• LUMACAFTOR CHEMBL2103870 FDA Approved

    Alternate Names:

    Lumacaftor
    VRT-826809
    VX-809
    BENZOIC ACID, 3-(6-(((1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPYL)CARBONYL)AMINO)-3-METHYL-2-PYRIDINYL)-
    3-{6-[1-(2,2-DIFLUORO-2H-1,3-BENZODIOXOL-5-YL)CYCLOPROPANEAMIDO]-3-METHYLPYRIDIN-2-YL}BENZOIC ACID
    3-[6-[[1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANECARBONYL]AMINO]-3-METHYLPYRIDIN-2-YL]BENZOIC ACID
    3-[6-[[1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANECARBONYL]AMINO]-3-METHYL-2-PYRIDYL]BENZOIC ACID
    3-(6-{[1-(2,2-DIFLUOROBENZO[1,3]DIOXOL-5-YL)CYCLOPROPANECARBONYL]AMINO}-3-METHYL-PYRIDIN-2-YL)BENZOI
    3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANE-1-CARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID
    3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID
    3-(6-(1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANE-1-CARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID
    3-(6-([1-(2,2-DIFLUORO-2H-1,3-BENZODIOXOL-5-YL)CYCLOPROPANE]AMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID
    1220975-12-1
    POUND MOLWEIGHT:452.4069264) , VX809, VX 809, 936727-05-8
    VX809, VX 809, 936727-05-8
    S-5955
    D10134
    A25628
    ST24028315
    TC-137995
    AJ-114588
    AB0008169
    SMR004702901
    KB-81477
    HY-13262
    HE137923
    HE069057
    EN002684
    BR-36922
    BC660192
    AN-16986
    AK-36922
    4CA-0760
    NCGC00346550-01
    VX-809-SUPPLIED BY SELLECK CHEMICALS
    QC-7245
    PB19466
    CS-0479
    AKOS015920205
    ZINC64033452
    VX-809/VX809
    ANW-49250
    ABP000707
    UFSKUSARDNFIRC-UHFFFAOYSA-N
    MOLPORT-009-198-874
    C24H18F2N2O5
    AOB2051
    CTK8B5597
    GTPL7481
    SCHEMBL377028
    MLS006011120
    EGP8L81APK
    LUMACAFTOR [USAN:INN]
    PUBCHEM22450
    S1565_SELLECK
    LUMACAFTOR (USAN)
    VX809, VX 809, VX-809
    3-{6-[1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANEAMIDO]-3-METHYLPYRIDIN-2-YL}BENZOIC ACID
    VRT 826809
    UNII-EGP8L81APK
    VX 809
    3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID
    VX809
    16678941
    936727-05-8
    W9631
    Orkambi
    3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid
    DB09280

    Drug Info:

    FDA Approval not approved
    Drug Class small molecule
    Drug Indications for treatment of cystic fibrosis
    Drug Categories respiratory system
    Drug Categories pyridines
    Drug Categories organic chemicals
    Drug Categories heterocyclic compounds, 2-ring
    Drug Categories heterocyclic compounds, 1-ring
    Drug Categories heterocyclic compounds
    Drug Categories dioxoles
    Drug Categories cytochrome p-450 cyp3a4 inducers (strong)
    Drug Categories cytochrome p-450 cyp3a inducers
    Drug Categories cytochrome p-450 cyp2c9 inhibitors
    Drug Categories cytochrome p-450 cyp2c9 inducers
    Drug Categories cytochrome p-450 cyp2c8 inhibitors
    Drug Categories cytochrome p-450 cyp2c8 inducers
    Drug Categories cytochrome p-450 cyp2c19 inducers
    Drug Categories cytochrome p-450 cyp2b6 inducers
    Drug Categories cystic fibrosis transmembrane conductance regulator
    Drug Categories amines
    Drug Groups approved
    Drug Type small molecule
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