• ISTRADEFYLLINE CHEMBL431770

    Alternate Names:

    Istradefylline
    KW-6002
    1H-PURINE-2,6-DIONE, 3,7-DIHYDRO-1,3-DIETHYL-8-(2-(3,4-DIMETHOXYPHENYL)ETHENYL)-7-METHYL-, (E)-
    8-[(E)-2-(3,4-DIMETHOXYPHENYL)ETHENYL]-1,3-DIETHYL-7-METHYLPURINE-2,6-DIONE
    LS-126708
    CHEBI:222252
    155270-99-8
    1H-PURINE-2,6-DIONE, 8-((1E)-2-(3,4-DIMETHOXYPHENYL)ETHENYL)-1,3-DIETHYL-3,7-DIHYDRO-7-METHYL-
    8-((1E)-2-(3,4-DIMETHOXYPHENYL)ETHENYL)-1,3-DIETHYL-7-METHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE
    12014869
    AC1NSJVH
    5311037
    CID5311037
    ISTRADEFYLLINE (JAN/USAN/INN)
    (E)-8-(3,4-DIMETHOXYSTYRYL)-1,3-DIETHYL-7-METHYLXANTHINE
    D04641
    (E)-8-(3,4-DIMETHOXYSTYRYL)-1,3-DIETHYL-7-METHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE
    8-(2-(3,4-DIMETHOXYPHENYL)ETHENYL)-1,3-DIETHYL-3,7-DIHYDRO-7-METHYL-1H-PURINE-2,6-DIONE
    DCL000312
    ISTRADEFYLLINE [USAN:INN]
    L001483
    UNII-2GZ0LIK7T4
    C111599
    KW 6002
    8-[(E)-2-(3,4-DIMETHOXY-PHENYL)-VINYL]-1,3-DIETHYL-7-METHYL-3,7-DIHYDRO-PURINE-2,6-DIONE
    8-[(1E)-2-(2-(3,4-DIMETHOXYPHENYL)ETHENYL]-1,3-DIETHYL-3,7-DIHYDRO-7-METHYL-1H-PURINE-2,6-DIONE
    1H-PURINE-2,6-DIONE,8-[(1E)-2-(3,4-DIMETHOXYPHENYL)ETHENYL]-1,3-DIETHYL-3,7-DIHYDRO-7-METHYL-
    8-[2-(3,4-DIMETHOXY-PHENYL)-VINYL]-1,3-DIETHYL-7-METHYL-3,9-DIHYDRO-PURINE-2,6-DIONE
    8-[2-(3,4-DIMETHOXY-PHENYL)-VINYL]-1,3-DIETHYL-7-METHYL-3,7-DIHYDRO-PURINE-2,6-DIONE
    8-[(E)-2-(3,4-DIMETHOXYPHENYL)VINYL]-1,3-DIETHYL-7-METHYL-PURINE-2,6-DIONE
    8-(E)-2-(3,4-DIMETHOXYPHENYL)ETHENYL-1,3-DIETHYL-7-METHYL-PURINE-2,6-DIONE
    8-(3,4-DIMETHOXYSTYRYL)-1,3-DIETHYL-7-METHYL-1H-PURINE-2,6(3H,7H)-DIONE
    (E)- 8-(3,4-DIMETHOXYSTYRYL)-1,3-DIETHYL-7-METHYLXANTHINE
    1,3-DIETHYL-7-METHYL-8-(3,4-DIMETHOXYSTYRYL)XANTHINE
    Z4210
    FT-0686956
    CAS-155270-99-8
    4CH-010275
    AB0069237
    SMR004701638
    HY-10888
    HE314531
    HE065946
    CJ-10766
    AK-43718
    AJ-45656
    VA11117
    RL01993
    MP-2039
    CS-0737
    BCP9000824
    AM84508
    AKOS015966268
    IN2171
    EBD235277
    DNC005809
    DCL000460
    BDBM50176050
    AN-481
    TOX21_113855
    ZINC3803921
    MOLPORT-035-395-095
    MOLPORT-020-007-387
    IQVRBWUUXZMOPW-PKNBQFBNSA-N
    AOB2515
    ISTRADEFYLLINE [USAN:INN:JAN]
    GTPL5608
    SCHEMBL633263
    SCHEMBL633262
    MLS006010633
    DSSTOX_GSID_57652
    DSSTOX_RID_97327
    DSSTOX_CID_31441
    2GZ0LIK7T4
    ISTRADEFYLLINE KW 6002
    NOURIAST (TN)
    NCGC00253737-01
    KW6002
    ISTRADEFYLLINE (KW-6002)
    8-[(E)-2-(3,4-DIMETHOXYPHENYL)ETHENYL]-1,3-DIETHYL-7-METHYL-PURINE-2,6 -DIONE
    KB-46604
    (E)-8-(3,4-DIMETHOXYSTYRYL)-1,3-DIETHYL-7-METHYL-1H-PURINE-2,6(3H,7H)-DIONE
    178102242
    5608

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications antiparkinson agent
    (1 More Sources)

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Mechanism of Interaction Adenosine A2a receptor antagonist
    Direct Interaction yes
    Specific Action of the Ligand Antagonist

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Trial Name istradefylline, KW-6002
    Novel drug target Established target
    Specific Action of the Ligand Antagonist

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antiparkinson agent
    Drug Class Small molecule
    FDA Approval not approved

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    KW 6002 Drug Synonym
    155270-99-8 CAS Number
    C111599 Drug Synonym

    Drug Info:

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    MLS006010633 Drug Synonym
    L001483 Drug Synonym
    ISTRADEFYLLINE pubchem_primary_name

    Drug Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    ISTRADEFYLLINE GuideToPharmacology Ligand Name
    178102242 PubChem Drug SID

    Drug Info:

    Publications:

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications: