DGIdb - LABETALOL Drug Record

LABETALOL CHEMBL429 FDA Approved

Alternate Names:

Labetalol
Trandate
Normozide
Normodyne
C29146
SPECTRUM_001607
NCGC00089800-02
PRESTWICK3_000277
C07063
SPECTRUM5_001010
3869
KBIOGR_000727
LABETALOLUM
LABETALOLUM [INN-LATIN]
PRESTWICK1_000277
KBIO2_002087
AB00053659
LABETOLOL
IDI1_000474
DB00598
2-HYDROXY-5-{1-HYDROXY-2-[(1-METHYL-3-PHENYLPROPYL)AMINO]ETHYL}BENZAMIDE
KBIO2_004655
2-HYDROXY-5-[1-HYDROXY-2-(4-PHENYLBUTAN-2-YLAMINO)ETHYL]BENZAMIDE
AC-18747
BENZAMIDE, 2-HYDROXY-5-[1-HYDROXY-2-[(1-METHYL-3-PHENYLPROPYL)AMINO]ETHYL]-
BPBIO1_000170
3-CARBOXAMIDO-4-HYDROXY-ALPHA-((1-METHYL-3-PHENYLPROPYLAMINO)METHYL)BENZYL ALCOHOL
D08106
LABETALOL (INN)
BSPBIO_000154
IBIDOMIDE
PRESTWICK2_000277
EINECS 253-258-3
SPECTRUM4_000184
BSPBIO_003142
KBIO3_002642
CID3869
KBIO2_007223
9275
UNII-R5H8897N95
NINDS_000474
MOLPORT-003-898-140
CHEBI:6343
TL8002725
KBIOSS_002087
NCGC00015595-06
SCH-19927
HSDB 6537
BRD-A07440155-003-05-6
2-HYDROXY-5-(1-HYDROXY-2-((1-METHYL-3-PHENYLPROPYL)AMINO)ETHYL)BENZAMIDE
AH-5158
SPECTRUM3_001581
SPECTRUM2_000863
BENZAMIDE, 2-HYDROXY-5-(1-HYDROXY-2-((1-METHYL-3-PHENYLPROPYL)AMINO)ETHYL)-
DAP000038
LABETALOL [INN:BAN]
5-(1-HYDROXY-2-(1-METHYL-3-PHENYLPROPYLAMINO)ETHYL)SALICYLAMIDE
36894-69-6
PRESTWICK0_000277
AC1L1GW8
SBB067266
LOPAC0_000687
AH 5158
KBIO1_000474
L001344
SPBIO_002373
ALBETOL
DIVK1C_000474
LS-26936
SPBIO_000905
BENZAMIDE,2-HYDROXY-5-[(1R)-1-HYDROXY-2-[[(1S)-1-METHYL-3-PHENYLPROPYL]AMINO]ETHYL]-,REL-
3-CARBOXAMIDO-4-HYDROXY-.ALPHA.-((1-METHYL-3-PHENYLPROPYLAMINO)METHYL)BENZYL ALCOHOL
2-HYDROXY-5-{1-HYDROXY-2-[(4-PHENYLBUTAN-2-YL)AMINO]ETHYL}BENZENE-1-CARBOXIMIDIC ACID
Q-201273
FT-0630598
KB-230863
U685
OR333390
OR263607
OR067997
BC214322
AK116436
NCGC00015595-07
NCGC00015595-04
NCGC00015595-03
R5H8897N95
MCULE-6427232261
CCG-204772
AKOS015908406
83167-32-2
83167-24-2
LABETALOL HYDROCHLORIDE (SALT/MIX)
SGUAFYQXFOLMHL-UHFFFAOYSA-N
2-HYDROXY-5-[(1S)-1-HYDROXY-2-{[(2S)-4-PHENYLBUTAN-2-YL]AMINO}ETHYL]BENZAMIDE
BDBM25758
GTPL7207
SCHEMBL4582
NORMODYNE (SALT/MIX)
TRANDATE (SALT/MIX)
AMIPRESS (SALT/MIX)
2-HYDROXY-5-{1-HYDROXY-2-[(4-PHENYLBUTAN-2-YL)AMINO]ETHYL}BENZAMIDE
2-HYDROXY-5-(1-HYDROXY-2-[(1-METHYL-3-PHENYLPROPYL)AMINO]ETHYL)BENZAMIDE
TRANDATEREG
NORMODYNEREG
SCH 15719W
2-HYDROXY-5-(1-HYDROXY-2-((4-PHENYLBUTAN-2-YL)AMINO)ETHYL)BENZAMIDE
178100706
D[VAL4,DARG8]VP
178103782
7207

Drug Info:

FDA Approval	1984
Drug Class	small molecule
Drug Indications	Antihypertensive Agents
Year of Approval	1984
Drug Class	antihypertensive agents

(3 More Sources)

Publications:

Yeh et al., 2006, Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment., Am. J. Hypertens.
Hylander et al., 1985, Effects of long-term therapy with labetalol on lipoprotein metabolism in patients with mild hypertension., Acta Med Scand

LABETALOL AVPR2

Interaction Types:

agonist

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Direct Interaction? False

Publications:
LABETALOL ADRB2

Interaction Types:

antagonist

Interaction Info:

Trial Name -

Novel drug target Established target

Specific Action of the Ligand Antagonist

Publications:
LABETALOL ADRA1A

Interaction Types:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

Publications:
LABETALOL ADRB1

Interaction Types:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

Publications:
LABETALOL ADRA1B

Interaction Types:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

Publications:
LABETALOL GJA1

Interaction Types:

n/a

Interaction Info:

Publications:

Yeh et al., 2006, Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment., Am. J. Hypertens.
LABETALOL LPL

Interaction Types:

n/a

Interaction Info:

Publications:

Hylander et al., 1985, Effects of long-term therapy with labetalol on lipoprotein metabolism in patients with mild hypertension., Acta Med Scand

TEND: LABETALOL
- Version: 01-August-2011
Alternate Names:

LABETALOL Primary Drug Name

Drug Info:

Drug Class antihypertensive agents

Year of Approval 1984

Publications:
TdgClinicalTrial: LABETALOL
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Antihypertensive Agents

Drug Class small molecule

FDA Approval 1984

Publications:

NCI: LABETALOL

Version: 14-September-2017

Alternate Names:

C29146 NCI drug code

Drug Info:

Publications:

Yeh et al., 2006, Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment., Am. J. Hypertens.

Hylander et al., 1985, Effects of long-term therapy with labetalol on lipoprotein metabolism in patients with mild hypertension., Acta Med Scand

TTD: DAP000038
- Version: 4.3.02 (25-August-2011)
Alternate Names:

LABETALOL Primary Drug Name

SPBIO_000905 Drug Synonym

LS-26936 Drug Synonym

Drug Info:

Publications:
PubChem: LABETALOL
- Version: 09-Feb-2016
Alternate Names:

LABETALOL pubchem_primary_name

3869 PubChem CID

LABETOLOL Drug Synonym

Drug Info:

Publications:
GuideToPharmacologyInteractions: 7207
- Version: 27-September-2017
Alternate Names:

LABETALOL GuideToPharmacology Ligand Name

178103782 PubChem Drug SID

Drug Info:

Publications:
GuideToPharmacologyInteractions: 3869
- Version: 27-September-2017
Alternate Names:

D[VAL4,DARG8]VP GuideToPharmacology Ligand Name

178100706 PubChem Drug SID

Drug Info:

Publications:

Specific Action of the Ligand	Full agonist
Endogenous Drug?	False
Direct Interaction?	False

Trial Name	-
Novel drug target	Established target
Specific Action of the Ligand	Antagonist

