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CLOZAPINE CHEMBL42 FDA Approved
Alternate Names:
Zaponex Clozapine Clozaril Fazaclo HF-1854 Fazaclo Odt C28936 Zopin Ziproc Zapine Zapenia Zapen Versacloz Uspen Tanyl Syzopin Syclop Sizopril Sizopin Sequax Sensipin Sandoz Clozapine Refraxol Refract PMS-clozapine Mezapin Luften Lozapin Lodux Leponex Lapenax Lanolept Gen-clozapine Clorazem Clopsine Clopine Clopin Clonex Cloment Azaleptine Auro-clozapine Aa-clozapine 5786-21-0 Clozapina DB00363 22869 2716 46506474 ASALEPTIN 57664-345-88 C06924 D00283 7847349 CN1CCN(CC1)C2=NC3CC(CCC3NC4C2CCCC4)CL 2818 3766 IPROX 2240669 PA449061 CLOZAPIN DAP000029 LEPOTEX BC204168 AN-16004 NCGC00188978-01 NCGC00022902-12 NCGC00015254-20 NCGC00015254-18 NCGC00015254-16 NCGC00015254-15 NCGC00015254-14 NCGC00015254-13 NCGC00015254-11 NCGC00015254-10 NCGC00015254-09 NCGC00015254-08 NCGC00015254-06 NCGC00015254-05 NCGC00015254-04 NSC-757429 NC00667 MCULE-3665900006 LP00276 CS-0644 CLOZAPINE-SUPPLIED BY SELLECK CHEMICALS TOX21_110113_1 ZINC19796155 NSC757429 CCG-39881 CC0176 BDBM50001884 ANW-42470 TOX21_110113 ZINC3872123 PHARMAKON1600-01500685 HMS3402P12 HMS3371H05 HMS3266A10 HMS3260H14 HMS3259J17 HMS2235E19 HMS2096E21 CLOZAPINE [USAN:USP:INN:BAN] AOB5635 QZUDBNBUXVUHMW-UHFFFAOYSA- CTK6I2968 BDBM22869 SCHEMBL33323 REGID_FOR_CID_2818 INCHI=1/C18H19CLN4/C1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/H2-7,12,20H,8-11H2,1H3 6-CHLORO-10-(4-METHYLPIPERAZIN-1-YL)-2,9-DIAZATRICYCLO[9.4.0.03,8]PENTADECA-1(11),3,5,7,9,12,14-HEPTAENE 6-CHLORO-10-(4-METHYLPIPERAZIN-1-YL)-2,9-DIAZATRICYCLO[9.4.0.0^{3,8}]PENTADECA-1,3(8),4,6,10,12,14-HEPTAENE 6-CHLORO-10-(4-METHYLPIPERAZIN-1-YL)-2,9-DIAZATRICYCLO[9.4.0.0?,?]PENTADECA-1,3(8),4,6,10,12,14-HEPTAENE 6-CHLORO-10-(4-METHYLPIPERAZIN-1-YL)-2,9-DIAZATRICYCLO[9.4.0.0(3),?]PENTADECA-1,3(8),4,6,10,12,14-HEPTAENE CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE(CLOPAZINE) 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE(CIOZAPINE) 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE( CLOZEPINE ) 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE (CLOZAPINE) 3-HYDROXY-2-PHENYL-PROPIONIC ACID 8-METHYL-8-AZA-BICYCLO[3.2.1]OCT-3-YL ESTER 8-CHLORO-11-(4-METHYLPIPERAZIN-1-YL)-10H-DIBENZO[B,E][1,4]DIAZEPINE 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-10H-DIBENZO[B,E][1,4]DIAZEPINE 3-CHLORO-6-(4-METHYLPIPERAZIN-1-YL)-11H-BENZO[B][1,4]BENZODIAZEPINE 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE I06-0047 BRD-K37289225-001-09-1 L013417 L000195 DSSTOX_GSID_22855 DSSTOX_RID_76759 C 6305 DSSTOX_CID_2855 5H-DIBENZO[B,E][1,4]DIAZEPINE, 8-CHLORO-11-(4-METHYL-1-PIPERAZINYL)- 3-CHLORO-6-(4-METHYLPIPERAZIN-1-YL)-5H-BENZO[B][1,4]BENZODIAZEPINE LX 100-129 FT-0082373 EU-0100276 SMR000058365 SAM002548976 AB00052158-14 AB00052158-13 W-2845 EN300-52510 FT-0600382 D-107 C2547 TC-063560 AB1009321 AB0013069 SAM002589962 PL001733 HY-14539 H482 LS-60881 CPD000058365 NCGC00022902-13 NCGC00022902-11 NCGC00022902-10 NCGC00022902-09 NCGC00022902-08 NCGC00022902-07 NCGC00022902-06 NCGC00022902-05 NCGC00022902-04 NCGC00022902-02 NCGC00015254-17 NCGC00015254-12 NCGC00015254-07 NCGC00015254-03 NCGC00015254-02 NCGC00015254-01 AKOS005064444 AR-1I2412 AC-280 5H-DIBENZO(B,E)(1,4)DIAZEPINE, 8-CHLORO-11-(4-METHYL-1-PIPERAZINYL)- HMS2092I16 HMS2089L13 HMS1989P12 HMS1921C16 HMS1791P12 HMS1569E21 HMS1361P12 BIO2_000790 BIO2_000310 BIO1_001414 BIO1_000925 BIO1_000436 QZUDBNBUXVUHMW-UHFFFAOYSA-N MOLPORT-001-728-041 NINDS_000343 LEX-123 KBIO3_002979 KBIO3_000620 KBIO3_000619 KBIO2_005735 KBIO2_005446 KBIO2_003167 KBIO2_002878 KBIO2_000599 KBIO2_000310 KBIO1_000343 HMS501B05 MLS001077282 MLS000028472 SPECTRUM1500685 SPBIO_002340 SPBIO_000798 CAS-5786-21-0 DIVK1C_000343 C6305_SIGMA CLOZAPINE [USAN:INN:BAN] KBIOSS_000599 KBIOSS_000310 KBIOGR_001336 KBIOGR_000310 CLOZAPINE (JAN/USP/INN) BRN 0764984 KS-1166 HF1854 LOPAC-C-6305 EINECS 227-313-7 SPECTRUM4_000898 SPECTRUM3_001828 SPECTRUM2_000919 PRESTWICK1_000350 PRESTWICK0_000350 AC1Q3ZWP AC1Q3OPZ AC1L1EJE TOCRIS-0444 SPECTRUM_000139 8-CHLORO-11-(4-METHYLPIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE HSDB 6478 3-CHLORO-6-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE 8-CHLORO-11-(4-METHYLPIPERAZINO)-5H-DIBENZO[B,E][1,4]DIAZEPINE 3B3-036001 W-105432 T7100235 D003024 SCHEMBL8397 GTPL38 J60AR2IKIC CLOZAPINE, CLOZARIL, AZALEPTIN, LEPONEX, FAZACLO, FROIDIR, DENZAPINE, ZAPONEX CID2818 KLOZAPOL AZALEPTIN CLORAZILREG S2459_SELLECK CHEBI:3766 CCRIS 9171 HF 1854 PRESTWICK_693 C18H19CLN4 CLOZARIL (TN) CLOZAPINA [INN-SPANISH] UNII-J60AR2IKIC CLOZAPINUM [INN-LATIN] W-801 CLOZAPINE(TAUTOMER) CLOZAPINUM CLORAZIL 135650115 38 178100616 [125I]αCGRP (HUMAN) Drug Info:
Drug Categories tranquilizing agents Drug Categories therapeutic uses Drug Categories serotonin antagonists Drug Categories serotonin agents Drug Categories psychotropic drugs Drug Categories psycholeptics Drug Categories physiological effects of drugs Drug Categories pharmacologic actions Drug Categories p-glycoprotein/abcb1 substrates Drug Categories neurotransmitter agents Drug Categories nervous system Drug Categories molecular mechanisms of pharmacological action Drug Categories moderate risk qtc-prolonging agents Drug Categories hypotensive agents Drug Categories hyperglycemia-associated agents Drug Categories heterocyclic compounds, 3-ring Drug Categories heterocyclic compounds Drug Categories gaba antagonists Drug Categories gaba agents Drug Categories dibenzazepines Drug Categories diazepines, oxazepines, thiazepines and oxepines Drug Categories cytochrome p-450 cyp3a4 substrates Drug Categories cytochrome p-450 cyp3a inhibitors Drug Categories cytochrome p-450 cyp3a inducers Drug Categories cytochrome p-450 cyp2e1 inhibitors Drug Categories cytochrome p-450 cyp2d6 substrates Drug Categories cytochrome p-450 cyp2d6 inhibitors (moderate) Drug Categories cytochrome p-450 cyp2d6 inhibitors Drug Categories cytochrome p-450 cyp2c9 substrates Drug Categories cytochrome p-450 cyp2c9 inhibitors Drug Categories cytochrome p-450 cyp2c8 substrates Drug Categories cytochrome p-450 cyp2c19 substrates Drug Categories cytochrome p-450 cyp2c19 inhibitors Drug Categories cytochrome p-450 cyp2a6 substrates Drug Categories cytochrome p-450 cyp1a2 substrates Drug Categories cytochrome p-450 cyp1a2 inhibitors (weak) Drug Categories cytochrome p-450 cyp1a2 inhibitors Drug Categories chemical actions and uses Drug Categories central nervous system depressants Drug Categories central nervous system agents Drug Categories antipsychotic agents (second generation [atypical]) Drug Categories antipsychotic agents Drug Categories antiemetics antagonists Drug Categories alpha1 antagonists Drug Groups approved Drug Type small molecule Drug Class antipsychotic agents Year of Approval 1989 FDA Approval 1989 Drug Class small molecule Drug Indications Antipsychotic Agents ATC n05ah(diazepines Drug Type drug/small molecule Publications:
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Mechanism of Interaction Serotonin 2a (5-HT2a) receptor antagonist Direct Interaction yes Trial Name - Publications:
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Alternate Names:
CLOZAPINE DrugBank Drug Name Clozapina Drug Synonym Clozapine Drug Synonym Drug Info:
Drug Type small molecule Drug Groups approved Drug Categories alpha1 antagonists Publications:
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CLOZAPINE Primary Drug Name Drug Info:
Year of Approval 1989 Drug Class antipsychotic agents Publications:
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LEPONEX Drug Trade Name LEPOTEX Drug Trade Name FAZACLO ODT Drug Trade Name Drug Info:
Drug Type drug/small molecule ATC n05ah(diazepines Publications:
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- Version: January-2014
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Drug Indications Antipsychotic Agents Drug Class small molecule FDA Approval 1989 Publications:
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C28936 NCI drug code Drug Info:
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- Version: 27-September-2017
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[125I]αCGRP (HUMAN) GuideToPharmacology Ligand Name 178100616 PubChem Drug SID Drug Info:
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HMS1921C16 Drug Synonym SPECTRUM_000139 Drug Synonym KBIOGR_000310 Drug Synonym Drug Info:
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CLOZAPINE pubchem_primary_name 2818 PubChem CID LEPONEX Drug Synonym Drug Info:
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CLOZAPINE GuideToPharmacology Ligand Name 135650115 PubChem Drug SID Drug Info:
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- Version: chembl_23
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