• CAPSAICIN CHEMBL294199 FDA Approved

    Alternate Names:

    Zostrix HP
    Zostrix
    Capsaicin
    Zacin
    Qutenza
    C339
    53801090
    2486
    D002211
    MEDICIS BRAND OF CAPSAICIN
    HSDB 954
    NCHEMBIO.146-COMP1
    BSPBIO_002917
    S1990_SELLECK
    NONENAMIDE, N-((4-HYDROXY-3-METHOXYPHENYL)METHYL)-8 -METHYL-, (E)-
    BRN 2816484
    CASWELL NO. 158
    HMS1791N10
    SMP2_000337
    (6E)-N-{[4-HYDROXY-3-(METHYLOXY)PHENYL]METHYL}-8-METHYLNON-6-ENAMIDE
    6-NONENAMIDE, N-((4-HYDROXY-3-METHOXYPHENYL)METHYL)-8-METHYL-, (E)-
    NCGC00090853-09
    BSPBIO_001548
    NONENAMIDE, 8-METHYL-N-VANILLYL-, (E)-
    NGX-4010
    M1149
    CARTER HORNER BRAND OF CAPSAICIN
    AXSAIN
    BRD-K50590187-001-06-6
    8 METHYL N VANILLYL 6 NONENAMIDE
    8-METHYL-N-VANILLYL-TRANS-6-NONENAMIDE
    NGX-7325
    ANTIPHLOGISTINE RUB A-535 CAPSAICIN
    AC1Q46B3
    HMS1361N10
    GELCEN
    LINK BRAND OF CAPSAICIN
    N-[(4-HYDROXY-3-METHOXY-PHENYL)METHYL]NONANAMIDE
    CENTRUM BRAND OF CAPSAICIN
    CAPSIN
    LS-2138
    (E)-CAPSAICIN
    404-86-4
    HMS2092D21
    MLS002154049
    MOLPORT-001-742-263
    N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE
    SPECTRUM1501128
    HMS1570P19
    NGX4010
    UNII-S07O44R1ZM
    (E)-8-METHYL-N-VANILLYL-6-NONENAMIDE
    CAPSAICIN (IN OLEORESIN OF CAPSICUM)
    CAPSAICIN PATCH
    BPBIO1_001053
    N-(4-HYDROXY-3-METHOXYBENZYL)-8-METHYLNON-TRANS-6-ENAMIDE
    912457-62-6
    FLEMMING BRAND OF CAPSAICIN
    NCHEMBIO862-COMP2
    UPCMLD-DP092:001
    21750_SIGMA
    PRESTWICK3_000879
    BIO-0615
    12084_FLUKA
    KATRUM
    BSPBIO_000957
    CAPSAICIN (NATURAL)
    SMR000718774
    ZOSTRIX (TN)
    CAPZASIN
    360376_ALDRICH
    DCL000737
    HMS2089N11
    1548943
    EINECS 206-969-8
    6-NONENAMIDE, N-((4-HYDROXY-3-METHOXYPHENYL)METHYL)-8-METHYL-, (6E)-
    TRANSACIN
    NEUROTOXIC
    6-NONENAMIDE, 8-METHYL-N-VANILLYL-, (E)-
    NCGC00090853-03
    PRESTWICK_204
    C-1700
    CAPSAICINE
    E-CAPSAICIN
    CAPSAICIN (JAN/USP)
    CHEBI:3374
    MR3H3
    CAPSAICIN [USAN]
    ALACAN BRAND OF CAPSAICIN
    N-(4-HYDROXY-3-METHOXYBENZYL)-8-METHYL-6-NONENAMIDE
    IDI1_000354
    NGX-1998
    ELAN BRAND OF CAPSAICIN
    ISODECENOIC ACID VANILLYLAMIDE
    21750_FLUKA
    6-NONENAMIDE, 8-METHYL-N-VANILLYL-, (E)- (8CI)
    HMS1921H11
    NGX 4010
    SMALLER BRAND OF CAPSAICIN
    NCGC00090853-08
    HMS501B16
    21748_FLUKA
    NSC56353
    FT-0082538
    C18H27NO3
    D00250
    M2028_SIGMA
    NCGC00090853-07
    (E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYLNON-6-ENAMIDE
    FEMA NO. 3404
    6-NONENAMIDE, N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-, (E)-
    360376_SIGMA
    TL8002946
    AC1LU7K3
    THOMPSON BRAND OF CAPSAICIN
    EPA PESTICIDE CHEMICAL CODE 070701
    (6E)-N-(4-HYDROXY-3-METHOXYBENZYL)-8-METHYLNON-6-ENAMIDE
    NCI-C56564
    VINAS BRAND OF CAPSAICIN
    NGX-3781
    TRANS-CAPSAICIN
    TRANS-8-METHYL-N-VANILLYL-6-NONENAMIDE
    BRD-K37056290-001-01-1
    NCGC00090853-01
    UPCMLD-DP092
    CCRIS 1588
    MEGXP0_001448
    HMS1989N10
    NCGC00090853-02
    ZINC01530575
    PRESTWICK2_000879
    CID1548943
    DEPLETES SUBSTANCE P
    NCGC00090853-04
    NCGC00090853-06
    N-((4-HYDROXY-3-METHOXYPHENYL)METHYL)-8-METHYL-6-NONENAMIDE, (E)-
    N-(4-HYDROXY-3-METHOXYBENZYL)-8-METHYLNON-6-ENAMIDE
    CAPSAICIN [IN OLEORESIN OF CAPSICUM]
    CAPSIDOL
    21748_SIGMA
    8-METHYL-N-VANILLYL-6-NONENAMIDE
    IDI1_034018
    8-METHYL-N-VANILLYL-6-NONENAMIDE, (E)-
    I01-2469
    6-NONENAMIDE, (E)-N-((4-HYDROXY-3-METHOXY-PHENYL)METHYL)-8-METHYL
    NSC 56353
    C06866
    TQ-1018
    UPCMLD-DP092:002
    49688535
    CAPSICUM FARMAYA
    SPECTRUM5_000538
    STYPTYSAT
    CAPSAICIN (2444-46-4 NONIVAMIDE (SYNTHETIC CAPSAICIN))
    SDCCGMLS-0066678.P001
    Zostrix Original Strength
    Zostrix Joint and Arthritis Pain Relief
    Zostrix Hot and Cold Therapy System
    Zostrix High Potency Foot Pain Relief
    Zostrix Foot Pain Relief
    Ziks Arthritis Pain Relief
    Yunnan Baiyao Arthritis Pain Relief
    Xyphex Biofrequency Chip
    Xoten-C
    Wellpatch Warming Pain Relief
    Wellpatch Capsaicin Pain Relief
    Wellness Products Victorx
    Wellness Products J-flex
    Weh-weh Natural Pain Relief Oil
    Walgreens Capsaicin Hot
    Vantelin Hot Pain Relieving Gel Patch Large
    Vantelin Hot Pain Relieving Gel Patch
    Ultracin
    Ultra Therapy Pain Relief
    Ultimate Topical Pain Relief Patch
    True Pain Relief Plus
    Triple Action Arthritis
    Transanosil
    Rock Sauce
    Rite Aid Capsicum Hot
    Rezil
    Retadolor Pain Relief
    Renovo Lido5
    Renovo
    Reme D
    Remaxazon External Patch
    Relyyt Patch
    Reliever
    Reliaderm
    Releevia Mc
    Releevia
    Pure Relief Penetrating Pain Relief
    Pure Relief
    Pure Pain Relief
    Preferred Plus Arthritis Cream
    Perform Atomic Heat
    Parche Leon Milagroso Dual Action
    Parche Leon Milagroso
    Paraid Hot Capsicum
    Pallerix Otc Biofrequency Chip
    Pallerix
    Painmd Max
    Painkoolers Topical Analgesic Patch
    Painkoolers Topical Analgesic
    Painkoolers
    Painazin Cp
    Pain Relieving Roll-ON
    Pain Relieving
    Pain Relief Patch
    Overtime-X
    Overtime
    Outdoor Hands
    Omega 3 Heat Therapy
    Omega 3
    Nopiate Topical Pain Relief
    New Terocin
    My Omega Heat Therapy
    Muscular Balm
    Moisturizing Glucosamine Brand
    Miracle Plus Overnight Pain Relieving
    Miracle Plus Neck and Shoulder Pain Relief
    Menthol, Capsaicin
    Menthocin Patch With Lidocaine - Strong
    Menthacin Lotion
    Menthacin - Cream
    Mendex
    Mencaps
    Meijer Capsaicin
    Megrix Otc
    Megrix
    Medrox-RX
    Medrox
    Medicated Heat
    Medi-sulting Topical Pain Relief
    Medi-patch With Lidocaine Rx
    Medi-patch With Lidocaine
