Zaponex |
Clozapine |
Clozaril |
Fazaclo |
HF-1854 |
Fazaclo Odt |
C28936 |
Zopin |
Ziproc |
Zapine |
Zapenia |
Zapen |
Versacloz |
Uspen |
Tanyl |
Syzopin |
Syclop |
Sizopril |
Sizopin |
Sequax |
Sensipin |
Sandoz Clozapine |
Refraxol |
Refract |
PMS-clozapine |
Mezapin |
Luften |
Lozapin |
Lodux |
Leponex |
Lapenax |
Lanolept |
Gen-clozapine |
Clorazem |
Clopsine |
Clopine |
Clopin |
Clonex |
Cloment |
Azaleptine |
Auro-clozapine |
Aa-clozapine |
5786-21-0 |
Clozapina |
DB00363 |
22869 |
2716 |
46506474 |
ASALEPTIN |
57664-345-88 |
C06924 |
D00283 |
7847349 |
CN1CCN(CC1)C2=NC3CC(CCC3NC4C2CCCC4)CL |
2818 |
3766 |
IPROX |
2240669 |
PA449061 |
CLOZAPIN |
DAP000029 |
LEPOTEX |
BC204168 |
AN-16004 |
NCGC00188978-01 |
NCGC00022902-12 |
NCGC00015254-20 |
NCGC00015254-18 |
NCGC00015254-16 |
NCGC00015254-15 |
NCGC00015254-14 |
NCGC00015254-13 |
NCGC00015254-11 |
NCGC00015254-10 |
NCGC00015254-09 |
NCGC00015254-08 |
NCGC00015254-06 |
NCGC00015254-05 |
NCGC00015254-04 |
NSC-757429 |
NC00667 |
MCULE-3665900006 |
LP00276 |
CS-0644 |
CLOZAPINE-SUPPLIED BY SELLECK CHEMICALS |
TOX21_110113_1 |
ZINC19796155 |
NSC757429 |
CCG-39881 |
CC0176 |
BDBM50001884 |
ANW-42470 |
TOX21_110113 |
ZINC3872123 |
PHARMAKON1600-01500685 |
HMS3402P12 |
HMS3371H05 |
HMS3266A10 |
HMS3260H14 |
HMS3259J17 |
HMS2235E19 |
HMS2096E21 |
CLOZAPINE [USAN:USP:INN:BAN] |
AOB5635 |
QZUDBNBUXVUHMW-UHFFFAOYSA- |
CTK6I2968 |
BDBM22869 |
SCHEMBL33323 |
REGID_FOR_CID_2818 |
INCHI=1/C18H19CLN4/C1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/H2-7,12,20H,8-11H2,1H3 |
6-CHLORO-10-(4-METHYLPIPERAZIN-1-YL)-2,9-DIAZATRICYCLO[9.4.0.03,8]PENTADECA-1(11),3,5,7,9,12,14-HEPTAENE |
6-CHLORO-10-(4-METHYLPIPERAZIN-1-YL)-2,9-DIAZATRICYCLO[9.4.0.0^{3,8}]PENTADECA-1,3(8),4,6,10,12,14-HEPTAENE |
6-CHLORO-10-(4-METHYLPIPERAZIN-1-YL)-2,9-DIAZATRICYCLO[9.4.0.0?,?]PENTADECA-1,3(8),4,6,10,12,14-HEPTAENE |
6-CHLORO-10-(4-METHYLPIPERAZIN-1-YL)-2,9-DIAZATRICYCLO[9.4.0.0(3),?]PENTADECA-1,3(8),4,6,10,12,14-HEPTAENE |
CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE |
8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE(CLOPAZINE) |
8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE(CIOZAPINE) |
8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE( CLOZEPINE ) |
8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE (CLOZAPINE) |
3-HYDROXY-2-PHENYL-PROPIONIC ACID 8-METHYL-8-AZA-BICYCLO[3.2.1]OCT-3-YL ESTER |
8-CHLORO-11-(4-METHYLPIPERAZIN-1-YL)-10H-DIBENZO[B,E][1,4]DIAZEPINE |
8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-10H-DIBENZO[B,E][1,4]DIAZEPINE |
3-CHLORO-6-(4-METHYLPIPERAZIN-1-YL)-11H-BENZO[B][1,4]BENZODIAZEPINE |
8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE |
I06-0047 |
BRD-K37289225-001-09-1 |
L013417 |
L000195 |
DSSTOX_GSID_22855 |
DSSTOX_RID_76759 |
C 6305 |
DSSTOX_CID_2855 |
5H-DIBENZO[B,E][1,4]DIAZEPINE, 8-CHLORO-11-(4-METHYL-1-PIPERAZINYL)- |
3-CHLORO-6-(4-METHYLPIPERAZIN-1-YL)-5H-BENZO[B][1,4]BENZODIAZEPINE |
LX 100-129 |
FT-0082373 |
EU-0100276 |
SMR000058365 |
SAM002548976 |
AB00052158-14 |
AB00052158-13 |
W-2845 |
EN300-52510 |
FT-0600382 |
D-107 |
C2547 |
TC-063560 |
AB1009321 |
AB0013069 |
SAM002589962 |
PL001733 |
HY-14539 |
H482 |
LS-60881 |
CPD000058365 |
NCGC00022902-13 |
NCGC00022902-11 |
NCGC00022902-10 |
NCGC00022902-09 |
NCGC00022902-08 |
NCGC00022902-07 |
NCGC00022902-06 |
NCGC00022902-05 |
NCGC00022902-04 |
NCGC00022902-02 |
NCGC00015254-17 |
NCGC00015254-12 |
NCGC00015254-07 |
NCGC00015254-03 |
NCGC00015254-02 |
NCGC00015254-01 |
AKOS005064444 |
AR-1I2412 |
AC-280 |
5H-DIBENZO(B,E)(1,4)DIAZEPINE, 8-CHLORO-11-(4-METHYL-1-PIPERAZINYL)- |
HMS2092I16 |
HMS2089L13 |
HMS1989P12 |
HMS1921C16 |
HMS1791P12 |
HMS1569E21 |
HMS1361P12 |
BIO2_000790 |
BIO2_000310 |
BIO1_001414 |
BIO1_000925 |
BIO1_000436 |
QZUDBNBUXVUHMW-UHFFFAOYSA-N |
MOLPORT-001-728-041 |
NINDS_000343 |
LEX-123 |
KBIO3_002979 |
KBIO3_000620 |
KBIO3_000619 |
KBIO2_005735 |
KBIO2_005446 |
KBIO2_003167 |
KBIO2_002878 |
KBIO2_000599 |
KBIO2_000310 |
KBIO1_000343 |
HMS501B05 |
MLS001077282 |
MLS000028472 |
SPECTRUM1500685 |
SPBIO_002340 |
SPBIO_000798 |
CAS-5786-21-0 |
DIVK1C_000343 |
C6305_SIGMA |
CLOZAPINE [USAN:INN:BAN] |
KBIOSS_000599 |
KBIOSS_000310 |
KBIOGR_001336 |
KBIOGR_000310 |
CLOZAPINE (JAN/USP/INN) |
BRN 0764984 |
KS-1166 |
HF1854 |
LOPAC-C-6305 |
EINECS 227-313-7 |
SPECTRUM4_000898 |
SPECTRUM3_001828 |
SPECTRUM2_000919 |
PRESTWICK1_000350 |
PRESTWICK0_000350 |
AC1Q3ZWP |
AC1Q3OPZ |
AC1L1EJE |
TOCRIS-0444 |
SPECTRUM_000139 |
8-CHLORO-11-(4-METHYLPIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE |
HSDB 6478 |
3-CHLORO-6-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE |
8-CHLORO-11-(4-METHYLPIPERAZINO)-5H-DIBENZO[B,E][1,4]DIAZEPINE |
3B3-036001 |
W-105432 |
T7100235 |
D003024 |
SCHEMBL8397 |
GTPL38 |
J60AR2IKIC |
CLOZAPINE, CLOZARIL, AZALEPTIN, LEPONEX, FAZACLO, FROIDIR, DENZAPINE, ZAPONEX |
CID2818 |
KLOZAPOL |
AZALEPTIN |
CLORAZILREG |
S2459_SELLECK |
CHEBI:3766 |
CCRIS 9171 |
HF 1854 |
PRESTWICK_693 |
C18H19CLN4 |
CLOZARIL (TN) |
CLOZAPINA [INN-SPANISH] |
UNII-J60AR2IKIC |
CLOZAPINUM [INN-LATIN] |
W-801 |
CLOZAPINE(TAUTOMER) |
CLOZAPINUM |
CLORAZIL |
135650115 |
38 |
178100616 |
[125I]αCGRP (HUMAN) |
Drug Categories | tranquilizing agents |
Drug Categories | therapeutic uses |
Drug Categories | serotonin antagonists |
Drug Categories | serotonin agents |
Drug Categories | psychotropic drugs |
Drug Categories | psycholeptics |
Drug Categories | physiological effects of drugs |
Drug Categories | pharmacologic actions |
Drug Categories | p-glycoprotein/abcb1 substrates |
Drug Categories | neurotransmitter agents |
Drug Categories | nervous system |
Drug Categories | molecular mechanisms of pharmacological action |
Drug Categories | moderate risk qtc-prolonging agents |
Drug Categories | hypotensive agents |
Drug Categories | hyperglycemia-associated agents |
Drug Categories | heterocyclic compounds, 3-ring |
Drug Categories | heterocyclic compounds |
Drug Categories | gaba antagonists |
Drug Categories | gaba agents |
Drug Categories | dibenzazepines |
Drug Categories | diazepines, oxazepines, thiazepines and oxepines |
Drug Categories | cytochrome p-450 cyp3a4 substrates |
Drug Categories | cytochrome p-450 cyp3a inhibitors |
Drug Categories | cytochrome p-450 cyp3a inducers |
Drug Categories | cytochrome p-450 cyp2e1 inhibitors |
Drug Categories | cytochrome p-450 cyp2d6 substrates |
Drug Categories | cytochrome p-450 cyp2d6 inhibitors (moderate) |
Drug Categories | cytochrome p-450 cyp2d6 inhibitors |
Drug Categories | cytochrome p-450 cyp2c9 substrates |
Drug Categories | cytochrome p-450 cyp2c9 inhibitors |
Drug Categories | cytochrome p-450 cyp2c8 substrates |
Drug Categories | cytochrome p-450 cyp2c19 substrates |
Drug Categories | cytochrome p-450 cyp2c19 inhibitors |
Drug Categories | cytochrome p-450 cyp2a6 substrates |
Drug Categories | cytochrome p-450 cyp1a2 substrates |
Drug Categories | cytochrome p-450 cyp1a2 inhibitors (weak) |
Drug Categories | cytochrome p-450 cyp1a2 inhibitors |
Drug Categories | chemical actions and uses |
Drug Categories | central nervous system depressants |
Drug Categories | central nervous system agents |
Drug Categories | antipsychotic agents (second generation [atypical]) |
Drug Categories | antipsychotic agents |
Drug Categories | antiemetics antagonists |
Drug Categories | alpha1 antagonists |
Drug Groups | approved |
Drug Type | small molecule |
Drug Class | antipsychotic agents |
Year of Approval | 1989 |
FDA Approval | 1989 |
Drug Class | small molecule |
Drug Indications | Antipsychotic Agents |
ATC | n05ah(diazepines |
Drug Type | drug/small molecule |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Trial Name | - |
antagonist |
Trial Name | - |
Novel drug target | Established target |
Specific Action of the Ligand | Inverse agonist |
agonist |
Specific Action of the Ligand | Full agonist |
Endogenous Drug? | False |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
agonist |
Specific Action of the Ligand | Full agonist |
Endogenous Drug? | False |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
antagonist |
Specific Action of the Ligand | Inverse agonist |
Endogenous Drug? | False |
agonist |
Specific Action of the Ligand | Agonist |
Endogenous Drug? | False |
Direct Interaction? | False |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Trial Name | - |
antagonist |
Mechanism of Interaction | Serotonin 2a (5-HT2a) receptor antagonist |
Direct Interaction | yes |
Trial Name | - |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Direct Interaction? | True |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
agonist |
antagonist |
Trial Name | - |
Novel drug target | Established target |
Specific Action of the Ligand | Full agonist |
agonist |
antagonist |
Specific Action of the Ligand | Full agonist |
Endogenous Drug? | False |
agonist |
antagonist |
Endogenous Drug? | False |
Specific Action of the Ligand | Full agonist |
agonist |
antagonist |
Specific Action of the Ligand | Full agonist |
Endogenous Drug? | False |
antagonist |
antagonist |
Specific Action of the Ligand | Inverse agonist |
Endogenous Drug? | False |
antagonist |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Trial Name | - |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Trial Name | - |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
antagonist |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
antagonist |
antagonist |
antagonist |
antagonist |
allosteric modulator |
Specific Action of the Ligand | Positive |
Endogenous Drug? | False |
antagonist |
antagonist |
antagonist |
antagonist |
unknown |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
n/a |
CLOZAPINE | DrugBank Drug Name |
Clozapina | Drug Synonym |
Clozapine | Drug Synonym |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | alpha1 antagonists |
CLOZAPINE | Primary Drug Name |
Year of Approval | 1989 |
Drug Class | antipsychotic agents |
LEPONEX | Drug Trade Name |
LEPOTEX | Drug Trade Name |
FAZACLO ODT | Drug Trade Name |
Drug Type | drug/small molecule |
ATC | n05ah(diazepines |
Drug Indications | Antipsychotic Agents |
Drug Class | small molecule |
FDA Approval | 1989 |
C28936 | NCI drug code |
[125I]αCGRP (HUMAN) | GuideToPharmacology Ligand Name |
178100616 | PubChem Drug SID |
HMS1921C16 | Drug Synonym |
SPECTRUM_000139 | Drug Synonym |
KBIOGR_000310 | Drug Synonym |
CLOZAPINE | pubchem_primary_name |
2818 | PubChem CID |
LEPONEX | Drug Synonym |
CLOZAPINE | GuideToPharmacology Ligand Name |
135650115 | PubChem Drug SID |