LABETALOL	Primary Drug Name
SPBIO_000905	Drug Synonym
LS-26936	Drug Synonym

LABETALOL	pubchem_primary_name
3869	PubChem CID
LABETOLOL	Drug Synonym

LABETALOL	GuideToPharmacology Ligand Name
178103782	PubChem Drug SID

LABETALOL Drug Record

LABETALOL CHEMBL429 FDA Approved

Alternate Names:

Drug Info:

Publications:

LABETALOL AVPR2

Interaction Types: agonist

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False Direct Interaction? False

Publications:

LABETALOL ADRB2

Interaction Types: antagonist

Interaction Info: Trial Name - Novel drug target Established target Specific Action of the Ligand Antagonist

Publications:

LABETALOL ADRA1A

Interaction Types: n/a

Interaction Info: Trial Name - Novel drug target Established target

Publications:

LABETALOL ADRB1

Interaction Types: n/a

Interaction Info: Trial Name - Novel drug target Established target

Publications:

LABETALOL ADRA1B

Interaction Types: n/a

Interaction Info: Trial Name - Novel drug target Established target

Publications:

LABETALOL GJA1

Interaction Types: n/a

Interaction Info:

Publications: Yeh et al., 2006, Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment., Am. J. Hypertens.

LABETALOL LPL

Interaction Types: n/a

Interaction Info:

Publications: Hylander et al., 1985, Effects of long-term therapy with labetalol on lipoprotein metabolism in patients with mild hypertension., Acta Med Scand

TEND: LABETALOL

Alternate Names: LABETALOL Primary Drug Name

Drug Info: Drug Class antihypertensive agents Year of Approval 1984

Publications:

TdgClinicalTrial: LABETALOL

Alternate Names:

Drug Info: Drug Indications Antihypertensive Agents Drug Class small molecule FDA Approval 1984

Publications:

NCI: LABETALOL

Alternate Names: C29146 NCI drug code

Drug Info:

TTD: DAP000038

Alternate Names: LABETALOL Primary Drug Name SPBIO_000905 Drug Synonym LS-26936 Drug Synonym

Drug Info:

Publications:

PubChem: LABETALOL

Alternate Names: LABETALOL pubchem_primary_name 3869 PubChem CID LABETOLOL Drug Synonym

Drug Info:

Publications:

GuideToPharmacologyInteractions: 7207

Alternate Names: LABETALOL GuideToPharmacology Ligand Name 178103782 PubChem Drug SID

Drug Info:

Publications:

GuideToPharmacologyInteractions: 3869

Alternate Names: D[VAL4,DARG8]VP GuideToPharmacology Ligand Name 178100706 PubChem Drug SID

Drug Info:

Publications:

Interaction Types:

agonist

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Direct Interaction? False

Interaction Types:

antagonist

Interaction Info:

Trial Name -

Novel drug target Established target

Specific Action of the Ligand Antagonist

Interaction Types:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

Interaction Types:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

Interaction Types:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

Interaction Types:

n/a

Publications:

Yeh et al., 2006, Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment., Am. J. Hypertens.

Interaction Types:

n/a

Publications:

Hylander et al., 1985, Effects of long-term therapy with labetalol on lipoprotein metabolism in patients with mild hypertension., Acta Med Scand

Alternate Names:

LABETALOL Primary Drug Name

Drug Info:

Drug Class antihypertensive agents

Year of Approval 1984

Drug Info:

Drug Indications Antihypertensive Agents

Drug Class small molecule

FDA Approval 1984

Alternate Names:

C29146 NCI drug code

Alternate Names:

LABETALOL Primary Drug Name

SPBIO_000905 Drug Synonym

LS-26936 Drug Synonym

Alternate Names:

LABETALOL pubchem_primary_name

3869 PubChem CID

LABETOLOL Drug Synonym

Alternate Names:

LABETALOL GuideToPharmacology Ligand Name

178103782 PubChem Drug SID

Alternate Names:

D[VAL4,DARG8]VP GuideToPharmacology Ligand Name

178100706 PubChem Drug SID