• LORAZEPAM CHEMBL580 FDA Approved

    Alternate Names:

    Lorazepam
    Abbloraz
    Temesta
    WY-4036
    Ativan
    Lorazepam Preservative Free
    Lorazepam Intensol
    Loraz
    C619
    SOMAGEROL
    IDALPREM
    O-CHLOROXAZEPAM
    PSICOPAX
    WYPAX
    QUAIT
    SECURIT
    ALZAPAM
    L-LORAZEPAM ACETATE
    BONATRANQUAN
    PRO DORM
    LORAX
    DAP000237
    D00365
    3821
    SEDAZIN
    ANXIEDIN
    PA450267
    APLACASSEE
    DELORMETAZEPAM
    0054-3532-44
    O-CHLOROOXAZEPAM
    ALMAZINE
    3958
    156663
    2243278
    SEDATIVAL
    PUNKTYL
    TAVOR
    46508468
    LORSILAN
    EMOTIVAL
    DB00186
    LORABENZ
    C1CCC(C(C1)C2=NC(C(=O)NC3C2CC(CC3)CL)O)CL
    L1764_SIGMA
    LORAZEPAM WYETH BRAND
    LORAZEPAM MEDICAL
    NSC 289758
    APO-LORAZEPAM
    LORAZIN
    LORAZEPAM MEDICAL BRAND
    HMS503A11
    LORAZEPAM LLORENS BRAND
    2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-
    NU-PHARM BRAND OF LORAZEPAM
    DIVK1C_000965
    WYETH, ORFIDAL
    APOLORAZEPAM
    NORLORMETAZEPAM
    LORAZEPAM GENERICON
    LORAZEPAM-RATIOPHARM
    LORAZEPAM BAXTER BRAND
    7-CHLORO-5-(2-CHLOROPHENYL)-3-HYDROXY-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE
    7-CHLORO-5-(2-CHLOROPHENYL)-3-HYDROXY-1H-1,4-BENZODIAZEPIN-2(3H)-ONE
    LS-34141
    TOLID
    LORAZON
    RATIOPHARM BRAND OF LORAZEPAM
    LORAZEPAMUM [INN-LATIN]
    LORAZEPAM-EFEKA
    NCGC00159439-02
    846-49-1
    DEMETHYLLORMETAZEPAM
    NOVOPHARM BRAND OF LORAZEPAM
    LORAFEN
    7-CHLORO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-2H-1,4-BENZODIAZEPIN-2-ONE
    LORAZEPAM RIEMSER BRAND
    SEDIZEPAN
    CT-ARZNEIMITTEL BRAND OF LORAZEPAM
    LORAZEPAM NU-PHARM BRAND
    LORAZEPAM RATIOPHARM
    BRN 0759084
    LORAZEPAM NOVARTIS BRAND
    AHP BRAND OF LORAZEPAM
    NSC289758
    SEDICEPAN
    BAXTER BRAND OF LORAZEPAM
    NU LORAZ
    RENAQUIL
    DONIX
    SILENCE
    LOPAM
    2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-, (+-)-
    MAX PAX
    ANZEPAM
    LORAZEP
    HMS2052H07
    ATIVAN (TN)
    LORAZEPAM FABRA
    SINESTRON
    DESITIN BRAND OF LORAZEPAM
    LORANS
    DURAZOLAM
    DEA NO. 2885
    LORAT
    APOTEX BRAND OF LORAZEPAM
    LORAZEPAM DOLORGIET BRAND
    LORIVAN
    SERRA PAMIES BRAND OF LORAZEPAM
    TRAPAX
    NU-LORAZ
    NOVO-LORAZEM
    LORAZEPAM NOVOPHARM BRAND
    ANXIRA
    CID3958
    TRANQIPAM
    APLACASSE
    LOZEPAM
    WYETH BRAND OF LORAZEPAM
    LORAM
    UNII-O26FZP769L
    MEDIX BRAND OF LORAZEPAM
    BONTON
    LORAZEPAM-NEURAXPHARM
    NU PHARM BRAND OF LORAZEPAM
    NEURAXPHARM BRAND OF LORAZEPAM
    LORAZEPAM CT-ARZNEIMITTEL BRAND
    SAM001246833
    MOLPORT-002-051-769
    5-25-02-00248 (BEILSTEIN HANDBOOK REFERENCE)
    ARIPAX
    EINECS 212-687-6
    2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(O-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-
    AZUROGEN
    NOVOLORAZEM
    NOVO LORAZEM
    NOVHEPAR
    LORAZEPAM APOTEX BRAND
    ORFIDAL
    LORAZEPAM MEDIX BRAND
    SIDENAR
    VIGITEN
    CHEBI:116959
    LORAZEPAM (ATIVAN)
    2H,1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(O-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-
    LORAZEPAN CHOBET
    NOVARTIS BRAND OF LORAZEPAM
    DURALOZAM
    EQUITAM
    MEDICAL, LORAZEPAM
    MEDICAL BRAND OF LORAZEPAM
    DOLORGIET BRAND OF LORAZEPAM
    MERLIT
    LORAZEPAM NEURAXPHARM BRAND
    LORAZEP VON CT
    CPD000058410
    WLN: T67 GMV JN IHJ CG IQ KR BG
    LORAZEPAM RATIOPHARM BRAND
    NINDS_000965
    MERCK DURA BRAND OF LORAZEPAM
    LORAZEPAM NEURAXPHARM
    APO LORAZEPAM
    STAPAM
    LORAZEPAMUM
    LORAZEPAM AHP BRAND
    ORFIDAL WYETH
    EMOTION
    LOMESTA
    NERVISTOPL
    D008140
    LORAZEPAM [USAN:INN:BAN:JAN]
    RIEMSER BRAND OF LORAZEPAM
    ROCOSGEN
    LLORENS BRAND OF LORAZEPAM
    LARPOSE
    7-CHLORO-5-(O-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-2H-1,4-BENZODIAZEPIN-2-ONE
    LAUBEEL
    LORENIN
    UPAN
    LORAZEPAM (JP15/USP/INN)
    LORAZEPAM DESITIN BRAND
    NULORAZ
    LORAPAM
    IDI1_000965
    LORIDEM
    LORAZEPAN RICHET
    NERVISTOP L
    LORSEDAL
    KALMALIN
    7-CHLORO-5-(2-CHLOROPHENYL)-3-HYDROXY-1,3-DIHYDRO-1,4-BENZODIAZEPIN-2-ONE
    WY 4036
    EFASEDAN
    CT ARZNEIMITTEL BRAND OF LORAZEPAM
    WY4036
    LORAZENE
    LORZEM
    KBIO1_000965
    AC1L1H3H
    (+-)-7-CHLORO-5-(O-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-2H-1,4-BENZODIAZEPIN-2-ONE
    LORAZEPAM LANNACHER
    NCHEMBIO747-COMP26
    178100785
    [11C]DOXEPIN
    178102508
    5884
    7-CHLORO-5-(2-CHLOROPHENYL)-3-HYDROXY-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE
    (R)-LORAZEPAM
    DIWRORZWFLOCLC-UHFFFAOYSA-N
    7-CHLORO-5-(2-CHLORO-PHENYL)-3-HYDROXY-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE (LORAZEPAM)
    (RS)-9-CHLORO-6-(2-CHLOROPHENYL)-4-HYDROXY-2,5-DIAZABICYCLO[5.4.0]UNDECA-5,8,10,12-TETRAEN-3-ONE
    LORAZEPAM7-CHLORO-5-(2-CHLORO-PHENYL)-3-HYDROXY-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE
    7-CHLORO-5-(2-CHLOROPHENYL)-3-HYDROXY-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE #
    7-CHLORO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-2H-1,4-BENZODIAZEPINE-2-ONE
    7-CHLORO-5-(2-CHLORO-PHENYL)-3-HYDROXY-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE
    7-CHLORO-3-HYDROXY-5-(2'-CHLOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPINE-2-ONE
    7-CHLORO-3-HYDROXY-5-(2'-CHLORO-PHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPINE-2-ONE
    7-CHLORANYL-5-(2-CHLOROPHENYL)-3-OXIDANYL-1,3-DIHYDRO-1,4-BENZODIAZEPIN-2-ONE
    2H-1, 7-CHLORO-5-(O-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-
    2H-1, 7-CHLORO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-
    I14-16542
    BRD-A11990600-001-01-8
    7-CHLORO-5-(O-CHLOROPHENYL)-1,4-BENZODIAZEPIN-2-ONE
    A840886
    FT-0670847
    SMR000058410
    SC-50855
    HE412111
    HE396247
    HE282111
    HE004691
    CAS-846-49-1
    AN-20537
    AK116454
    NSC-289758
    NC00420
    CCG-101170
    AKOS015904303
    BDBM50292627
    TOX21_111669
    HMS3394H07
    CTK3E8194
    GTPL5884
    LORAZEPAM (JP16/USP/INN)
    MLS001424236
    SCHEMBL26961
    DSSTOX_GSID_23225
    DSSTOX_RID_76932
    DSSTOX_CID_3225
    ATIVAN AND OTHERS
    ATIVANREG
    ORFIDALREG
    DPR000034
    46060463
    CYT-009-GHRQB
    9963889

