• CARBAMAZEPINE CHEMBL108 FDA Approved

    Alternate Names:

    Teril Ret
    Epimaz Ret
    Epimaz
    Timonil 400 Ret
    Carbamazepine
    Carbagen SR
    Timonil 200 Ret
    Tegretol Prolonged Release
    Arbil MR
    Tegretol Chewtab
    Sirtal Ret
    Carbatrol
    Tegretol
    G-32883
    Equetro
    Epitol
    Teril
    Tegretol Xr
    Tegretol-Xr
    C341
    FINLEPSIN
    NEUROTOL
    D00252
    TEGRETAL
    TEGRETOL CHEWTABS
    STAZEPINE
    PA448785
    3387
    2457
    BISTON
    CALEPSIN
    NU-CARBAMAZEPINE
    7847318
    TELESMIN
    CARBELAN
    0228-2143-10
    SIRTAL
    46507583
    CARBAMAZEPEN
    C1CCC2C(C1)C=CC3CCCCC3N2C(=O)N
    APO-CARBAMAZEPINE
    DB00564
    ATRETOL
    TIMONIL
    LEXIN
    DAP000129
    2554
    NOVO-CARBAMAZ
    KARBAMAZEPIN
    TARO-CARBAMAZEPINE
    TARO-CARBAMAZEPINE CR
    TEGRETOL CR
    C06868
    2241882
    CARBAMEZEPINE
    CARBAZEPINE
    STAZEPIN
    MOLPORT-000-710-574
    CARBAMAZEPINA
    NCGC00015234-03
    BSPBIO_001929
    LS-60362
    GEIGY 32883
    KBIOSS_000516
    EQUETRO (TN)
    HMS2091O19
    BRN 1246090
    KBIOGR_000724
    5H-DIBENZO[B,F]AZEPINE-5-CARBOXAMIDE
    CARBAZEPIN
    EINECS 206-062-7
    AMIZEPIN
    NCGC00023877-08
    LOPAC-C-4024
    AC-10560
    PRESTWICK0_000052
    C4024_SIGMA
    NCGC00023877-07
    SMR000058201
    LOPAC0_000292
    CARBAMAZEPIN
    BIM-0050280.0001
    EPITOL, EQUETRO, TEGRETOL, BISTON, CALEPSIN, CARBAMAZEPINE
    HMS640O02
    CHEMDIV1_018966
    5-CARBAMYLDIBENZO(B,F)AZEPINE
    S1693_SELLECK
    5-CARBAMYL-5H-DIBENZO(B,F)AZEPINE
    CID2554
    BPBIO1_000225
    C4024_SIAL
    HMS1920I17
    TRIMONIL
    SPECTRUM_000096
    CARBAMAZEPINE [USAN:INN:BAN:JAN]
    NSC 169864
    EU-0100292
    PRESTWICK1_000052
    298-46-4
    5H-DIBENZ[B,F]AZEPINE-5- CARBOXAMIDE
    SMR001227191
    DIVK1C_003750
    SPECTRUM1500159
    C 4024
    CARBAMAZEPINUM
    AC1Q4ZSU
    SAM002264603
    KBIO3_001149
    HMS1568K05
    5-CARBAMOYL-5H-DIBENZ[B,F]AZEPINE
    SPECTRUM4_000262
    BSPBIO_000203
    CARBAMAZEPINE (JP15/USP/INN)
    NCGC00023877-06
    CDS1_002710
    85756-57-6 (DI-HYDRATE)
    SPBIO_000170
    KBIO1_000388
    CARBATROL EXTENDED-RELEASE
    NCGC00015234-07
    BENZO[B][1]BENZAZEPINE-11-CARBOXAMIDE
    HMS501D10
    ZINC00004785
    MLS001055475
    IDI1_000388
    NCGC00023877-05
    5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE
    CARBAMAZEPINE, U.S.P.
    KBIO2_005652
    NCGC00015234-01
    AMIZEPINE
    MLS000069652
    CARBAMAZEPINUM [INN-LATIN]
    AKOS003235644
    DIVK1C_000388
    HMS2090M07
    STK177357
    NSC169864
    NCGC00015234-02
    WLN: T C676 BNJ BVZ
    CHEBI:3387
    CPD001227191
    KBIO2_003084
    SPECTRUM3_000325
    MLS001074172
    5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE
    BIPOTROL
    PRESTWICK3_000052
    C8981_SIAL
    PRESTWICK2_000052
    BRD-K71799949-001-06-7
    UNII-33CM23913M
    BIO-0751
    NCGC00015234-13
    HSDB 3019
    NCGC00023877-04
    NCHEM.859-COMP7
    5-CARBAMOYL-5H-DIBENZO(B,F)AZEPINE
    TEGRETOL (TN)
    NCGC00023877-03
    SPD-417
    SPBIO_002124
    CBCHROMO1_000350
    AC1L1DXT
    SPECTRUM5_000936
    5-CARBAMOYLDIBENZO(B,F)AZEPINE
    2-AZATRICYCLO[9.4.0.0^{3,8}]PENTADECA-1(11),3(8),4,6,9,12,14-HEPTAENE-2-CARBOXAMIDE
