• Pexmetinib CHEMBL3545297

    Alternate Names:

    Pexmetinib
    ARRY-614
    UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-((5-FLUORO-2-((1-(2-HYDROXYETHYL)-1H-INDAZOL-5-YL)OXY)PHENYL)METHYL)-
    N-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-N'-(5-FLUORO-2-(1-(2-HYDROXYETHYL)-1H-INDAZOL-5-YLOXY)BENZYL)UREA
    945614-12-0
    1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(5-FLUORO-2-(1-(2-HYDROXYETHYL)-1H-INDAZOL-5-YLOXY)BENZYL)UREA
    1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-((5-FLUORO-2-(1-(2-HYDROXYETHYL)-1H-INDAZOL-5-YLOXY)PHENYL)METHYL)UREA
    3750D0U8B5
    LNMRSSIMGCDUTP-UHFFFAOYSA-N
    PEXMETINIB [INN]
    24765037
    UNII-3750D0U8B5
    SCHEMBL379035

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications for treatment of myelodysplastic syndrome
    (0 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Trial Name ARRY-614
    Novel drug target Novel Target
    Mechanism of Interaction MAP kinase p38 alpha inhibitor

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase TIE-2 inhibitor
    Direct Interaction yes
    Trial Name ARRY-614

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name ARRY-614
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name ARRY-614
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name ARRY-614
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name ARRY-614
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name ARRY-614
    Novel drug target Novel Target

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications for treatment of myelodysplastic syndrome
    Drug Class Small molecule
    FDA Approval not approved

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    SCHEMBL379035 Drug Synonym
    UNII-3750D0U8B5 pubchem_primary_name
    24765037 PubChem CID

    Drug Info:

    Publications:

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications: