• FAMOTIDINE CHEMBL902 FDA Approved

    Alternate Names:

    Famotidine
    Pepcid
    MK-208
    Fluxid
    Pepcid Rpd
    Pepcid Ac
    C29045
    MLS000758205
    MLS000028583
    BSPBIO_000088
    LOPAC0_000497
    LOPAC-F-6889
    PRESTWICK3_000104
    PRESTWICK2_000104
    AC1NWASH
    PEPCIDIN PEPCIDINE
    FAMOTIDINA [SPANISH]
    H2 BLOC
    FAMOTIDINUM [LATIN]
    DIBRIT 40
    PRESTWICK_212
    PEPCID AC GELCAPS
    PEPCIDIN RAPITAB
    NU-FAMOTIDINE
    FAMO
    GANOR
    FANOX
    FADYN
    FADIN
    DINUL
    WEIMOK
    PEPZAN
    PEPDIF
    FUDONE
    FADINE
    EVATIN
    DIPSIN
    YAMARIN
    WHITIDIN
    SIGAFAM
    PEPTIFAM
    PEPCIDINA
    PEPCIDAC
    FIBONEL
    FEROTINE
    FARMOTEX
    FANOBEL
    FAGASTINE
    DISPRONIL
    DSSTOX_GSID_23039
    DSSTOX_RID_76846
    76824-35-6
    DSSTOX_CID_3039
    CAS-76824-35-6
    PEPCID COMPLETE
    DB00927
    SEDANIUM-R
    CHEBI:4975
    NOVO-FAMOTIDINE
    APO-FAMOTIDINE
    ULFAM
    TAMIN
    MOSUL
    LOGOS
    HACIP
    FAMOX
    FAMOS
    CEPAL
    TOPCID
    TAIRAL
    PEPTAN
    PEPDUL
    MUCLOX
    FAMTAC
    DUOVEL
    BROLIN
    ULFINOL
    ULCOFAM
    ULCEPRAX
    ULCATIF
    ROGASTI
    RESTADIN
    QUAMTEL
    PURIFAM
    PEPTIDIN
    PEPCIDINE
    NULCERIN
    NEVOFAM
    NEOCIDINE
    MENSOMA
    INVIGAN
    INGASTRI
    N'-(AMINOSULFONYL)-3-[({2-[(DIAMINOMETHYLIDENE)AMINO]-1,3-THIAZOL-4-YL}METHYL)SULFANYL]PROPANIMIDAMIDE
    N -[AMINOSULFONYL]-3-[2-[DIAMINOMETHYLENEAMINO]-4-THIAZOLYL)METHYLTHIO]-PROPANAMIDINE
    3-{[(2-CARBAMIMIDAMIDO-1,3-THIAZOL-4-YL)METHYL]SULFANYL}-N-SULFAMOYLPROPANIMIDAMIDE
    N-SULFAMYL-3-[(2-GUANIDINO-4-THIAZOLYL)METHYLTHIO]PROPIONAMIDINE
    N-SULFAMOYL-3-[(2-GUANIDINOTHIAZOL-4-YL)METHYLTHIO]PROPIONAMIDINE
    3B3-004805
    95913-EP2303244A2
    89238-EP2305652A2
    89238-EP2305219A1
    89238-EP2275420A1
    AB1009281
    HE387276
    HE004824
    NCGC00255348-01
    NCGC00021202-03
    NCGC00018276-03
    LP00497
    CID5702160
    TOX21_110153_1
    DAP000341
    TOX21_301827
    TOX21_110153
    ZINC1530636
    PROPANIMIDAMIDE, N'-(AMINOSULFONYL)-3-(((2-((DIAMINOMETHYLENE)AMINO)-4-THIAZOLYL)METHYL)THIO)-
    PROPANIMIDAMIDE, 3-(((2-((AMINOIMINOMETHYL)AMINO)-4-THIAZOLYL)METHYL)THIO)-N-(AMINOSULFONYL)-
    N INVERTED EXCLAMATION MARKA-(AMINOSULFONYL)-3-([2-(DIAMINOMETHYLENEAMINO)-4-THIAZOLYL]METHYLTHIO)PROPANAMIDINE
    INCHI=1/C8H15N7O2S3/C9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/H4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
    (1Z)-N'-(AMINOSULFONYL)-3-[({2-[(DIAMINOMETHYLIDENE)AMINO]-1,3-THIAZOL-4-YL}METHYL)THIO]PROPANIMIDAMIDE
    (1Z)-3-[({2-[(DIAMINOMETHYLIDENE)AMINO]-1,3-THIAZOL-4-YL}METHYL)SULFANYL]-N'-SULFAMOYLPROPANIMIDAMIDE
    HMS3604N21
    HMS3393A07
    HMS3372J17
    PROPANIMIDAMIDE, 3-[[[2-[AMINOIMINOMETHYL)AMINO]-4-THIAZOYL]METHYL]THIO]-N-(AMINOSULFONYL)
    NINDS_000545
    3-[[2-(DIAMINOMETHYLIDENEAMINO)-1,3-THIAZOL-4-YL]METHYLSULFANYL]-N'-SULFAMOYLPRO
    3-(((2-((DIAMINOMETHYLENE)AMINO)-4-THIAZOLYL)METHYL)THIO)-N(SUP 2)-SULFAMOYLPROPIONAMIDINE
    3-(((2-((AMINOIMINOMETHYL)AMINO)-4-THIAZOLYL)METHYL)THIO)-N-(AMINOSULFONYL)PROPANIMIDAMIDE
    KBIO3_002354
    KBIO2_006858
    KBIO2_004290
    KBIO2_001722
    KBIO1_000545
    GTPL7074
    GASTROPEN
    N-SULFAMOYL-3-((2-GUANIDINOTHIAZOL-4-YL)METHYLTHIO)PROPIONAMIDE
    SPBIO_002027
    SPBIO_001251
    DIVK1C_000545
    KBIOSS_001722
    KBIOGR_000676
    FAMOTIDINE PRESERVATIVE FREE IN PLASTIC CONTAINER
    SPECTRUM4_000408
    SPECTRUM3_001427
    SPECTRUM2_001036
    PRESTWICK1_000104
    PRESTWICK0_000104
    PEPCID PRESERVATIVE FREE IN PLASTIC CONTAINER
    L 643341
    AC1L1FOE
    L013386
    L003830
    SPECTRUM_001242
    F 6889
    F0530
    EU-0100497
    TL8005267
    LS-121117
    YM-11170
    YM 11170
    SMR000058961
    SAM001247033
    CPD000058961
    AC-11713
    NCGC00093899-03
    NCGC00093899-02
    NCGC00093899-01
    NCGC00018276-02
    NCGC00018276-01
    NCGC00015446-06
    NCGC00015446-05
    NCGC00015446-03
    NCGC00015446-02
    NCGC00015446-01
    (1-AMINO-3-(((2-((DIAMINOMETHYLENE)AMINO)-4-THIAZOLYL)METHYL)THIO)PROPYLIDENE)SULFAMIDE
    YM-1170
    STK527689
    PDSP2_000396
    PDSP1_000398
    MK 208
    FAMOTIDINE PRESERVATIVE FREE
    FAMOTIDINE [USAN:BAN:INN:JAN]
    PEPCIDREG
    HMS2089I12
    HMS2051A07
    HMS1568E10
    GASTERREG
    XUFQPHANEAPEMJ-UHFFFAOYSA-N
    MOLPORT-003-941-395
    MOLPORT-002-557-620
    XUFQPHANEAPEMJ-UHFFFAOYSA-
    HSDB 3572
    BPBIO1_000098
    AC1Q50E1
    AC1Q50E0
    PEPCID PRESERVATIVE FREE
    F6889_SIGMA
    BIO-0739
    BIDD:GT0759
    MLS001423994
    HUBERDINA
    GASTROFAM
    GASTRION
    GASTRIDIN
    GASTRIDAN
    FANOSIN
    FAMULCER
    FAMOXAL
    FAMOWAL
    FAMOVANE
    FAMOTIN
    FAMOTAL
    FAMOPSIN
    FAMONIT
    FAMOGARD
    FAMODINE
    FAMODIN
    FAMODIL
    FAMODAR
    DURATER
    DISPROMIL
    DIGERVIN
    CUANTIN
    BLOCACID
    BESTIDINE
    SUPERTIDINE
    GASTROSIDIN
    GASTRODOMINA
    FAMOTIDINUM
    FAMOTIDINA
    APOGASTINE
    MYLANTA AR
    MOTIAX
    GASTRO
    CRONOL
    VAGOSTAL
    ULGARINE
    ULFAMID
    ULFAGEL
    TIPODEX
    RUBACINA
    RENAPEPSA
    QUAMATEL
    PEPFAMIN
    PEPDINE
    PEPCIDIN
    PANALBA
    NULCERAN
    NOTIDIN
    FAMOTEP
    FAMOSAN
    FAMOCID
    CONFOBOS
    ANTODINE
    3325
    AMFAMOX
    MIDEFAM
    LECEDIL
    UNII-5QZO15J2Z8
    N'-(AMINOSULFONYL)-3-([2-(DIAMINOMETHYLENEAMINO)-4-THIAZOLYL]METHYLTHIO)PROPANAMIDINE
    HS-0054
    C8H15N7O2S3
    3-((2-(DIAMINOMETHYLENEAMINO)THIAZOL-4-YL)METHYLTHIO)-N-SULFAMOYLPROPANIMIDAMIDE
    3-[(2-GUANIDINOTHIAZOL-4-YL)METHYLSULFANYL]-N-SULFAMOYL-PROPANAMIDINE
    D00318
    ST51001070
    K328
    BC203224
    NCGC00188952-01
    NCGC00015446-04
    NC00017
    MCULE-1972636463
    CS-2445
    CCG-221801
    CCG-220104
    CCG-100767
    AB03031
    AKOS015994617
    AKOS005460541
    KM1798
    DNC000677
    DCL000399
    HY-B0377
    HMS3261D15
    HMS2231I22
    HMS2095E10
    MOLPORT-006-069-255
    HMDB01919
    CID_5702160
    BDBM22891
    CHEMBL1318051
    FAMOTIDINE (JP16/USP/INN)
    5QZO15J2Z8
    SCHEMBL974
    SCHEMBL972
    PEPCID (TN)
    FLUXID (TN)
    GASTER
    5702160
    3-[[[2-[(AMINOIMINOMETHYL)AMINO]-4-THIAZOLYL]METHYL]THIO]-N-(AMINOSULFONYL)-PROPANIMIDAMIDE
    3-[({2-[(DIAMINOMETHYLENE)AMINO]-1,3-THIAZOL-4-YL}METHYL)SULFANYL]-N'-SULFAMOYLPROPANIMIDAMIDE
    1-AMINO-3-[[[[2-[(DIAMINOMETHYLENE)AMINO]-4-THIAZOLYL]METHYL]THIO]PROPYLIDENE]SULFAMIDE
    (Z)-3-((2-(DIAMINOMETHYLENEAMINO)THIAZOL-4-YL)METHYLTHIO)-N'-SULFAMOYLPROPANIMIDAMIDE
    (1Z)-2-AMINO-4-{[2-(2,2-DIAMINO-1-AZAVINYL)(1,3-THIAZOL-4-YL)]METHYLTHIO}-1-AZ ABUT-1-ENESULFONAMIDE
    N'-[AMINOSULFONYL]-3-[2-[DIAMINOMETHYLENEAMINO]-4-THIAZOLYL)METHYLTHIO]-PROPANAMIDINE
    3-((2-(DIAMINOMETHYLENEAMINO)THIAZOL-5-YL)METHYLTHIO)-N'-SULFAMOYLPROPANIMIDAMIDE
    Up and Up Famotidine Complete
    Up and Up Famotidine
    Up and Up Dual Action Acid Controller Complete
    Up and Up Acid Reducer Original Strength
    Up and Up Acid Controller Complete Dual Action
    Ulcidine
    Topcare Dual Action Complete
    Topcare Complete Acid Reducer Plus Antacid
    Topcare Complete
    Topcare Acid Reducer
    Teva-famotidine
    Sunmark Dual Action Complete
    Sunmark Complete
    Sunmark Acid Reducer Maximum Strength
    Sunmark Acid Reducer
    Sound Body Acid Reducer
    Smart Sense Famotidine
    Smart Sense Dual Action Complete
    Smart Sense Complete
    Smart Sense Acid Reducer Maximum Strength
    Smart Sense Acid Reducer
    Simply Right Famotidine Complete
    Simply Right Famotidine
    Signature Care Acid Reducer Complete
    Signature Care Acid Controller Maximum Strength
    Signature Care Acid Controller Complete
    Signature Care Acid Controller
    Shoprite Dual Action Complete
    Shoprite Complete
    Shoprite Acid Reducer
    Rx Act Heartburn Prevention Maximum Strength
    Riva-famotidine 40 mg
    Riva-famotidine 20 mg
    Rhoxal-famotidine
    Ratio-famotidine 40mg
    Ratio-famotidine 20mg
    Premier Value Famotidine
    Preferred Plus Complete
    Peptic Guard
    Pepcid Tab 40mg
    Pepcid Tab 20mg
    Pepcid I.V. 10mg/ml
    Pepcid Ac Original Strength
    Pepcid Ac Maximum Strength
    Pepcid Ac (chewable Tab) - 10mg
    Penta-famotidine
    Nu-famotidine Tab 40mg
    Nu-famotidine Tab 20mg
    Ntp-famotidine
    Mylan-famotidine
    Members Mark Famotidine
    Maximum Strength Pepcid Ac
    Maximum Strength Acid Reducer
    Maximum Strength
    Major Heartburn Relief Maximum Strength
    Maalox H2 Acid Controller
    Leader Acid Reducer Original Strength
    Leader Acid Reducer Maximum Strength
    Leader Acid Reducer Complete
    Kirkland Signature Acid Controller
    Humana Pharmacy Acid Reducer
    Heartburn Relief Original Strength
    Heartburn Relief
    Heartburn Prevention Original Strength
    Heartburn Prevention Acid Reducer
    Heartburn Prevention
    Healthy Accents Famotidine Maximum Strength
    Healthy Accents Famotidine Calcium Carbonate Magnesium Hydroxide
    Healthy Accents Famotidine
    Health Mart Famotidine
    Health Mart Dual Action Complete
    Health Mart Complete
    Harris Teeter Acid Reducer
    Good Sense Dual Action Complete
    Good Sense Complete
    Good Sense Acid Reducer
    Good Neighbor Pharmacy Dual Action Complete
    Good Neighbor Pharmacy Complete
    Good Neighbor Pharmacy Acid Reducer Maximum Strength
    Good Neighbor Pharmacy Acid Reducer
    Famotidine-40
    Famotidine-20
    Famotidine Tablets
    Famotidine Original Strength
    Famotidine Omega -(without Preservative)
    Famotidine Omega -(with Preservative,benzyl Alcohol)
    Famotidine Injection
    Famotidine IV Injection
    Famotidine 10mg
    Famotidine - Acid Controller
    Family Wellness Acid Reducer
    Family Wellness Acid Controller Complete
    Equate Famotidine
    Equate Acid Reducer Complete
    Equate Acid Controller Original Strength
    Equaline Heartburn Prevention
    Equaline Complete Dual Action
    Duo Fusion
    Duexis
    Dual Action Complete
    Dual Action
    Dg Health Heartburn Prevention Original Strength
    Dg Health Heartburn Prevention
    Dg Health Dual Action Complete
    Complete Dual Action
    Careone Acid Relief
    Careone Acid Reducer Complete
    Careone Acid Reducer
    Care One Acid Reducer and Antacid Dual Action
    Care One Acid Reducer Plus Antacid Dual Action
    Care One Acid Reducer Original Strength
    Calmicid Ac Acid Reducer
    Berkley and Jensen Famotidine
    Berkley and Jensen Acid Controller Complete
    Berkley and Jensen Acid Controller
    Bci Famotidine
    Apo-famotidine Tab 40mg USP
    Apo-famotidine Tab 20mg USP
    Apo-famotidine Injectable
    Act
    Acid Reducer Plus Antacid
    Acid Reducer Original Strength
    Acid Reducer Maximum Strength
    Acid Reducer Complete
    Acid Reducer
    Acid Controller Original Strength
    Acid Controller Maximum Strength
    Acid Controller Complete Dual Action
    Acid Controller Complete
    Acid Controller
    Acid Control Original Strength
    Acid Control
    7 Select Acid Controller
    178103653
    7074
    191368
    3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)-N1-SULFAMOYLPROPIONAMIDE
    49698346
    GSK1004723
    N-SULFOMOYL-3-(2-GUANIDINO-2H-1LAMBDA*4*-THIAZOL-4-YLMETHYLSULFANYL)-PROPIONAMIDINE
    3-(2-GUANIDINO-THIAZOL-4-YLMETHYLSULFANYL)-N-SULFONYLAMINO-PROPIONAMIDINE
    BRD-K00673382-001-05-6
    108885-67-2 (HCL)
    FAMOTIDINE PRESERVATIVE FREE (PHARMACY BULK)
    NCGC00094885-03
    NCGC00094885-02
    NCGC00094885-01
    IDI1_000545
    NSC-757810
    FAMOTIDINE [USAN:USP:INN:BAN:JAN]
    NSC757810
    CCG-40241
    BDBM50036754
    PHARMAKON1600-01501003
    HMS2092O18
    HMS1921B05
    HMS501L07
    SPECTRUM1501003
    BSPBIO_003134
    SPECTRUM5_001357
    AC1NS4DZ
    MAJOR HEARTBURN RELIEF
    N''-(AMINOSULFONYL)-3-(((2-((DIAMINOMETHYLENE)AMINO)-4-THIAZOLYL)METHYL)THIO)PROPANIMIDAMIDE
    (1Z)-N''-(AMINOSULFONYL)-3-[({2-[(DIAMINOMETHYLENE)AMINO]-1,3-THIAZOL-4-YL}METHYL)THIO]PROPANIMIDAMIDE (FAMOTIDINE)
    (1Z)-N''-(AMINOSULFONYL)-3-[({2-[(DIAMINOMETHYLENE)AMINO]-1,3-THIAZOL-4-YL}METHYL)THIO]PROPANIMIDAMIDE
    5353622
    PEPCID AC (GELTAB)

    Drug Info:

    Year of Approval 1986
    Drug Class gi anti-ulcer agents, antihistamines
    Drug Categories thiazoles
    Drug Categories therapeutic uses
    Drug Categories sulfur compounds
