DGIdb - PIRENZEPINE Drug Record

PIRENZEPINE CHEMBL9967 FDA Approved

Alternate Names:

Gastri P
Pirenzepine
Gastrozepin
Ulopine
Stomazepin
Regastric
Ranclic
Pizepine
Pirodeine
Pirepine
Pin
Pilenzel
Muszepin
Lonzepin
Lizepine
Kiccalzin
Kawaipin
Karoderin
Gaszepin
Gastsion
Gastrozepin Tab 50mg
Gaspin
Garendopine
Folinzepin
Anquwei
28797-61-7
11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one
DB00670
2-[2-(4-METHYLPIPERAZIN-1-YL)ACETYL]-2,4,9-TRIAZATRICYCLO[9.4.0.0?,?]PENTADECA-1(11),3(8),4,6,12,14-HEXAEN-10-ONE
2-[2-(4-METHYLPIPERAZIN-1-YL)ACETYL]-2,4,9-TRIAZATRICYCLO[9.4.0.0(3),?]PENTADECA-1(15),3(8),4,6,11,13-HEXAEN-10-ONE
PDSP1_000965
2-[2-(4-METHYLPIPERAZIN-1-YL)ACETYL]-2,4,9-TRIAZATRICYCLO[9.4.0.0(3),?]PENTADECA-1(11),3(8),4,6,12,14-HEXAEN-10-ONE
11-[2-(4-METHYLPIPERAZIN-1-YL)ETHANOYL]-5H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE;HYDROCHLORIDE
11-[2-(4-METHYLPIPERAZIN-1-YL)ACETYL]-5H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE;HYDROCHLORIDE
11-[2-(4-METHYLPIPERAZIN-1-YL)-ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
11-[2-(4-METHYL-1-PIPERAZINYL)-1-OXOETHYL]-5H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE;HYDROCHLORIDE
11-[(4-METHYL-1-PIPERAZINYL)ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE #
11-[2-(4-METHYLPIPERAZINO)ACETYL]-5H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE;HYDROCHLORIDE
3B3-082080
AB00053603-08
FT-0600051
PL042895
PL002493
NCGC00015836-12
NCGC00015836-10
NCGC00015836-07
NCGC00015836-06
NCGC00015836-05
NCGC00015836-04
CCG-205042
3G0285N20N
TOX21_110239_1
AKOS015969751
ZINC19632927
DAP000492
TOX21_110239
MOLPORT-002-673-624
CTK6I3129
BDBM39341
CID_185248
GTPL328
SCHEMBL41705
5,11-DIHYDRO-11-[(4-METHYL-1-PIPERAZINYL)ACETYL]-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
CID4848
SMR000058502
CAS-28797-61-7
6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE, 5,11-DIHYDRO-11-[(4-METHYL-1-PIPERAZINYL)ACETYL]-
MLS000069702
BRD-K89375097-300-05-4
L000485
DSSTOX_GSID_23487
DSSTOX_RID_77049
5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)ACETYL)-6H-PYRIDO(2,3-B)(1,4)BENZODIAZEPIN-6-ONE
11-[2-(4-METHYLPIPERAZIN-1-YL)ACETYL]-5H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
D08389
C07508
DSSTOX_CID_3487
AB00053603
CAS-29868-97-1
LS-133128
NCGC00024297-05
NCGC00024297-04
NCGC00024297-02
NCGC00015836-09
NCGC00015836-08
NCGC00015836-03
NCGC00015836-02
NCGC00015836-01
IDI1_000127
6H-PYRIDO(2,3-B)(1,4)BENZODIAZEPIN-6-ONE, 5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)ACETYL)-
PDSP2_000949
HMS2089K21
RMHMFHUVIITRHF-UHFFFAOYSA-N
NINDS_000127
KBIO3_002445
KBIO2_006994
KBIO2_004426
KBIO2_001858
KBIO1_000127
BPBIO1_000196
11-[(4-METHYLPIPERAZIN-1-YL)ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
SPBIO_002117
SPBIO_001494
DIVK1C_000127
BIO-0807
KBIOSS_001858
KBIOGR_000794
BSPBIO_002945
BSPBIO_000178
LOPAC0_000962
BRN 0628987
L-S 519
AC1L1J3B
LS-519
LOPAC-P-7412
EINECS 249-228-4
SPECTRUM5_001344
SPECTRUM4_000437
SPECTRUM3_001453
SPECTRUM2_001417
PRESTWICK3_000129
PRESTWICK2_000129
PRESTWICK1_000129
PRESTWICK0_000129
C19H21N5O2
TOCRIS-1071
SPECTRUM_001378
PIRENZEPINE GASTROZEPIN
UNII-3G0285N20N
CHEBI:8247
PIRENZEPINE (INN)
PIRENZEPINE [INN:BAN]
ULCOSAN
GASTERIL
PIRENZEPINA [INN-SPANISH]
PIRENZEPINUM [INN-LATIN]
PYRENZEPINE
GASTROTSEPIN
PIRENZEPINA
PIRENZEPINUM
PIRENZEPIN
4848
9711
135650832
328

Drug Info:

Drug Categories	therapeutic uses
Drug Categories	physiological effects of drugs
Drug Categories	pharmacologic actions
Drug Categories	neurotransmitter agents
Drug Categories	muscarinic antagonists
Drug Categories	molecular mechanisms of pharmacological action
Drug Categories	heterocyclic compounds, 2-ring
Drug Categories	heterocyclic compounds
Drug Categories	gastrointestinal agents
Drug Categories	drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)
Drug Categories	drugs for acid related disorders
Drug Categories	cholinergic antagonists
Drug Categories	cholinergic agents
Drug Categories	chemical actions and uses
Drug Categories	benzodiazepinones
Drug Categories	benzodiazepines
Drug Categories	benzazepines
Drug Categories	anti-ulcer agents
Drug Categories	alimentary tract and metabolism
Drug Groups	approved
Drug Type	small molecule
FDA Approval	not approved by the FDA
Drug Class	small molecule
Drug Indications	Antispasmodics
Drug Indications	GI Anti-Ulcer Agents, anticholinergic
Drug Class	gi anti-ulcer agents, anticholinergic
Year of Approval	not approved by the fda
Drug Class	antispasmodics

(2 More Sources)

Publications:

Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Pedretti et al., 2003, Autonomic modulation during acute myocardial ischemia by low-dose pirenzepine in conscious dogs with a healed myocardial infarction: a comparison with beta-adrenergic blockade., J. Cardiovasc. Pharmacol.

PIRENZEPINE CHRM1

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? True

Publications:

Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

Pedretti et al., 2003, Autonomic modulation during acute myocardial ischemia by low-dose pirenzepine in conscious dogs with a healed myocardial infarction: a comparison with beta-adrenergic blockade., J. Cardiovasc. Pharmacol.

PIRENZEPINE CHRM2

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

Publications:
PIRENZEPINE CHRM3

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

Publications:
PIRENZEPINE CHRM4

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

Publications:
PIRENZEPINE CHRM5

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

Publications:

DrugBank: DB00670

Version: 5.0.8

Alternate Names:

PIRENZEPINE DrugBank Drug Name

11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one Drug Synonym

28797-61-7 CAS Number

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories alimentary tract and metabolism

Publications:

Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

Pedretti et al., 2003, Autonomic modulation during acute myocardial ischemia by low-dose pirenzepine in conscious dogs with a healed myocardial infarction: a comparison with beta-adrenergic blockade., J. Cardiovasc. Pharmacol.

TEND: PIRENZEPINE
- Version: 01-August-2011
Alternate Names:

PIRENZEPINE Primary Drug Name

Drug Info:

Year of Approval not approved by the fda

Drug Class antispasmodics

Drug Class gi anti-ulcer agents, anticholinergic

Publications:
TdgClinicalTrial: PIRENZEPINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications GI Anti-Ulcer Agents, anticholinergic

Drug Indications Antispasmodics

Drug Class small molecule

Publications:
PubChem: PIRENZEPINE
- Version: 09-Feb-2016
Alternate Names:

PIRENZEPINE pubchem_primary_name

4848 PubChem CID

PIRENZEPIN Drug Synonym

Drug Info:

Publications:
TTD: DAP000492
- Version: 4.3.02 (25-August-2011)
Alternate Names:

PIRENZEPINE GASTROZEPIN Drug Synonym

5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)ACETYL)-6H-PYRIDO(2,3-B)(1,4)BENZODIAZEPIN-6-ONE Drug Synonym

NCGC00024297-02 Drug Synonym

Drug Info:

Publications:
GuideToPharmacologyInteractions: 328
- Version: 27-September-2017
Alternate Names:

PIRENZEPINE GuideToPharmacology Ligand Name

135650832 PubChem Drug SID

Drug Info:

Publications:

Specific Action of the Ligand	Antagonist
Endogenous Drug?	False
Direct Interaction?	True

PIRENZEPINE	DrugBank Drug Name
11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one	Drug Synonym
28797-61-7	CAS Number

PIRENZEPINE	pubchem_primary_name
4848	PubChem CID
PIRENZEPIN	Drug Synonym

PIRENZEPINE	GuideToPharmacology Ligand Name
135650832	PubChem Drug SID

PIRENZEPINE Drug Record

PIRENZEPINE CHEMBL9967 FDA Approved

Alternate Names:

Drug Info:

Publications:

PIRENZEPINE CHRM1

Interaction Types: antagonist

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False Direct Interaction? True

PIRENZEPINE CHRM2

Interaction Types: antagonist

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False Direct Interaction? False

Publications:

PIRENZEPINE CHRM3

Interaction Types: antagonist

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False Direct Interaction? False

Publications:

PIRENZEPINE CHRM4

Interaction Types: antagonist

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False Direct Interaction? False

Publications:

PIRENZEPINE CHRM5

Interaction Types: antagonist

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False Direct Interaction? False

Publications:

DrugBank: DB00670

Alternate Names: PIRENZEPINE DrugBank Drug Name 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one Drug Synonym 28797-61-7 CAS Number

Drug Info: Drug Type small molecule Drug Groups approved Drug Categories alimentary tract and metabolism

TEND: PIRENZEPINE

Alternate Names: PIRENZEPINE Primary Drug Name

Drug Info: Year of Approval not approved by the fda Drug Class antispasmodics Drug Class gi anti-ulcer agents, anticholinergic

Publications:

TdgClinicalTrial: PIRENZEPINE

Alternate Names:

Drug Info: Drug Indications GI Anti-Ulcer Agents, anticholinergic Drug Indications Antispasmodics Drug Class small molecule

Publications:

PubChem: PIRENZEPINE

Alternate Names: PIRENZEPINE pubchem_primary_name 4848 PubChem CID PIRENZEPIN Drug Synonym

Drug Info:

Publications:

TTD: DAP000492

Alternate Names: PIRENZEPINE GASTROZEPIN Drug Synonym 5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)ACETYL)-6H-PYRIDO(2,3-B)(1,4)BENZODIAZEPIN-6-ONE Drug Synonym NCGC00024297-02 Drug Synonym

Drug Info:

Publications:

GuideToPharmacologyInteractions: 328

Alternate Names: PIRENZEPINE GuideToPharmacology Ligand Name 135650832 PubChem Drug SID

Drug Info:

Publications:

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? True

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

Interaction Types:

antagonist

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? False

Alternate Names:

PIRENZEPINE DrugBank Drug Name

11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one Drug Synonym

28797-61-7 CAS Number

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories alimentary tract and metabolism

Alternate Names:

PIRENZEPINE Primary Drug Name

Drug Info:

Year of Approval not approved by the fda

Drug Class antispasmodics

Drug Class gi anti-ulcer agents, anticholinergic

Drug Info:

Drug Indications GI Anti-Ulcer Agents, anticholinergic

Drug Indications Antispasmodics

Drug Class small molecule

Alternate Names:

PIRENZEPINE pubchem_primary_name

4848 PubChem CID

PIRENZEPIN Drug Synonym

Alternate Names:

PIRENZEPINE GASTROZEPIN Drug Synonym

5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)ACETYL)-6H-PYRIDO(2,3-B)(1,4)BENZODIAZEPIN-6-ONE Drug Synonym

NCGC00024297-02 Drug Synonym

Alternate Names:

PIRENZEPINE GuideToPharmacology Ligand Name

135650832 PubChem Drug SID