DGIdb - FENOLDOPAM Drug Record

FENOLDOPAM CHEMBL588 FDA Approved

Alternate Names:

Fenoldopam
SK-82526
SK&F-82526
Corlopam
67227-56-9
DB00800
AC1Q3LHG
CARLACOR
BIOMOL-NT_000042
67227-57-0
LS-27993
NCGC00025246-02
BPBIO1_001265
PDSP1_001661
FENOLDOPAM (INN)
NCGC00025246-03
6-CHLORO-1-(4-HYDROXYPHENYL)-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE-7,8-DIOL
FENODOPAM MESYLATE
67287-54-1 (HYDROBROMIDE)
3341
188303
CHEBI:5002
DAP000254
67227-57-0 (MESYLATE)
HMS2090G16
LOPAC0_000556
FENOLDOPAMUM [LATIN]
NCGC00015444-05
9-CHLORO-5-(4-HYDROXYPHENYL)-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE-7,8-DIOL
L000254
CARLACOR (TN)
UNII-INU8H2KAWG
C07693
87900-90-1
PDSP2_001645
FENOLDOPAM [INN:BAN]
1H-3-BENZAZEPINE-7,8-DIOL, 6-CHLORO-2,3,4,5-TETRAHYDRO-1-(4-HYDROXYPHENYL)-
AR-1L4264
AC1L1FPQ
D07946
CID3341
BRD-A50684349-001-01-5
FENOLDOPAMUM
135651054
939
9-CHLORO-5-(4-HYDROXYPHENYL)-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE-7,8-DIOL;METHANESULFONIC ACID
9-CHLORANYL-5-(4-HYDROXYPHENYL)-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE-7,8-DIOL;METHANESULFONIC ACID
9-CHLORO-5-(4-HYDROXYPHENYL)-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE-7,8-DIOL;MESYLIC ACID
AB00698256-15
AB00698256-13
FT-0641107
AB2000493
AB0013872
I745
BC220528
AN-38412
NCGC00015444-07
NCGC00015444-06
NCGC00015444-03
VA10891
MCULE-7876003953
CS-2979
CCG-204646
TOX21_110152_1
AKOS015906543
TOX21_110152
HY-B0735
BDBM60917
SCHEMBL13287212
CID_49659
GTPL939
SCHEMBL34250
CORLOPAMREG
SMR000469190
SK-82526-J
CAS-67227-56-9
MLS001401388
DSSTOX_GSID_43896
DSSTOX_RID_80083
DSSTOX_CID_23896
NCGC00015444-04
TVURRHSHRRELCG-UHFFFAOYSA-N

Drug Info:

Drug Categories	vasodilator agents
Drug Categories	therapeutic uses
Drug Categories	physiological effects of drugs
Drug Categories	pharmacologic actions
Drug Categories	neurotransmitter agents
Drug Categories	molecular mechanisms of pharmacological action
Drug Categories	hypotensive agents
Drug Categories	heterocyclic compounds, 2-ring
Drug Categories	heterocyclic compounds
Drug Categories	dopamine agonists
Drug Categories	dopamine agents
Drug Categories	chemical actions and uses
Drug Categories	cardiovascular system
Drug Categories	cardiovascular agents
Drug Categories	cardiac therapy
Drug Categories	cardiac stimulants excl. cardiac glycosides
Drug Categories	benzazepines
Drug Categories	antihypertensive agents
Drug Categories	adrenergic and dopaminergic agents
Drug Groups	approved
Drug Type	small molecule
Drug Class	antihypertensive agents
Year of Approval	1997
FDA Approval	approved
Drug Class	Small Molecule
Drug Indications	antihypertensive agent

(2 More Sources)

Publications:

Zeng et al., 2009, D1-like receptors inhibit insulin-induced vascular smooth muscle cell proliferation via down-regulation of insulin receptor expression., J. Hypertens.
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Dhasmana et al., The role of dopamine (D2), alpha and beta-adrenoceptor receptors in the decrease in gastrointestinal transit induced by dopamine and dopamine-related drugs in the rat., Pharmacol. Res.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

FENOLDOPAM DRD1

Interaction Types:

agonist

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Direct Interaction? True

Publications:

Zeng et al., 2009, D1-like receptors inhibit insulin-induced vascular smooth muscle cell proliferation via down-regulation of insulin receptor expression., J. Hypertens.

Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

Dhasmana et al., The role of dopamine (D2), alpha and beta-adrenoceptor receptors in the decrease in gastrointestinal transit induced by dopamine and dopamine-related drugs in the rat., Pharmacol. Res.

FENOLDOPAM DRD4

Interaction Types:

agonist

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Publications:

FENOLDOPAM DRD5

Interaction Types:

agonist

Interaction Info:

Trial Name fenoldopam mesylate, SKF-82526,Corlopam

Novel drug target Established target

Publications:

Zeng et al., 2009, D1-like receptors inhibit insulin-induced vascular smooth muscle cell proliferation via down-regulation of insulin receptor expression., J. Hypertens.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

FENOLDOPAM ADRA2B

Interaction Types:

antagonist

Interaction Info:

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

FENOLDOPAM ADRA2C

Interaction Types:

antagonist

Interaction Info:

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

FENOLDOPAM ADRA2A

Interaction Types:

antagonist

Interaction Info:

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

FENOLDOPAM ADRA1B

Interaction Types:

n/a

Interaction Info:

