• NAPROXEN CHEMBL154 FDA Approved

    Alternate Names:

    Timpron 500 EC
    Laraflex
    Aleve
    Timpron 250 EC
    Rheuflex 250
    Nycopren
    Stirlescent
    Naprosyn 375
    Naproxen
    Naprosyn EC
    Rheuflex 500
    Feminax Ultra
    Grenoxal
    Prosaid
    Arthrosin 250 EC
    Valrox
    Arthrosin 250
    Vimovo
    Rimoxyn
    Kenosyn
    Condrotec
    Timpron
    Napratec OP
    Arthrosin 500
    Arthrosin 500 EC
    Pranoxen Continus
    Naprosyn
    RS-3540
    Equiproxen
    Anaprox
    Naprelan
    Ec-Naprosyn
    C680
    Naproxen Tablets
    Naproxen Sodium Tablets
    Naproxen Sodium DS
    Naproxen Sodium Caplets
    Naproxen Sodium All Day Pain Relief
    Naproxen Sodium (nsaid) Fever Reducer/ Pain Reliever
    Naproxen Pain Relief
    Naproxen Menstrual Pain Relief
    Naproxen Liquid Gels
    Naproxen Liquid Gel Capsules
    Naproxen Kit
    Naproxen EC
    Naproxen Delayed Release
    Naproxen Capsules 200 mg
    Naproxen Caplets All Day Relief for Pain
    Naproxen All Day Relief for Pain
    Naproxen 500 Tab 500mg
    Naproxen 250 Tab 250mg
    Naproxen 125 Tab 125mg
    Naproval
    Naprosyne
    Naprosyn-SR Tab 750mg
    Naprosyn Sus 25mg/ml
    Naprosyn Sup 500mg
    Naprosyn SR
    Naprosyn Entero
    Naprosyn E Tab 500mg
    Naprosyn E Tab 375mg
    Naprosyn E Tab 250mg
    Naprosyn E 250mg Tablets - Ect
    Naprosyn CR
    Naprosyn 500 Mg Tablets
    Naprosyn 500 Mg Suppositories
    Naprosyn 375mg Tablets
    Naprosyn 375mg
    Naprosyn 250mg Tablets
    Naprosyn 250mg
    Naprometin
    Mylan-naproxen/esomeprazole Mr
    Mylan-naproxen EC
    Motrimax 12 Hour Tablets
    Motrimax 12 Hour
    Modern Pain Medicine
    Mobilat
    Midol Extended Relief
    Messelxen
    Menstridol
    Members Mark Naproxen Sodium
    Melgar
    Medique Mediproxen
    Maxidol Liquid Gels
    Lil Drug Store Pain Relief All Day
    Lexinax
    Leader Sinus and Cold-D
    Leader Naproxen Sodium
    Leader All Day Pain Relief
    Leader All Day
    Kirkland Signature Naproxen Sodium
    Jinkangpuli
    Iraxen
    Inza
    Inflamax
    Improstan
    Humana Pharmacy All Day Pain Relief
    Honlow
    Healthy Accents Naproxen Sodium
    Healthy Accents All Day Pain Relief
    Health Mart Sinus and Cold D
    Health Mart Naproxen Sodium
    Good Sense Naproxen Sodium
    Good Sense All Day Pain Relief
    Good Neighbor Pharmacy Sinus and Cold D
    Good Neighbor Pharmacy Pain Relief All Day
    Good Neighbor Pharmacy Naproxen Sodium
    Gerinap
    Fulton Street Market Naproxen Sodium
    Formucare Naproxen Sodium Pain Reliever Fever Reducer
    Flogotone
    Flanax Pain and Fever Reliever
    Flanax Pain Reliever
    Flanax Naproxen
    Family Wellness Naproxen Sodium
    Fabralgina
    Exchange Select Naproxen Sodium
    Eurogesic
    Equipto - Naproxen External Cream Compounding Kit
    Equate Naproxen Sodium
    Equaline Naproxen Sodium
    Equaline All Day Pain Relief
    Emoxen
    Emox
    EC-naproxen
    Dysmenalgit
    Dg Health Naproxen Sodium
    Dg Health All Day Pain Relief
    Deproxen
    Debril
    Congex
    Comfort Pac With Naproxen
    Careone Naproxen Sodium
    Careall Naproxen
    Care One Naproxen Sodium
    Care One All Day Pain Relief
    Xenar-CR
    Xenar
    Up and Up Sinus and Cold D
    Up and Up Naproxen Sodium
    Tundra
    Treximet
    Topcare Sinus and Cold D
    Topcare Naproxen Sodium
    Topcare All Day Pain Relief
    Ticoflex
    Theraproxen-90
    Theraproxen-500
    Theraproxen
    Teva-naproxen Sodium DS
    Teva-naproxen Sodium
    Teva-naproxen SR
    Teva-naproxen EC
    Teva-naproxen
    Tarproxen
    Synflex Tab 275mg
    Synflex DS Tab 550mg
    Sunmark Sinus and Cold D
    Sunmark Naproxen Sodium
    Sunmark All Day Relief
    Sudafed 12 Hour Pressure and Pain
    Smart Sense Naproxen Sodium
    Sinus and Cold D
    Simply Right Naproxen Sodium
    Signature Care Pain Relief
    Shoprite Naproxen Sodium
    Servinaprox
    Seladin
    Sanaprox
    Sallus Pain Relief Collection With Naproxen
    Sab-naproxen
    Rx Act Naproxen Sodium
    Rx Act All Day Pain Relief
    Rugby All Day Relief
    Riva-naproxen Sodium DS
    Riva-naproxen Sodium
    Riva-naproxen
    Riproxen
    Rhodiaprox - 500mg/sup
    Rexall All Day Pain Relief
    Reuxen
    Repro
    Releve
    Ratio-naproxen E
    Ratio-naproxen
    Proxen SR
    Proxen S
    Proxen
    Pronaxen
    Pro-naproxen EC - 500
    Pro-naproxen EC - 375
    Princeps
    Priaxen
    Prexan
    Preferred Plus Sinus and Cold D
    Pediapharm Naproxen Suspension
    Pain Zero
    Pain Relief All Day
    PMS-naproxen EC
    PMS-naproxen
    Nx 12 Hour
    Nu-naprox Tab 500mg
    Nu-naprox Tab 375mg
    Nu-naprox Tab 250mg
    Nu-naprox Tab 125mg
    Nu-naprox EC
    Nu-napro-NA DS
    Nu-napro-NA
    Ntp-naproxen Sodium DS
    Ntp-naproxen Sodium
    Ntp-naproxen EC
    Ntp-naproxen
    Novo-naprox Tab 125mg
    Nopain
    Noflam
    Neuralprona
    Naprux
    Naproxen-NA Tab 275mg
    Naproxen-NA Df -tab 550mg
    Naproxen-375 Tab 375mg
    Calmadol Pain Reliever
    Bumaflex N
    Bruproxen
    Bonyl
    Berkley and Jensen Naproxen Sodium
    Being Well All Day Pain Relief
    Bayer Aleve
    Ava-naproxen EC
    Apronax
    Apranax
    Apo-naproxen SR Tablets 750mg
    Apo-naproxen EC Tablets
    Apo-napro-NA Tab 275mg
    Apo-napro-NA DS Tab 550mg
    Apo Naproxen Tab 500mg
    Apo Naproxen Tab 375mg
    Apo Naproxen Tab 250mg
    Apo Naproxen Tab 125mg
    Apain
    Anaprox DS Tab 550mg
    Anaprox DS
    Alpron
    Alpoxen
    All Day Sinus and Cold D
    All Day Relief
    All Day Pain Relief Naproxen Sodium
    All Day Pain Relief
    Alidase
    Aleve PM
    Aleve Nighttime
    Aleve Liquid Gels
    Aleve Gelcaps
    Aleve Easy Open Arthritis Cap
    Aleve Caplets - Easy Open Arthritis Cap
    Aleve Caplets
    Aleve Back and Body Pain
    7 Select Naproxen Sodium
    22204-53-1
    Naprolag
    (S)-Naproxen
    (S)-2-(6-Methoxy-2-naphthyl)propanoic acid
    (S)-(+)-Naproxen
    (+)-2-(Methoxy-2-naphthyl)-propionic acid
    (+)-(S)-Naproxen
    (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
    DB00788
    TOX21_301953
    CS13959
    CS-2163
    AKOS005267223
    NSC757239
    NSC750183
    MFCD00010500
    DNC000992
    CCG-40130
    BDBM50339185
    ANW-24773
    NPS
    INCHI=1/C14H14O3/C1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/H3-9H,1-2H3,(H,15,16)/T9-/M0/S1
    ACT02593
    26159-31-9
    ZINC105216
    PHARMAKON1600-01500425
    HMS3649M13
    HMDB01923
    CTK8B1225
    GTPL5230
    57Y76R9ATQ
    2-NAPHTHALENEACETIC ACID, 6-METHOXY-ALPHA-METHYL-, (+)- (8CI)
    NAPROXEN (JP16/USP/INN)
    KSC911E2L
    DSSTOX_GSID_40686
    DSSTOX_RID_79542
    DSSTOX_CID_20686
    2-NAPHTHALENEACETIC ACID, 6-METHOXY-.ALPHA.-METHYL-, (S)-
    SCHEMBL3046
    2-(6-METHOXY-NAPHTHALEN-2-YL)-PROPIONIC ACID(NAPROXEN)
    EPITOPE ID:139974
    NAPROXEN2-(6-METHOXY-NAPHTHALEN-2-YL)-PROPIONIC ACID
    BRD-K59197931-236-09-6
    BRD-K59197931-001-02-9
    SR-01000075977-3
    4PO0
    4OR0
    PUBCHEM8102
    M1021
    FT-0082415
    TL8003659
    LS-124738
    NAPROSYN (TN)
    NCGC00161591-01
    NCGC00021127-01
    NCGC00016759-01
    IDI1_000242
    DB08298
    AC-1363
    ALEVEREG
    NINDS_000242
    NAPROSYREG
    MOLPORT-000-145-960
    NAPROXEN [USAN:BAN:INN:JAN]
    KBIO3_001567
    KBIO2_006593
    KBIO2_004025
    KBIO2_001457
    KBIO1_000242
    HMS500M04
    CMWTZPSULFXXJA-VIFPVBQESA-
    65126_FLUKA
    46482_FLUKA
    UPCMLD-DP001:001
    STOCK1N-50633
    N8280_SIAL
    46482_RIEDEL
    284785_ALDRICH
    SPBIO_002861
    SPBIO_000966
    SPECTRUM1500425
    DIVK1C_000242
    BIDD:GT0062
    ARONIS24306
    KBIOSS_001457
    KBIOGR_000597
    BSPBIO_002067
    LOPAC0_000792
    AC1Q4F4I
    AC1Q4F4H
    AC1Q4ET9
    AC1L4G3X
    UPCMLD-DP001
    SPECTRUM5_001327
    SPECTRUM4_000069
    SPECTRUM3_000514
    SPECTRUM2_001043
    PRESTWICK2_000791
    PRESTWICK1_000791
    PRESTWICK0_000791
    EQUIPROXEN (VETERINARY)
    SPECTRUM_000977
    PRESTWICK_349
    2-NAPHTHALENEACETIC ACID, 6-METHOXY-ALPHA-METHYL-, (+)-
    D-2-(6'-METHOXY-2'-NAPHTHYL)-PROPIONSAEURE [GERMAN]
    (+)-2-(METHOXY-2-NAPHTHYL)-PROPIONSAEURE [GERMAN]
    PROXINE
    PANOXEN
    NAPROSINE
    (2S)-2-(6-METHOXY-2-NAPHTHYL)PROPANOIC ACID
    D-2-(6'-METHOXY-2'-NAPHTHYL)-PROPIONSAEURE
    CAS-22204-53-1
    2-NAPHTHALENEACETIC ACID, 6-METHOXY-ALPHA-METHYL-, (S)-
    RS 3540
    DUK
    PROPIONIC ACID, 2-(6-METHOXY-2-NAPHTHYL)-, (+)-
    LASER
    NAPRIUM
    2-NAPHTHALENEACETIC ACID, 6-METHOXY-.ALPHA.-METHYL-, (+)-
    (S)-(+)-2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID; NAPROXEN
    (S)-(+)-2-(6-METHOXY-NAPHTHALEN-2-YL)-PROPIONIC ACID
    (+)-6-METHOXY-.ALPHA.-METHYL-2-NAPTHALENEACETIC ACID
    Q-201447
    (S)-2-(6-METHOXY-NAPHTHALEN-2-YL)-PROPIONIC ACID
    2-(6-METHOXY-2-NAPHTHYL)PROPANOIC ACID , (+)-
    AB00052049-04
    (2S)-2-(6-METHOXY(2-NAPHTHYL))PROPANOIC ACID
    M-5280
    J10145
    D00118
    C01517
    2-(S)-(6-METHOXY-2-NAPHTHYL)-PROPANOIC ACID
    W4580
    AM20060551
    ST2408284
    AB1009325
    SY015060
    OR138579
    HY-15030
    BR-72928
    BC208049
    AN-14988
    AK-72928
    AJ-11169
    NCGC00255562-01
    NCGC00016759-03
    NCGC00016759-02
    RTR-010461
    RP27889
    NSC-757239
    NSC-750183
    ME-0100
    MCULE-2589082817
    EINECS 244-838-7
    CMWTZPSULFXXJA-VIFPVBQESA-N
    HSDB 3369
    CCRIS 5265
    D-2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID
    MNPA
    METHOXYPROPIOCIN
    NAPROSIN
    UNII-57Y76R9ATQ
    CG 3117
    NAPROXENO [INN-SPANISH]
    NAPROXENUM [INN-LATIN]
    NAPROXENE [INN-FRENCH]
    NAXYN 500
    NAXYN 250
    (+)-2-(METHOXY-2-NAPHTHYL)-PROPIONSAEURE
    CHEBI:7476
    NAPROXI 500
    NAPROXI 250
    NAPROSYN LLE FORTE
    U-RITIS
    PROXEN LLE
    NAXEN F
    PROXEN LE
    NAPROSYN LLE
    NAPREN E
    DL NAPROXEN
    FLANAX FORTE
    ANAX
    ROXEN
    NARMA
    VINSEN
    VELSAY
    SUTONY
    SINTON
    RAHSEN
    PATXEN
    NAPXEN
    FLEXEN
    TRAUMOX
    TOHEXEN
    SUTOLIN
    SOPROXEN
    SINARTRIN
    PRAFENA
    NAXOPREN
    NAROCIN
    NAPRONTAG
    NAPRATEC
    HEADLON
    SARITILRON
    RHEUMAFLEX
    VERADOL
    DIOCODAL
    (2S)-2-(6-METHOXYNAPHTHALEN-2-YL)PROPANOIC ACID
    APO-NAPROXEN
    NAXYN
    NAXEN
    NAPREN
    NAPRIUS
    HMS2091H12
    HMS2089N21
    HMS1920P13
    DYSMENALGIT N
    FUXEN
    NAPOSIN
    NAPMEL
    NAPFLAM
    NALYXAN
    NAFASOL
    LEFAINE
    GENOXEN
    DAPROX
    ATIFLAN
    ARTAGEN
    NOVONAPROX
    LENIARTIL
    FLOGINAX
    FLEXIPEN
    DANAPROX
    CLINOSYN
    BIPRONYL
    ARTROXEN
    ARTRIXEN
    ARTHRISIL
    ANEXOPEN
    ACUSPRAIN
    (S)-2-(6-METHOXYNAPHTHALEN-2-YL)PROPANOIC ACID
    AXER
    NAIXAN
    NAPROXENO
    CALOSEN
    NAPROXENUM
    D-NAPROXEN
    NAPROXENE
    156391
    178101914
    5230
    1302
    4682
    APO-NAPRO-NA
    2-NAPHTHALENEACETIC ACID, 6-METHOXY-.ALPHA.-METHYL-, (.ALPHA.S)-
    CID156391
    DAP000968
    56547-15-0
    I14-106184
    3B3-003394
    2-NAPHTHALENEACETIC ACID, 6-METHOXY-?-METHYL-, (?S)-
    BRD-A87719232-001-02-4
    Q-201030
    I06-0050
    3B2-0168
    3B2-0167
    (RS)-2-(6-METHOXYNAPHTHALEN-2-YL)PROPANOIC ACID
    (+)-ALPHA-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID
    M-7686
    6-METHOXY-ALPHA-METHYL-2-NAPHTHALENEESSIGSAURE
    6-METHOXY-ALPHA-METHYL-2-NAPHTHALENACETIC ACID
    ST24027595
    M1220
    LT00452004
    FT-0638374
    FT-0602835
    AB00513799
    6-METHOXY-ALPHA-METHYL-2-NAPHTHYLACETIC ACID
    6-METHOXY-2-NAPHTHYL-ALPHA-METHYLACETIC ACID
    4CH-007732
    2-(6-METHOXYNAPHTHALENE-2-YL)PROPANOIC ACID
    TL8001846
    TC-114024
    LS-187192
    KB-163190
    DB-007955
    AB0013024
    6-METHOXY-A-METHYL-2-NAPHTHALENEACETIC ACID
    6-METHOXY-2NAPHTHYL-ALPHA-METHYLACETIC ACID
    SC-78606
    OR209168
    OR163932
    OR163829
    H385
    DR000497
    AK-40137
    AC-11494
    2-(6-METHOXYNAPHTH-2-YL)-PROPIONIC ACID
    NCGC00094733-03
    NCGC00094733-02
    NCGC00094733-01
    NCGC00021127-05
    NCGC00021127-04
    NCGC00021127-03
    NCGC00021127-02
    2-(6-METHOXY-2-NAPHTYL)PROPIONIC ACID
    TRA0033868
    MCULE-6293512671
    CCG-220045
    AKOS016038194
    AKOS000121315
    STK301546
    SBB029869
    BDBM50009860
    AR-1C8255
    ANW-25279
    EINECS 245-969-2
    HMS3374N03
    HMS2230K21
    HMS2095I11
    CTK7A8174
    SCHEMBL10029028
    BPBIO1_000187
    (2S)-2-(6-METHOXYNAPHTH-2-YL)PROPANOIC ACID
    SCHEMBL145769
    CHEMBL12952
    MLS006011863
    MLS002154184
    BSPBIO_000169
    OPREA1_018821
    AC1Q5RT0
    AC1L1B6B
    ACMC-209G7L
    PRESTWICK3_000045
    ACMC-209FTJ
    (RS)-NAPROXEN
    RACEMIC NAPROXEN
    NIAXAN
    PRANOXEN
    SMR001233475
    2-(6-METHOXY-NAPHTHALEN-2-YL)-PROPIONIC ACID
    RAC-NAPROXEN-13C,D3
    ST024763
    CMWTZPSULFXXJA-UHFFFAOYSA-N
    2-(6-METHOXY-2-NAPHTHYL)PROPANOIC ACID
    DL-NAPROXEN
    2-(6-METHOXYNAPHTHALEN-2-YL)PROPANOIC ACID
    23981-80-8
    C[C@@H](C1CCC2CC(CCC2C1)OC)C(=O)O
    7476
    618721
    50009860
    0004-6313-01
    PA450595
    135652632
    VARIANT MCH
    187051779
    LORLANTINIB

    Drug Info:

    Drug Class anti-inflammatory agents
    Year of Approval 1976
    Drug Categories therapeutic uses
    Drug Categories sensory system agents
    Drug Categories polycyclic hydrocarbons, aromatic
    Drug Categories polycyclic compounds
    Drug Categories physiological effects of drugs
    Drug Categories pharmacologic actions
    Drug Categories peripheral nervous system agents
    Drug Categories organic chemicals
    Drug Categories naphthalenes
    Drug Categories naphthaleneacetic acids
    Drug Categories molecular mechanisms of pharmacological action
    Drug Categories hydrocarbons, cyclic
    Drug Categories hydrocarbons, aromatic
    Drug Categories hydrocarbons
    Drug Categories gout suppressants
    Drug Categories genito urinary system and sex hormones
    Drug Categories enzyme inhibitors
    Drug Categories cytochrome p-450 cyp2c9 substrates
    Drug Categories cytochrome p-450 cyp2c8 substrates