    Drug Categories qtc-prolonging agents (indeterminate risk and risk modifying)
    Drug Categories physiological effects of drugs
    Drug Categories pharmacologic actions
    Drug Categories organic chemicals
    Drug Categories neurotransmitter agents
    Drug Categories molecular mechanisms of pharmacological action
    Drug Categories inorganic chemicals
    Drug Categories histamine h2 antagonists
    Drug Categories histamine antagonists
    Drug Categories histamine agents
    Drug Categories heterocyclic compounds, 1-ring
    Drug Categories heterocyclic compounds
    Drug Categories h2-receptor antagonists
    Drug Categories h2 antagonists
    Drug Categories gastrointestinal agents
    Drug Categories drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)
    Drug Categories drugs for acid related disorders
    Drug Categories cytochrome p-450 cyp2c19 substrates
    Drug Categories chemical actions and uses
    Drug Categories azoles
    Drug Categories anti-ulcer agents
    Drug Categories alimentary tract and metabolism
    Drug Groups approved
    Drug Type small molecule
    Drug Indications for treatment of gastric ulcer and gastroesophageal reflux
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications acid reducer
    (7 More Sources)

    Publications:

    Lesclous et al., 2006, Histamine mediates osteoclastic resorption only during the acute phase of bone loss in ovariectomized rats., Exp. Physiol.
    Weydert et al., 2003, Systematic review of treatments for recurrent abdominal pain., Pediatrics
    Kesiova et al., Effects of diphenhydramine and famotidine on lipid peroxidation and activities of antioxidant enzymes in different rat tissues., Pharmacol Rep
    Takahashi et al., 2006, Cimetidine induces interleukin-18 production through H2-agonist activity in monocytes., Mol. Pharmacol.
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Leurs et al., 1991, Effects of histamine H1-, H2- and H3-receptor selective drugs on the mechanical activity of guinea-pig small and large intestine., Br. J. Pharmacol.
    Ojiako et al., 2008, Famotidine versus pantoprazole for preventing bleeding in the upper gastrointestinal tract of critically ill patients receiving mechanical ventilation., Am. J. Crit. Care
    Miyata et al., 1991, Studies on the mechanism for the gastric mucosal protection by famotidine in rats., Jpn. J. Pharmacol.
    Inan et al., 2009, Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats., Clinics (Sao Paulo)
    Amagase et al., 2003, On the mechanisms underlying histamine induction of gastric mucosal lesions in rats with partial gastric vascular occlusion., J. Pharmacol. Sci.
    Fukuda et al., 2007, Cimetidine induces apoptosis of human salivary gland tumor cells., Oncol. Rep.
    Esaki et al., 2002, Effects of omeprazole and famotidine on fibroblast growth factor-2 during artificial gastric ulcer healing in humans., Eur J Gastroenterol Hepatol
    Itoh et al., 2002, Effects of histamine H(2)-receptor antagonists on human plasma levels of calcitonin gene-related peptide, substance P and vasoactive intestinal peptide., J. Pharm. Pharmacol.