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.
FENOLDOPAM ADRA1D

Interaction Types:

n/a

Interaction Info:

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.
FENOLDOPAM ADRA1A

Interaction Types:

n/a

Interaction Info:

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

DrugBank: DB00800

Version: 5.0.8

Alternate Names:

FENOLDOPAM DrugBank Drug Name

67227-56-9 CAS Number

Corlopam Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories adrenergic and dopaminergic agents

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

TEND: FENOLDOPAM
- Version: 01-August-2011
Alternate Names:

FENOLDOPAM Primary Drug Name

Drug Info:

Year of Approval 1997

Drug Class antihypertensive agents

Publications:
TdgClinicalTrial: FENOLDOPAM
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications antihypertensive agent

Drug Class Small Molecule

FDA Approval approved

Publications:
TTD: DAP000254
- Version: 4.3.02 (25-August-2011)
Alternate Names:

FENOLDOPAMUM Drug Synonym

BRD-A50684349-001-01-5 Drug Synonym

DB00800 Drug Synonym

Drug Info:

Publications:
GuideToPharmacologyInteractions: 939
- Version: 27-September-2017
Alternate Names:

FENOLDOPAM GuideToPharmacology Ligand Name

135651054 PubChem Drug SID

Drug Info:

Publications:
PubChem: FENOLDOPAM
- Version: 09-Feb-2016
Alternate Names:

FENOLDOPAM pubchem_primary_name

3341 PubChem CID

FENOLDOPAMUM Drug Synonym

Drug Info:

Publications:

Specific Action of the Ligand	Full agonist
Endogenous Drug?	False
Direct Interaction?	True

Trial Name	fenoldopam mesylate, SKF-82526,Corlopam
Novel drug target	Established target

FENOLDOPAM	DrugBank Drug Name
67227-56-9	CAS Number
Corlopam	Drug Brand

FENOLDOPAMUM	Drug Synonym
BRD-A50684349-001-01-5	Drug Synonym
DB00800	Drug Synonym

FENOLDOPAM	GuideToPharmacology Ligand Name
135651054	PubChem Drug SID

FENOLDOPAM	pubchem_primary_name
3341	PubChem CID
FENOLDOPAMUM	Drug Synonym

FENOLDOPAM Drug Record

FENOLDOPAM CHEMBL588 FDA Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types: agonist

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False Direct Interaction? True

Interaction Types: agonist

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

Publications:

Interaction Types: agonist

Interaction Info: Trial Name fenoldopam mesylate, SKF-82526,Corlopam Novel drug target Established target

Interaction Types: antagonist

Interaction Info:

Interaction Types: antagonist

Interaction Info:

Interaction Types: antagonist

Interaction Info:

Interaction Types: n/a

Interaction Info:

Publications: Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Interaction Types: n/a

Interaction Info:

Publications: Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Interaction Types: n/a

Interaction Info:

Publications: Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

DrugBank: DB00800

Alternate Names: FENOLDOPAM DrugBank Drug Name 67227-56-9 CAS Number Corlopam Drug Brand

Drug Info: Drug Type small molecule Drug Groups approved Drug Categories adrenergic and dopaminergic agents

TEND: FENOLDOPAM

Alternate Names: FENOLDOPAM Primary Drug Name

Drug Info: Year of Approval 1997 Drug Class antihypertensive agents

Publications:

TdgClinicalTrial: FENOLDOPAM

Alternate Names:

Drug Info: Drug Indications antihypertensive agent Drug Class Small Molecule FDA Approval approved

Publications:

TTD: DAP000254

Alternate Names: FENOLDOPAMUM Drug Synonym BRD-A50684349-001-01-5 Drug Synonym DB00800 Drug Synonym

Drug Info:

Publications:

GuideToPharmacologyInteractions: 939

Alternate Names: FENOLDOPAM GuideToPharmacology Ligand Name 135651054 PubChem Drug SID

Drug Info:

Publications:

PubChem: FENOLDOPAM

Alternate Names: FENOLDOPAM pubchem_primary_name 3341 PubChem CID FENOLDOPAMUM Drug Synonym

Drug Info:

Publications:

Interaction Types:

agonist

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Direct Interaction? True

Interaction Types:

agonist

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Interaction Types:

agonist

Interaction Info:

Trial Name fenoldopam mesylate, SKF-82526,Corlopam

Novel drug target Established target

Interaction Types:

antagonist

Interaction Types:

antagonist

Interaction Types:

antagonist

Interaction Types:

n/a

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Interaction Types:

n/a

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Interaction Types:

n/a

Publications:

Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

Alternate Names:

FENOLDOPAM DrugBank Drug Name

67227-56-9 CAS Number

Corlopam Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories adrenergic and dopaminergic agents

Alternate Names:

FENOLDOPAM Primary Drug Name

Drug Info:

Year of Approval 1997

Drug Class antihypertensive agents

Drug Info:

Drug Indications antihypertensive agent

Drug Class Small Molecule

FDA Approval approved

Alternate Names:

FENOLDOPAMUM Drug Synonym

BRD-A50684349-001-01-5 Drug Synonym

DB00800 Drug Synonym

Alternate Names:

FENOLDOPAM GuideToPharmacology Ligand Name

135651054 PubChem Drug SID

Alternate Names:

FENOLDOPAM pubchem_primary_name

3341 PubChem CID

FENOLDOPAMUM Drug Synonym