    AC1Q4ZSV
    PRESTWICK_104
    G 32883
    NEUROTOP RETARD
    KBIO2_000516
    CARBAMAZEPAN
    BIDD:GT0479
    OPREA1_790775
    CARBAMAZEPINA [INN-SPANISH]
    5-CARBAMOYL-5H-DIBENZ(B,F)AZEPINE
    NINDS_000388
    CARBAMAZEPINE (TEGRETOL)
    SPECTRUM2_000125
    CAS-298-46-4
    I06-0863
    AN-6325
    TEGRETOLREG
    AZAPENTACENE; SODIUM 5,12-DIHYDROAZAPENTACENE DISULFONATE; 5,12-DIHYDROQUINOXALINO[2,3-B]PHENAZINE SULFONATE SODIUM SALT
    2-AZATRICYCLO[9.4.0.0(3),?]PENTADECA-1(11),3(8),4,6,9,12,14-HEPTAENE-2-CARBOXAMIDE
    DIBENZO[B,F]AZEPINE-5-CARBOXYLIC ACID AMIDE(CARBAMAZEPINE)
    F0348-2551
    Q-200792
    3B2-1907
    3B2-1613
    A820074
    AB00051931-18
    NCGC00015234-19
    NCGC00015234-16
    NCGC00015234-15
    NCGC00015234-14
    NCGC00015234-12
    NCGC00015234-10
    NCGC00015234-09
    NCGC00015234-08
    NCGC00015234-06
    NCGC00015234-05
    NCGC00015234-04
    5H-DIBENZO[B,F]AZEPINE-5-CARBOXAMIDE #
    NSC-755920
    NSC-169864
    NC00679
    MCULE-9121567287
    LP00292
    KS-5146
    CS-2225
    33CM23913M
    TOX21_110104_1
    5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMINE
    11-BENZO[B][1]BENZAZEPINECARBOXAMIDE
    NSC755920
    CCG-38931
    BDBM50003659
    BBL005372
    TOX21_300195
    TOX21_202273
    TOX21_110104
    5-CARBOMOYL-5H-DIBENZO(B,F)AZEPINE
    HY-B0246
    ACT02606
    PHARMAKON1600-01500159
    HMS3372J13
    HMS3260L06
    HMS3259B21
    HMS3039K09
    HMS2233G16
    HMS2095K05
    MOLPORT-023-220-275
    DIBENZO[B,F]AZEPINE-5-CARBOXAMIDE
    CARBAMAZEPINE (JP16/USP/INN)
    AOB5783
    ZINC4785
    GTPL5339
    MLS002548877
    SCHEMBL21639
    IMINOSTILBENE-N-CARBOXAMIDE
    EPITOPE ID:174842
    TEGRETOL-CR
    2-AZATRICYCLO[9.4.0.0?,?]PENTADECA-1(11),3(8),4,6,9,12,14-HEPTAENE-2-CARBOXAMIDE
    VERSIZUR
    VERSITOL
    NEUROTOP
    ANLEPTIC
    CBZ
    DSSTOX_GSID_22731
    DSSTOX_RID_76704
    DSSTOX_CID_2731
    NCGC00015234-11
    FFGPTBGBLSHEPO-UHFFFAOYSA-N
    AB00051931-17
    H2605
    FT-0696814
    FT-0602927
    ST2418853
    KB-246109
    AB1009530
    AB0070254
    CARBAMAZEPINE-SUPPLIED BY SELLECK CHEMICALS
    ZB000594
    ST075773
    PL053430
    H495
    DR000542
    BC200975
    AK116064
    AJ-08230
    AJ-08227
    NCGC00259822-01
    NCGC00253982-01
    Teva-carbamazepine
    Tegretolxr XR
    Tegretol Chewtabs 200mg
    Tegretol Chewtabs 100mg
    Tegretol CR Tab 400mg
    Tegretol CR Tab 200mg
    Tegretol 200mg
    Tegretol - Sus 100mg/5ml
    Taro-carbamazepine Tab 200mg
    Taro-carbamazepine Chewable Tablets 200mg
    Taro-carbamazepine Chewable Tablets 100mg
    Taro-carbamazepine CR 400 mg
    Taro-carbamazepine CR 200 mg
    Sandoz-carbamazepine Chewtabs
    Sandoz-carbamazepine CR
    PMS-carbamazepine-CR
    PMS-carbamazepine CR
    PMS-carbamazepine
    PHL-carbamazepine CR
    Nu-carbamazepine Tab 200mg
    Mylan-carbamazepine CR
    Mazepine
    Dom-carbamazepine CR
    Dom-carbamazepine
    Carnexiv
    Carbamazepineer ER
    Carbamazepine-CR -(400mg)
    Carbamazepine-CR -(200mg)
    Carbamazepine ER
    Carbamazepine CR
    Carbamazepine 200mg Tablets
    Carbamazepine 200 Tab 200mg
    Carbamat
    Bio-carbamazepine
    Apo-carbamazepine CR
    Apo Carbamazepine Tab 200mg
    Actebral

    Drug Info:

    Year of Approval 1968
    Drug Class anticonvulsants
    ATC n03af(carboxamide derivatives)
    Drug Type drug/small molecule
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications for treatment of bipolar disorder
    Drug Categories tranquilizing agents
    Drug Categories therapeutic uses
    Drug Categories sensory system agents
    Drug Categories psychotropic drugs
    Drug Categories physiological effects of drugs
    Drug Categories pharmacologic actions
    Drug Categories peripheral nervous system agents
    Drug Categories p-glycoprotein/abcb1 substrates
    Drug Categories p-glycoprotein/abcb1 inhibitors
    Drug Categories p-glycoprotein/abcb1 inducers
    Drug Categories nervous system
    Drug Categories myelosuppressive agents
    Drug Categories molecular mechanisms of pharmacological action
    Drug Categories metabolic side effects of drugs and substances
    Drug Categories inducers of drug clearance
    Drug Categories heterocyclic compounds, 3-ring
    Drug Categories heterocyclic compounds
    Drug Categories drug-related side effects and adverse reactions
    Drug Categories dibenzazepines
    Drug Categories cytochrome p-450 enzyme inducers
    Drug Categories cytochrome p-450 cyp3a4 substrates
    Drug Categories cytochrome p-450 cyp3a4 inducers (strong)
    Drug Categories cytochrome p-450 cyp3a inducers
    Drug Categories cytochrome p-450 cyp2c9 inducers (strong)
    Drug Categories cytochrome p-450 cyp2c9 inducers
    Drug Categories cytochrome p-450 cyp2c8 substrates
    Drug Categories cytochrome p-450 cyp2c8 inducers (strong)
    Drug Categories cytochrome p-450 cyp2c8 inducers
    Drug Categories cytochrome p-450 cyp2c19 inhibitors
    Drug Categories cytochrome p-450 cyp2c19 inducers (strong)
    Drug Categories cytochrome p-450 cyp2c19 inducers
    Drug Categories cytochrome p-450 cyp2b6 inducers (strong)
    Drug Categories cytochrome p-450 cyp2b6 inducers
    Drug Categories cytochrome p-450 cyp1a2 substrates
    Drug Categories cytochrome p-450 cyp1a2 inhibitors
    Drug Categories cytochrome p-450 cyp1a2 inducers (strong)
    Drug Categories cytochrome p-450 cyp1a2 inducers
    Drug Categories combined inducers of cyp3a4 and p-glycoprotein
    Drug Categories chemically-induced disorders
    Drug Categories chemical actions and uses
    Drug Categories central nervous system depressants
    Drug Categories central nervous system agents
    Drug Categories carboxamide derivatives
    Drug Categories antimanic agents
    Drug Categories anticonvulsants
    Drug Categories analgesics, non-narcotic
    Drug Categories analgesics
    Drug Groups investigational
    Drug Groups approved
    Drug Type small molecule
    (5 More Sources)

    Publications:

    Yang et al., 2002, Inhibition of Na(+) current by imipramine and related compounds: different binding kinetics as an inactivation stabilizer and as an open channel blocker., Mol. Pharmacol.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Lipkind et al., 2010, Molecular model of anticonvulsant drug binding to the voltage-gated sodium channel inner pore., Mol. Pharmacol.
    Yang et al., 2010, Lidocaine, carbamazepine, and imipramine have partially overlapping binding sites and additive inhibitory effect on neuronal Na+ channels., Anesthesiology
    Kim et al., 2007, A 6-month longitudinal study of bone mineral density with antiepileptic drug monotherapy., Epilepsy Behav
    Faucette et al., 2004, Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers., Drug Metab. Dispos.
    Usui et al., 2003, Induction of CYP3As in HepG2 cells by several drugs. Association between induction of CYP3A4 and expression of glucocorticoid receptor., Biol. Pharm. Bull.
    Alfirevic et al., 2006, HLA-B locus in Caucasian patients with carbamazepine hypersensitivity., Pharmacogenomics
    Isojärvi et al., Effects of carbamazepine therapy on serum sex hormone levels in male patients with epilepsy., Epilepsia
    Bonuccelli et al., 1985, Effects of carbamazepine on prolactin secretion in normal subjects and in epileptic subjects., Clin Neuropharmacol
    Himmerich et al., 2005, Plasma levels of leptin and endogenous immune modulators during treatment with carbamazepine or lithium., Psychopharmacology (Berl.)
    Tutor-Crespo et al., [A study of some indirect biochemical markers in the evaluation of enzymatic induction caused by antiepileptic drugs]., Rev Neurol