    Drug Info:

    Drug Type drug/small molecule
    ATC n05ba(benzodiazepine derivatives)
    Drug Class anti-anxiety agents
    Year of Approval 1977
    Drug Class anticonvulsants
    Drug Class hypnotics and sedatives
    FDA Approval 1977
    Drug Class small molecule
    Drug Indications Hypnotics and Sedatives
    Drug Indications Anticonvulsants
    Drug Indications Anti-anxiety Agents
    FDA Approval not approved
    Drug Class vaccine
    Drug Indications appetite supressant,vaccine
    (7 More Sources)
  • Interaction Types:
    allosteric modulator

    Interaction Info:
    Specific Action of the Ligand Positive
    Details of Interaction lorazepam characterised as a non-selective GPR68 positive allosteric modulator for the agonist proton in cAMP production
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name -

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name CYT-009-GhrQb
    Novel drug target Novel Target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    Publications:

    • Version: 12-July-2012

    Alternate Names:
    C1CCC(C(C1)C2=NC(C(=O)NC3C2CC(CC3)CL)O)CL SMILES
    LORABENZ Drug Trade Name
    DB00186 drugBank

    Drug Info:
    ATC n05ba(benzodiazepine derivatives)
    Drug Type drug/small molecule

    Publications:

    • Version: 01-August-2011

    Alternate Names:

    Drug Info:
    Year of Approval 1977
    Drug Class anti-anxiety agents
    Drug Class hypnotics and sedatives

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications appetite supressant,vaccine
    Drug Class vaccine
    FDA Approval not approved

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Anti-anxiety Agents
    Drug Indications Anticonvulsants
    Drug Indications Hypnotics and Sedatives

    Publications:

    • Version: 14-September-2017
    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    NCHEMBIO747-COMP26 Drug Synonym
    LORAZEPAM LANNACHER Drug Synonym
    (+-)-7-CHLORO-5-(O-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-2H-1,4-BENZODIAZEPIN-2-ONE Drug Synonym

    Drug Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    178102508 PubChem Drug SID

    Drug Info:

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    CYT-009-GHRQB pubchem_primary_name
    9963889 PubChem CID
    DPR000034 Drug Synonym

    Drug Info:

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    ANZEPAM Drug Synonym
    3958 PubChem CID
    ATIVAN Drug Synonym

    Drug Info:

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    CYT-009-GHRQB Primary Drug Name
    46060463 Pubchem SId
    DPR000034 TTD Drug Id

    Drug Info:

    Publications:

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications: