• NEFAZODONE CHEMBL623 FDA Approved

    Alternate Names:

    Nefazodone
    CID4449
    NEFAZODONE (INN)
    4449
    BRD-K90789829-003-03-3
    NCGC00165846-02
    SMR000550487
    NEFAZODONE [INN:BAN]
    83366-66-9
    NEFAZODONA [SPANISH]
    C25H32CLN5O2
    MLS001165769
    NCGC00165846-01
    DB01149
    LS-156497
    205126
    NEFAZODONUM [LATIN]
    CHEBI:7494
    MLS000759458
    2-{3-[4-(3-CHLOROPHENYL)PIPERAZIN-1-YL]PROPYL}-5-ETHYL-4-[2-(PHENYLOXY)ETHYL]-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE
    2-[3-[4-(3-CHLOROPHENYL)-1-PIPERAZINYL]PROPYL]-5-ETHYL-2,4-DIHYDRO-4-(2-PHENOXYETHYL)-3H-1,2,4-TRIAZOL-3-ONE
    L001196
    1-(3-(4-(M-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-3-ETHYL-4-(2-PHENOXYETHYL)-DELTA2-1,2,4-TRIAZOLIN-5-ONE
    1-(3-(4-(3-CHLORPHEYL-1-PIPERAZINYLPROPYL)-3-ETHYL-4,5-DIHYDRO-4-(2-PHENOXYETHYL)-1,2,4-TRIAZOL-5-ON
    NEFAZODONA
    NEFAZODONE HCL
    HMS2090D17
    2-[3-[4-(3-CHLOROPHENYL)PIPERAZIN-1-YL]PROPYL]-5-ETHYL-4-(2-PHENOXYETHYL)-1,2,4-TRIAZOL-3-ONE
    MOLPORT-003-849-346
    C07256
    NEFAZODONUM
    BIDD:GT0789
    2-{3-[4-(3-CHLOROPHENYL)PIPERAZIN-1-YL]PROPYL}-5-ETHYL-4-(2-PHENOXYETHYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE
    D08257
    MLS001195657
    AC1L1I6V
    3H-1,2,4-TRIAZOL-3-ONE, 2-(3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-5-ETHYL-2,4-DIHYDRO-4-(2-PHENOXYETHYL)-
    3H-1,2,4-TRIAZOL-3-ONE, 2,4-DIHYDRO-2-3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-5-ETHYL-4-(2-PHENOXYETHYL)-
    DAP000042
    82752-99-6 (HYDROCHLORIDE)
    UNII-59H4FCV1TF
    MOLPORT-002-885-843
    Serzone-5ht2
    Serzone
    Nefazodone Hydrochloride
    Lin-nefazodone
    Dutonin
    2-[3-[4-(3-CHLOROPHENYL)-1-PIPERAZINYL]PROPYL]-5-ETHYL-4-(2-PHENOXYETHYL)-2H-1,2,4-TRIAZOL-3(4H)-ONE
    2-[3-[4-(3-CHLOROPHENYL)-1-PIPERAZINYL]PROPYL]-5-ETHYL-4-(2-PHENOXYETHYL)-1,2,4-TRIAZOL-3-ONE
    2-(3-[4-(3-CHLOROPHENYL)-1-PIPERAZINYL]PROPYL)-5-ETHYL-4-(2-PHENOXYETHYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE #
    1-{3-[4-(3-CHLOROPHENYL)PIPERAZIN-1-YL]PROPYL}-3-ETHYL-4-(2-PHENOXYETHYL)-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-5-ONE
    A840565
    117201-EP2298776A1
    117201-EP2298765A1
    117201-EP2298764A1
    117201-EP2275420A1
    AB00640019-14
    FT-0654783
    KB-213402
    HE394836
    DR002913
    BC205772
    AN-36029
    AK110700
    AJ-23377
    NCGC00165846-03
    VA11366
    NSC-760344
    CCG-213026
    AKOS015907198
    NSC760344
    BDBM50069447
    ZINC538065
    PHARMAKON1600-01502314
    HMS3372C02
    HMS3264K04
    HMS2231I17
    GTPL7247
    SCHEMBL35089
    59H4FCV1TF
    NEFADARREG
    1-(3-(4-(3-CHLOROPHENYL)PIPERAZIN-1-YL)PROPYL)-3-ETHYL-4-(2-PHENOXYETHYL)-1H-1,2,4-TRIAZOL-5(4H)-ONE
    VRBKIVRKKCLPHA-UHFFFAOYSA-N
    135652418
    PTH-(1-34) (RAT)
    178103821
    7247

    Drug Info:

    FDA Approval 1994
    Drug Class small molecule
    Drug Indications Antidepressive Agents, Second-Generation
    Drug Categories therapeutic uses
    Drug Categories serotonin modulators
    Drug Categories selective serotonin reuptake inhibitors
    Drug Categories psychotropic drugs
    Drug Categories psychoanaleptics
    Drug Categories pharmacologic actions
    Drug Categories p-glycoprotein/abcb1 inducers
    Drug Categories nervous system
    Drug Categories heterocyclic compounds, 1-ring
    Drug Categories heterocyclic compounds
    Drug Categories cytochrome p-450 cyp3a4 substrates
    Drug Categories cytochrome p-450 cyp3a4 inhibitors (strong)
    Drug Categories cytochrome p-450 cyp3a inhibitors
    Drug Categories cytochrome p-450 cyp2d6 substrates
    Drug Categories cytochrome p-450 cyp2d6 inhibitors
    Drug Categories cytochrome p-450 cyp1a2 inhibitors (weak)
    Drug Categories cytochrome p-450 cyp1a2 inhibitors
    Drug Categories chemical actions and uses
    Drug Categories central nervous system agents
    Drug Categories azoles
    Drug Categories antidepressive agents, second-generation
    Drug Categories antidepressive agents
    Drug Categories analgesics
    Drug Categories alpha1 antagonists
    Drug Groups withdrawn
    Drug Groups approved
    Drug Type small molecule
    Drug Class antidepressive agents, second-generation
    Year of Approval 1994
    (3 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Details of the Assay for Interaction Dissociation constant of [3H]- nisoxatine <i>vs</i>. nefazodone.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Specific Action of the Ligand Inhibition

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    NEFAZODONE Primary Drug Name

    Drug Info:
    Year of Approval 1994
    Drug Class antidepressive agents, second-generation

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Antidepressive Agents, Second-Generation
    Drug Class small molecule
    FDA Approval 1994

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    MOLPORT-002-885-843 Drug Synonym
    UNII-59H4FCV1TF Drug Synonym
    82752-99-6 (HYDROCHLORIDE) Drug Synonym

    Drug Info:

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    NEFAZODONE pubchem_primary_name
    4449 PubChem CID
    NEFAZODONA Drug Synonym

    Drug Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    PTH-(1-34) (RAT) GuideToPharmacology Ligand Name
    135652418 PubChem Drug SID

    Drug Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    NEFAZODONE GuideToPharmacology Ligand Name
    178103821 PubChem Drug SID

    Drug Info:

    Publications:

    • Version: 15-September-2017

    Alternate Names:

    Drug Info:

    Publications: