• CRISABOROLE CHEMBL484785 FDA Approved

    Alternate Names:

    Crisaborole
    AN-2728
    1187189-21-4
    4-((1-HYDROXY-1,3-DIHYDROBENZO-[C][1,2]OXABOROL-5-YL)OXY)BENZONITRILE
    4-(1-HYDROXY-1,3-DIHYDROBENZO[C][1,2]OXABOROL-5-YLOXY)BENZONITRILE
    4-((1-HYDROXY-1,3-DIHYDROBENZO(C)(1,2)OXABOROL-6-YL)OXY)BENZONITRILE
    4-[(1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROL-5-YL)OXY]BENZONITRILE
    4-[(1-HYDROXY-3H-2,1-BENZOXABOROL-5-YL)OXY]BENZONITRILE
    5-(4-CYANOPHENOXY)-1-HYDROXY-2,1-BENZOXABOROLE
    W-5676
    ST24042710
    TC-154281
    DB-078771
    KB-40872
    HY-10978
    HE268247
    HE053309
    BC245091
    AK102641
    NCGC00345792-01
    CS-1057
    ZINC169748244
    AKOS016005425
    BDBM50277665
    ANW-65536
    ABP001114
    5098AC
    USZAGAREISWJDP-UHFFFAOYSA-N
    MOLPORT-023-332-548
    CTK8C0958
    C14H10BNO3
    SCHEMBL595261
    CRISABOROLE [INN]
    1073669-75-6
    BENZONITRILE, 4-[(1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROL-5-YL)OXY]-
    BENZONITRILE, 4-((1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROL-5-YL)OXY)-
    5-(4-CYANOPHENOXY)-2,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE
    Q2R47HGR7P
    AN 2728
    UNII-Q2R47HGR7P
    AN2728
    4-((1-HYDROXY-1,3-DIHYDROBENZO[C][1,2]OXABOROL-5-YL)OXY)BENZONITRILE
    44591583
    906673-24-3
    Eucrisa
    DB05219
    315661236
    9151
    5-(4-AMINOMETHYL-PHENOXY)-3H-BENZO[C][1,2]OXABOROL-1-OL
    USQKBFNKMYRGGS-UHFFFAOYSA-N
    57968923
    SCHEMBL2529581

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications antiinflammatory agent, antipsoriatic
    Drug Categories polycyclic compounds
    Drug Categories organic chemicals
    Drug Categories inorganic chemicals
    Drug Categories hydrocarbons, cyclic
    Drug Categories hydrocarbons
    Drug Categories heterocyclic compounds, bridged-ring
    Drug Categories heterocyclic compounds, 2-ring
    Drug Categories heterocyclic compounds
    Drug Categories cytochrome p-450 cyp2c9 inhibitors (moderate)
    Drug Categories cytochrome p-450 cyp2c9 inhibitors
    Drug Categories cytochrome p-450 cyp2c8 inhibitors (moderate)
    Drug Categories cytochrome p-450 cyp2c8 inhibitors
    Drug Categories cytochrome p-450 cyp2b6 inhibitors (weak)
    Drug Categories cytochrome p-450 cyp2b6 inhibitors
    Drug Categories cytochrome p-450 cyp1a2 inhibitors (weak)
    Drug Categories cytochrome p-450 cyp1a2 inhibitors
    Drug Categories bridged compounds
    Drug Categories bicyclo compounds
    Drug Groups approved
    Drug Type small molecule
    (2 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Trial Name AN-2728
    Novel drug target Established target
    Mechanism of Interaction Phosphodiesterase 4 inhibitor

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 4 inhibitor
    Direct Interaction yes
    Specific Action of the Ligand Inhibition

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 4 inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 4 inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

    • Version: 5.0.8

    Alternate Names:
    CRISABOROLE DrugBank Drug Name
    906673-24-3 CAS Number
    Eucrisa Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Categories bicyclo compounds

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antiinflammatory agent, antipsoriatic
    Drug Class Small molecule
    FDA Approval not approved

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    906673-24-3 pubchem_primary_name
    44591583 PubChem CID
    4-((1-HYDROXY-1,3-DIHYDROBENZO[C][1,2]OXABOROL-5-YL)OXY)BENZONITRILE Drug Synonym

    Drug Info:

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    SCHEMBL2529581 pubchem_primary_name
    57968923 PubChem CID
    USQKBFNKMYRGGS-UHFFFAOYSA-N Drug Synonym

    Drug Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    CRISABOROLE GuideToPharmacology Ligand Name
    315661236 PubChem Drug SID

    Drug Info:

    Publications:

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications: