Flumazenil |
Ro-151788000 |
Flumazepil |
Romazicon |
Mazicon |
Anexate |
Ro-151788 |
Lanexat |
Jamp-flumazenil |
Flumazenil Injection, USP |
Flumazenil Injection Sdz |
Flumazenil Injection |
Anexate Inj 0.1mg/ml |
78755-81-4 |
DB01205 |
NCGC00025116-04 |
NCGC00015439-01 |
CID3373 |
LOPAC-F-6300 |
UNII-40P7XK9392 |
MLS001076354 |
FLUMAZENILO |
S1332_SELLECK |
NCGC00015439-03 |
AC1L1FSE |
HMS2089B15 |
AC1Q33UE |
NCGC00025116-05 |
FLUMAZEPIL, RO 15-1788, ANEXATE, LANEXAT, MAZICON, ROMA,FLUMAZENIL |
FLUMAZENILUM |
BPBIO1_001190 |
SBB063113 |
NCGC00025116-02 |
NCGC00025116-01 |
TOCRIS-1328 |
PDSP1_001778 |
SMR000058450 |
ZINC00001464 |
FLUMAZENIL [USAN:BAN:INN] |
4H-IMIDAZO(1,5-A)(1,4)BENZODIAZEPINE-3-CARBOXYLIC ACID, 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-, ETHYL ESTER |
LOPAC0_000506 |
UPCMLD-DP137 |
MLS000028850 |
ETHYL 8-FLUORO-5-METHYL-6-OXO-5,6-DIHYDRO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLATE |
D005442 |
CPD000058450 |
BRN 4763661 |
TL8005362 |
F6300_SIGMA |
MOLPORT-003-666-855 |
BRD-K98769987-001-01-3 |
PDSP2_001761 |
CHEBI:5103 |
MLS000759529 |
10027 |
3373 |
I01-0379 |
ROMAZICON (TN) |
HMS2051D17 |
[3H]RO15-1788 |
NCGC00015439-07 |
UPCMLD-DP137:001 |
ETHYL 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO(1,5-A)(1,4)BENZODIAZEPINE-3-CARBOXYLATE |
HOFFMAN LA ROCHE BRAND OF FLUMAZENIL |
ROCHE BRAND OF FLUMAZENIL |
F 6300 |
LS-77778 |
C15H14FN3O3 |
8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID ETHYL ESTER |
DAP000685 |
FLUMAZENIL (JAN/USP/INN) |
NCGC00025116-03 |
HOFFMAN-LA ROCHE BRAND OF FLUMAZENIL |
EU-0100506 |
BIOMOL-NT_000285 |
FLUMAZENILO [SPANISH] |
SAM001246763 |
ETHYL 8-FLUORO-5-METHYL-5,6-DIHYDRO-6-OXO-4H-IMIDAZO(1,5-A)(1,4)BENZODIAZEPINE-3-CARBOXYLATE |
D00697 |
BIDD:GT0766 |
FLUMAZENILUM [LATIN] |
AC-6846 |
C07825 |
ETHYL 8-FLUORO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLATE |
NCHEMBIO747-COMP37 |
178101009 |
4192 |
AOB5595 |
CTK8F9785 |
BDBM26263 |
[11C]FLUMAZENIL (PET LIGAND) |
FLUMAZENIL (RO 15-1788) |
ZINC1464 |
IMI061 |
GTPL4367 |
GTPL4192 |
MLS001424108 |
SCHEMBL79030 |
4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID, 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-, ETHYL ESTER |
[11C]FLUMAZENIL |
FLUMAZIL |
ANEXATEREG |
FUMAZENIL |
CAS-78755-81-4 |
ETHYL 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLATE |
DSSTOX_GSID_23064 |
DSSTOX_RID_76860 |
DSSTOX_CID_3064 |
NCGC00015439-06 |
OFBIFZUFASYYRE-UHFFFAOYSA-N |
ETHYL 8-FLUORO-5-METHYL-6-OXO-5,6-DIHYDRO-4H-BENZO[F]IMIDAZO[1,5-A][1,4]DIAZEPINE-3-CARBOXYLATE |
ETHYL 8-FLUORO-5-METHYL-6-OXO-5,6-DIHYDRO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLATE # |
ETHYL 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPIN-3-CARBOXYLATE |
ETHYL 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]-BENZODIAZEPINE-3-CARBOXYLATE |
ETHYL 8-FLUORANYL-5-METHYL-6-OXIDANYLIDENE-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLATE |
ETHYL 12-FLUORO-8-METHYL-9-OXO-2,4,8-TRIAZATRICYCLO[8.4.0.0^{2,6}]TETRADECA-1(14),3,5,10,12-PENTAENE-5-CARBOXYLATE |
ETHYL 12-FLUORO-8-METHYL-9-OXO-2,4,8-TRIAZATRICYCLO[8.4.0.0?,?]TETRADECA-1(10),3,5,11,13-PENTAENE-5-CARBOXYLATE |
ETHYL 12-FLUORO-8-METHYL-9-OXO-2,4,8-TRIAZATRICYCLO[8.4.0.0;{2,6}]TETRADECA-1(10),3,5,11,13-PENTAENE-5-CARBOXYLATE |
ETHYL 12-FLUORO-8-METHYL-9-OXO-2,4,8-TRIAZATRICYCLO[8.4.0.0(2),?]TETRADECA-1(10),3,5,11,13-PENTAENE-5-CARBOXYLATE |
8-FLUORO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID ETHYL ESTER |
8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID, ETHYL ESTER |
FLUMAZEPIL;RO 15-1788;ANEXATE;LANEXAT;MAZICON;ROMA |
Q-201122 |
3B2-0921 |
A839484 |
AB00572626-13 |
AB00572626-12 |
W-5096 |
RO-15-1788/000 |
RO 15-1788/000 |
ST24047162 |
FT-0630863 |
F0958 |
AB2000052 |
AB0014201 |
ZB000344 |
PL069864 |
K393 |
DR001229 |
AK140079 |
AJ-08034 |
NCGC00015439-11 |
NCGC00015439-09 |
NCGC00015439-08 |
NCGC00015439-05 |
NCGC00015439-04 |
NCGC00015439-02 |
FLUMAZENIL-SUPPLIED BY SELLECK CHEMICALS |
NSC-759193 |
NC00218 |
MCULE-2830706565 |
LP00506 |
CS-0629 |
CCG-100968 |
AN-6313 |
40P7XK9392 |
TOX21_110148_1 |
AKOS015888159 |
NSC759193 |
TOX21_110148 |
HY-B0009 |
FLUMAZENIL [USAN:USP:INN:BAN] |
PHARMAKON1600-01505701 |
HMS3393D17 |
HMS3374E10 |
HMS3267P09 |
HMS3261F13 |
HMS2234F06 |
178101182 |
4367 |
Drug Categories | specialty uses of chemicals |
Drug Categories | protective agents |
Drug Categories | physiological effects of drugs |
Drug Categories | pharmacologic actions |
Drug Categories | neurotransmitter agents |
Drug Categories | molecular mechanisms of pharmacological action |
Drug Categories | heterocyclic compounds, 2-ring |
Drug Categories | heterocyclic compounds |
Drug Categories | gaba modulators |
Drug Categories | gaba agents |
Drug Categories | chemical actions and uses |
Drug Categories | benzodiazepinones |
Drug Categories | benzodiazepines |
Drug Categories | benzazepines |
Drug Categories | antidotes |
Drug Groups | approved |
Drug Type | small molecule |
Drug Class | antidotes, benzodoazepine overdose |
Year of Approval | 1991 |
FDA Approval | 1991 |
Drug Class | small molecule |
Drug Indications | Antidotes, Benzodoazepine Overdose |
antagonist |
allosteric modulator |
positive allosteric modulator |
Specific Binding Site for Interaction | benzodiazepine site |
Details of the Assay for Interaction | Affinity measured using α1β3γ2 receptors. |
Specific Action of the Ligand | Antagonist |
antagonist |
allosteric modulator |
Specific Binding Site for Interaction | benzodiazepine site |
Details of the Assay for Interaction | Affinity measured using α5β3γ2 receptors. |
Specific Action of the Ligand | Antagonist |
allosteric modulator |
Trial Name | - |
Novel drug target | Established target |
Specific Binding Site for Interaction | benzodiazepine site |
allosteric modulator |
Specific Binding Site for Interaction | benzodiazepine site |
Details of the Assay for Interaction | Affinity measured using α3β3γ2 receptors. |
Specific Action of the Ligand | Antagonist |
allosteric modulator |
Specific Binding Site for Interaction | benzodiazepine site |
Specific Action of the Ligand | Partial agonist |
Details of Interaction | low affinity |
allosteric modulator |
Specific Binding Site for Interaction | benzodiazepine site |
Specific Action of the Ligand | Partial agonist |
Details of Interaction | low affinity |
antagonist |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
n/a |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel allosteric antagonist |
Direct Interaction | yes |
FLUMAZENIL | DrugBank Drug Name |
Anexate | Drug Synonym |
Flumazepil | Drug Synonym |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | antidotes |
FLUMAZENIL | Primary Drug Name |
Year of Approval | 1991 |
Drug Class | antidotes, benzodoazepine overdose |
Drug Indications | Antidotes, Benzodoazepine Overdose |
Drug Class | small molecule |
FDA Approval | 1991 |
FLUMAZENIL | GuideToPharmacology Ligand Name |
178101009 | PubChem Drug SID |
[11C]FLUMAZENIL | GuideToPharmacology Ligand Name |
178101182 | PubChem Drug SID |
NCHEMBIO747-COMP37 | Drug Synonym |
ETHYL 8-FLUORO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLATE | Drug Synonym |
C07825 | Drug Synonym |
LANEXAT | Drug Synonym |
MAZICON | Drug Synonym |
FLUMAZENIL | pubchem_primary_name |