    Drug Categories cytochrome p-450 cyp1a2 substrates
    Drug Categories cyclooxygenase inhibitors
    Drug Categories chemical actions and uses
    Drug Categories central nervous system agents
    Drug Categories antirheumatic agents
    Drug Categories antiinflammatory products for vaginal administration
    Drug Categories anti-inflammatory agents, non-steroidal
    Drug Categories anti-inflammatory agents
    Drug Categories analgesics, non-narcotic
    Drug Categories analgesics
    Drug Groups vet_approved
    Drug Groups approved
    Drug Type small molecule
    Drug Indications NSAID
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications antimigraine agent
    ATC m01ae(propionic acid derivatives)
    Drug Type drug/small molecule
    ATC m02aa(antiinflammatory preparations
    ATC g02cc(antiinflammatory products for vaginal administration)
    (8 More Sources)

    Publications:

    James et al., 2007, Selective COX-2 inhibitors, eicosanoid synthesis and clinical outcomes: a case study of system failure., Lipids
    Hassan-Alin et al., 2005, Lack of Pharmacokinetic Interaction between Esomeprazole and the Nonsteroidal Anti-Inflammatory Drugs Naproxen and Rofecoxib in Healthy Subjects., Clin Drug Investig
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    White, 2007, Cardiovascular effects of the selective cyclooxygenase-2 inhibitors., Subcell. Biochem.
    Dhir et al., 2007, Neuroprotective effect of nimesulide, a preferential COX-2 inhibitor, against pentylenetetrazol (PTZ)-induced chemical kindling and associated biochemical parameters in mice., Seizure
    Kumar et al., 2007, Cyclooxygenase inhibition attenuates 3-nitropropionic acid-induced neurotoxicity in rats: possible antioxidant mechanisms., Fundam Clin Pharmacol
    Albertini et al., 2007, COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy., Inflamm. Res.
    Ikenoue et al., 2000, Disease-induced alterations in plasma drug-binding proteins and their influence on drug binding percentages in dogs., Vet Q
    Tracy et al., 1997, Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation., Eur. J. Clin. Pharmacol.
    van Dijk et al., 2004, Potential interaction between acenocoumarol and diclofenac, naproxen and ibuprofen and role of CYP2C9 genotype., Thromb. Haemost.
    Shiotani et al., 2002, NSAID gastric ulceration: predictive value of gastric pH, mucosal density of polymorphonuclear leukocytes, or levels of IL-8 or nitrite., Dig. Dis. Sci.
    Barthwal et al., 1991, Management of IUD-associated menorrhagia in female rhesus monkeys (Macaca mulatta)., Adv Contracept
    Sipe et al., 1992, Modification of proinflammatory cytokine production by the antirheumatic agents tenidap and naproxen. A possible correlate with clinical acute phase response., J. Immunol.