL)METHYL)-6-(4-METHYL-1-PIPERAZINYL)-
    KB-303240
    HY-15749
    CS-1648
    ZINC203005669
    33M2XSK003
    AOB5553
    SCHEMBL11342904
    XL 228
    UNII-33M2XSK003
    898280-07-4
    59757974

    Drug Info:

    FDA Approval not approved
    Drug Class small molecule
    Drug Indications antineoplastic agent
    Drug Class Kinase Inhibitors
    Drug Categories N/A
    Drug Groups investigational
    Drug Type small molecule
    (2 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes
    Mechanism of Interaction Insulin-like growth factor I receptor inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes
    Trial Name XL228
    Novel drug target Established target

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Trial Name XL228
    Novel drug target Established target
    Mechanism of Interaction Tyrosine-protein kinase ABL inhibitor

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name XL228
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    Publications:

    • Version: 5.0.8

    Alternate Names:
    XL228 DrugBank Drug Name

    Drug Info:
    Drug Type small molecule
    Drug Groups investigational

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    XL228 Development Name

    Drug Info:
    Drug Class Kinase Inhibitors

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antineoplastic agent
    Drug Class small molecule
    FDA Approval not approved

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    XL-228 pubchem_primary_name
    59757974 PubChem CID
    898280-07-4 Drug Synonym

    Drug Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    XL228 Primary Drug Name
    XL228 Drug Synonym

    Drug Info:

    Publications:

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications: