• TENIPOSIDE CHEMBL452231 FDA ApprovedAntineoplasticImmunotherapy

    Alternate Names:

    Teniposide
    Vumon
    VM-26
    C857
    Bang Lai
    29767-20-2
    Epidophyllotoxin
    4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside)
    DB00444
    0015-3075-19
    VEHEM
    31930
    TENIPOSIDO [INN-SPANISH]
    176397
    C11153
    588989
    D02698
    46507536
    VEHAM-SANDOZ
    TENIPOSIDUM [INN-LATIN]
    DAP000651
    34698
    VEE M-26
    PA451611
    (5S,5AR,8AR,9R)-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-8-OXO-5,5A,6,8,8A,9-HEXAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-5-YL 4,6-O-(2-THIENYLMETHYLENE)-BETA-D-GLUCOPYRANOSIDE
    (5S,5AR,8AR,9R)-5-[[(4AR,6R,7R,8R,8AS)-7,8-DIHYDROXY-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDRO-5H-[2]BENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    (5R)-5,8,8ABETA,9-TETRAHYDRO-9ALPHA-[4-O,6-O-(2-THENYLIDENE)-BETA-D-GLUCOPYRANOSYLOXY]-5BETA-(4-HYDROXY-3,5-DIMETHOXYPHENYL)FURO[3',4':6,7]NAPHTHO[2,3-D]-1,3-DIOXOL-6(5AALPHAH)-ONE
    EPIPODOPHYLLOTOXIN, 4'-DEMETHYL-, 9-(4,6-O-2-THENYLIDENE-BETA-D-GLUCOPYRANOSIDE) (8CI)
    CID6708778
    CID5284623
    NSC 12819
    CID452548
    CID275784
    CID107642
    PTG
    FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-((4,6-O-(2-THIENYLMETHYLENE)-BETA-D-GLUCOPYRANOSYL)-OXY)-, (5R-(5ALPHA,5ABETA,8AALPHA,9BETA(R*)))-
    FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-((4,6-O-((R)-2-THIENYLMETHYLENE)-BETA-D-GLUCOPYRANOSYL)OXY)-, (5R,5AR,8AR,9S)-
    (5R-(5ALPHA,5ABETA,8AALPHA,9BETA(R*)))-5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-((4-6-O-(2-THIENYLMETHYLENE)-BETA-D-GLUCOPYRANOSYL)OXY)FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE
    MOLPORT-005-940-276
    MOLPORT-003-666-525
    4'-DEMETHYL 1-O-(4,6-O,O-(2-THENYLIDENE)-BETA-D-GLUCOPYRANOSYL)EPIPODOPHYLLOTOXIN
    CID5396
    CHEBI:75988
    CHEMBL278534
    TENIPOSIDE [USAN:INN:BAN]
    SCHEMBL94844
    BRD-A35588707-001-02-2
    VUMON, VM-26, VEHEM, NSC 122819, TENIPOSIDE
    I06-2040
    4'-DEMETHYLEPIPODOPHYLLOTOXIN THENYLIDENE GLUCOSIDE
    DEMETHYL EPIPODOPHYLLOTOXIN THENYLIDINE GLUCOSIDE
    FT-0080118
    NCI60_000540
    LS-63999
    CID34698
    NSC122819
    AR-1A6526
    AR-1A6252
    AC-759
    VM 26
    TENIPOSID
    KST-1A5976
    KST-1A3576
    HMS2093O15
    HMS1922B15
    MOLPORT-006-822-656
    KBIO3_002939
    KBIO2_007165
    KBIO2_004597
    KBIO2_002029
    KBIO1_001832
    AC1L32H7
    AMBAP29767-20-2
    SPBIO_001773
    TENIPOSIDE [USAN:BAN:INN]
    SPECTRUM1504094
    DIVK1C_006888
    MLS000766234
    KBIOSS_002029
    KBIOGR_001050
    BSPBIO_003436
    NEURO_000056
    AC1NR4S8
    AC1L5IF3
    AC1L1K9H
    TENIPOSIDE (USAN/INN)
    SPECTRUM5_001111
    SPECTRUM4_000585
    SPECTRUM3_001898
    SPECTRUM2_001647
    AC1O8FOE
    AC1L9QDK
    SPECPLUS_000792
    35317-44-3
    31514-29-1
    23362-13-2
    SPECTRUM_001549
    EPIPODOPHYLLOTOXIN, 4'-DEMETHYL-, 9-(4,6-O-2-THENYLIDENE-BETA-D-GLUCOPYRANOSIDE)
    S1787_SELLECK
    VUMON (TN)
    EPIPODOPHYLLOTOXIN-BETA-D-THENYLIDENE-GLUCOSIDE, 4'-DEMETHYL-
    4'-DEMETHYLEPIPODOPHYLLOTOXIN-BETA-D-THENYLIDINE GLUCOSIDE
    4'-DIMETHYL-9-(4,6-O-2-THENYID)-EPIPODOPHYLLOTOXIN
    4'-DEMETHYLEPIPODOPHYLLOTOXIN 9-(4,6-O-2-THENYLIDENE-BETA-D-GLUCOPYRANOSIDE)
    EINECS 249-831-2
    UNII-957E6438QA
    CCRIS 2058
    AC1L1S3X
    NSC-122819
    NSC 122819
    HSDB 6546
    TENIPOSIDUM
    TENIPOSIDO
    299-36-5
    55256-09-2
    C32H32O13S
    SMR000528847
    90659141
    (5R,5AR,8AR,9S)-5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-[[4,6-O-[(R)-2-THIENYLMETHYLENE]-|A-D-GLUCOPYRANOSYL]OXY]FURO[3',4':6,7]NAPHTHO[2,3-D]-1,3-DIOXOL-6(5AH)-ONE
    S 122819
    FURO[3',7]NAPHTHO[2,3-D]-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-[[4,6-O-(2-THIENYLMETHYLENE)-.BETA.-D-GLUCOPYRANOSYL]OXY]-, [5R-[5.ALPHA.,5A.BETA.,8A.ALPHA.,9.BETA.(R*)]]-
    FURO[3',7]NAPHTHO[2,3-D]-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-[[4,6-O-(2-THIENYLMETHYLENE)-.BETA.-D-GLUCOPYRANOSYL]OXY]-, [5R-(5.ALPHA.,5A.BETA.,8A.ALPHA.,9.BETA.)]-
    EPIPODOPHYLLOTOXIN, 9-(4,6-O-2-THIENYLIDENE-.BETA.-D-GLUCOPYRANOSIDE)
    EPIPODOPHYLLOTOXIN, 9-(4,6-O-2-THENYLIDENE-.BETA.-D-GLUCOPYRANOSIDE)
    AB01273974-01
    CHEMBL2003481
    VUMON (BRISTOL MEYERS)
    54610154
    (5S,5AR,8AR,9R)-5-[[(4AR,7R,8R,8AS)-7,8-DIHYDROXY-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDRO-5H-ISOBENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    (5S,5AR,8AR,9R)-5-[[(4AR,7R,8R,8AS)-7,8-BIS(OXIDANYL)-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(3,5-DIMETHOXY-4-OXIDANYL-PHENYL)-5A,6,8A,9-TETRAHYDRO-5H-[2]BENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    A820047
    23724511
    (8AR,9R)-5-[[(2R,4AR,6R,7R,8R)-7,8-DIHYDROXY-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDRO-5H-[2]BENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    NSC-758667
    NSC758667
    CCG-39074
    PHARMAKON1600-01504094
    TENIPOSIDE [USAN]
    CHEMBL2355508
    DSSTOX_GSID_23638
    DSSTOX_RID_77122
    SCHEMBL3907
    DSSTOX_CID_3638
    NCGC00095098-01
    5284623
    FURO[3',4':6,7]NAPHTHO[2,3-D]-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-[[4,6-O-[(R)-2-THIENYLMETHYLENE]-.BETA.-D-GLUCOPYRANOSYL]OXY]-, (5R,5AR,8AR,9S)-
    (5S,5AR,8AR,9R)-5-[[(2R,4AR,6R,7R,8R,8AS)-7,8-DIHYDROXY-2-(2-THIENYL)-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(4-HYDROXY-3,5-DIMETHOXY-PHENYL)-5A,6,8A,9-TETRAHYDRO-5H-ISOBENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    (5R,5AR,8AR,9S)-9-(((2R,4AR,6R,7R,8R,8AS)-7,8-DIHYDROXY-2-(THIOPHEN-2-YL)HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL)OXY)-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPH
    AB01274729-01
    W-5144
    AB2000293
    AB0011611
    SC-15960
    HY-13761
    FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-((4,6-O-(2-THIENYLMETHYLENE)-BETA-D-GLUCOPYRANOSYL)OXY)-, (5R-(5ALPHA,5ABETA,8AALPHA,9BETA(R*)))-
    TENIPOSIDE-SUPPLIED BY SELLECK CHEMICALS
    KS-5147
    CS-1366
    957E6438QA
    VUMON;VM-26;VEHEM;NSC 122819
    AKOS015896073
    ZINC4099009
    AOB5608
    GTPL6843
    SCHEMBL3908
    VM26
    VUMONREG
    (5S,5AR,8AR,9R)-5-[[(2R,4AR,6R,7R,8R,8AS)-7,8-DIHYDROXY-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDRO-5H-[2]BENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    113634-EP2298754A1
    113634-EP2281820A2
    452548
    (5S,5AR,8AR,9R)-5-[(7,8-DIHYDROXY-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL)OXY]-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDRO-5H-[2]BENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    BC218913
    AKOS015964513
    SCHEMBL12278906
    (5S,5AR,8AR,9R)-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-8-OXO-5,5A,6,8,8A,9-HEXAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-5-YL 4,6-O-(2-THIENYLMETHYLENE)HEXOPYRANOSIDE
    275784
    FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-((4,6-O-(2-THIENYLMETHYLENE)-D-GLUCOPYRANOSYL)OXY)-, (5R-(5ALPHA,5ABATA,8AALPHA,9BETA))-
    (5AR,8AR,9R)-5-[[(4AR,7R,8R,8AS)-7,8-DIHYDROXY-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDRO-5H-[2]BENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    THO[2,3-D][1,3]DIOXOL-6(5AH)-ONE
    (10R,11R,15R)-16-{[(4AR,7R,8R,8AS)-7,8-DIHYDROXY-2-(THIOPHEN-2-YL)-HEXAHYDRO-2H-PYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY}-10-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-4,6,13-TRIOXATETRACYCLO[7.7.0.0(3),?.0(1)(1),(1)?]HEXADECA-1(9),2,7-TRIEN-12-ONE
    PL058972
    (5AR,8AR,9R)-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-8-OXO-5,5A,6,8,8A,9-HEXAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-5-YL 4,6-O-(THIOPHEN-2-YLMETHYLIDENE)-D-GLUCOPYRANOSIDE
    107642
    FURO[3',4':6,7]NAPHTHO[2,3-D]-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-[[4,6-O-(2-THIENYLMETHYLENE)-.BETA.-D-GLUCOPYRANOSYL)
    FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-((4,6-O-(2-THIENYLMETHYLENE)-.BETA.-D-GLUCOPYRANOSYL)OXY)-, (5R-(5.ALPHA.,5A.BETA.,8A.ALPHA.,9.BETA.(R*)))-
    9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-8-OXO-5,5A,6,8,8A,9-HEXAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-5-YL 4,6-O-(THIOPHEN-2-YLMETHYLIDENE)HEXOPYRANOSIDE
    5-[[7,8-DIHYDROXY-2-(2-THIENYL)-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(4-HYDROXY-3,5-DIMETHOXY-PHENYL)-5A,6,8A,9-TETRAHYDRO-5H-ISOBENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    5-[(7,8-DIHYDROXY-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL)OXY]-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDRO-5H-[2]BENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    16-{[7,8-DIHYDROXY-2-(THIOPHEN-2-YL)-HEXAHYDRO-2H-PYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY}-10-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-4,6,13-TRIOXATETRACYCLO[7.7.0.0?,?.0??,??]HEXADECA-1,3(7),8-TRIEN-12-ONE
    16-{[7,8-DIHYDROXY-2-(THIOPHEN-2-YL)-HEXAHYDRO-2H-PYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY}-10-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-4,6,13-TRIOXATETRACYCLO[7.7.0.0(3),?.0(1)(1),(1)?]HEXADECA-1,3(7),8-TRIEN-12-ONE
    [5R-[5.ALPHA.,5A.BETA.,8A.ALPHA.,9.BETA.(R*)]]-5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-9-[[4,6-O-(2-THIENYLMETHYLENE)-.BETA.-D-GLUCOPYRANOSYL]OXY]FURO[3',4':6,7]-NAPHTHO[2,3-D]-1,3-DIOXOL-6(5AH)-ONE
    EPIPODOPHYLLOTOXIN, 4'-DEMETHYL-, 9-(4,6-O-2-THENYLIDENE-.BETA.-D-GLUCOPYRANOSIDE)
    4'-DEMETHYLEPIPODOPHYLLOTOXIN 9-[4,6-O-(R)-2-THENYLIDENE-.BETA.-D-GLUCOPYRANOSIDE]
    4'-DEMETHYLEPIPODOPHYLLOTOXIN 9-(4,6-O-2-THENYLIDENE-.BETA.-D-GLUCOPYRANOSIDE)
    4'-DEMETHYL 1-O-(4,6-O,O-(2-THENYLIDENE)-.BETA.-D-GLUCOPYRANOSYL)EPIPODOPHYLLOTOXIN
    EPIPODOPHYLLOTOXIN-.BETA.-D-THENYLIDENE-GLUCOSIDE, 4'-DEMETHYL-
    6708778
    (8AR,9R)-9-[4-HYDROXY-3,5-BIS(METHYLOXY)PHENYL]-8-OXO-5,5A,6,8,8A,9-HEXAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-5-YL 4,6-O-(2-THIENYLMETHYLIDENE)-BETA-D-GLUCOPYRANOSIDE
    (8AR,9R)-5-[[(4AR,6R,7R,8R,8AS)-7,8-DIHYDROXY-2-THIOPHEN-2-YL-4,4A,6,7,8,8A-HEXAHYDROPYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY]-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5A,6,8A,9-TETRAHYDRO-5H-[2]BENZOFURO[6,5-F][1,3]BENZODIOXOL-8-ONE
    71752354
    113634-EP2274983A1
    CAS-29767-20-2
    TOX21_111421
    SR-01000775528-2
    3B2-1312
    SR-01000775528
    FT-0601556
    TC-030273
    PL027443
    DR003448
    AN-15543
    NRUKOCRGYNPUPR-UHFFFAOYSA-N
    CTK8E8745
    BDBM87330
    SCHEMBL13809319
    CHEMBL1571037
    CID_5396
    VEHEM-SANDOZ
    TENOPOSIDE
    5396

    Drug Info:

    Drug Categories topoisomerase inhibitors
    Drug Categories topoisomerase ii inhibitors
    Drug Categories therapeutic uses
    Drug Categories podophyllotoxin derivatives
    Drug Categories pharmacologic actions
    Drug Categories myelosuppressive agents
    Drug Categories molecular mechanisms of pharmacological action
    Drug Categories immunosuppressive agents
    Drug Categories glycosides
    Drug Categories glucosides
    Drug Categories enzyme inhibitors
    Drug Categories cytochrome p-450 cyp3a4 substrates
    Drug Categories cytochrome p-450 cyp3a inhibitors
    Drug Categories cytochrome p-450 cyp2c9 inhibitors
    Drug Categories cytochrome p-450 cyp2c19 substrates
    Drug Categories chemical actions and uses
    Drug Categories carbohydrates
    Drug Categories bcrp/abcg2 substrates
    Drug Categories antineoplastic and immunomodulating agents
    Drug Categories antineoplastic agents
    Drug Groups approved
    Drug Type small molecule
    Drug Type drug/small molecule
    ATC l01cb(podophyllotoxin derivatives)
    Drug Class antineoplastic agents
    Year of Approval 1992
    FDA Approval 1992
    Drug Class small molecule
    Drug Indications Antineoplastic Agents
    (6 More Sources)