    Medi-derm Topical Pain Relief
    Medi-derm Rx
    Medi-derm / L With Lidocaine Rx
    Medi-derm / L With Lidocaine
    Mac Patch
    Livrelief Pain Relief
    Lidopro
    Lido-RX 4.1
    Lexicaps
    Levatio Patch
    Leader Capsaicin
    Lcdo. Orlando Rivera Arthritis Topical Analgesic
    Labella Linimento Obrero
    Kool Heat Pain Therapy
    Kerasal Neurocream
    Invisible Pain
    Hurt Blocker Pro Pain Relief
    Hot Spot Point Relief
    Hot Pain Relieving
    Heet Liniment Liq
    Good Neighbor Pharmacy Capsaicin
    Good Neighbor Pharmacy Arthritis Pain Relief
    Glacierix
    Genorthix Pain Relieving Roll On
    Gellert Joint Care
    Fyzical Sports Pain Relief 2 Mild
    Fyzical Sports Pain Relief 1-cool
    Fyzical Sports Pain Relief
    Flexxsonic Pain Relief
    Flexin
    Flex-OL
    Flanax
    Fesi
    Fast Arthritis Aid Pain Relieving
    Family Care Thera Flex Pain
    Family Care Arthritis Pain Relief
    Extra Strength Pain Reliever
    External Analgesic
    Exoten-C
    Emu Essentials Brand Pain Relieving
    Earths Care Arthritis Cream
    Eagle
    Dusel Warm Arthritis Dead Sea Salt Therapy
    Dr.'s Cream
    Dr. Oh Balm
    Dr. Harveys Herbal Motion Pain Formula
    Doloracin/l Rx With Lidocaine
    Doloracin Rx
    Dolor-parche With Lidocaine-RX
    Dingtai Pharmatopical Analgesic
    Dendracin Neurodendraxcin
    Cvs Medicated Heat 1 Ct
    Cvs Capsaicin
    Corisin Arthritis Pain Relief
    Coralite Topical Analgesic Capsaicin Heat
    Coralite Pain Relief
    Coralite Muscle and Joint Pain Relief
    Coralite Medicated Heat
    Copperfixx
    Cmx Topical Pain
    Careone Arthritis Pain Relief
    Capzasin-P Creme - 0.025%
    Trans-D
    Topical Pain Relief Rx
    Topical Pain Relief
    Tianhe Zhuifeng Gao
    Tianhe Gutong Tiegao (in Polyisobutylene Carrier)
    Tianhe Gutong Tiegao
    Therapy Pain
    Therapatch Warm
    Terocin
    Synovium Pain Relieving Gel
    Sure Relief SR Relief
    Super Arthritis Pain Relief
    Soothee Patch
    Soothanol X2
    Simanix
    Silvera Pain Relief Patch
    Sherman and Clark Pain Relieving
    Screamin Hot Toast
    Satogesic Hot
    Rugby Capsaicin External Analgesic
    Rub A535 Capsaicin
    Rotex
    Capzasin Quick Relief
    Capzasin P Arthritis Pain Relief
    Capzasin No Mess Applicator
    Capzasin Hp Arthritis Pain Relief
    Capsodan Cream
    Capsiderm
    Capsaicin Regular Cream
    Capsaicin Pain Relief
    Capsaicin No-fuss Applicator
    Capsaicin Mild Cream
    Capsaicin Forte Cream
    Capsaicin Cream 0.025%
    Capsaicin Arthritis Pain Relief Cream
    Capment
    Cajun Hot Ice Muscle and Joint Pain Rub
    Born Again Super Pain Relieving Lotion
    Blue Ice Pain Relieving
    Biomega Heat Pain Therapy
    Biomega
    Bioaches
    Bio-mega Heat Therapy
    Benejoint
    Bb Medicated Pain Relieving Oil
    Astrapharm Chilli Brand External Medicated
    Assured Pain Relief Hot Patch
    Assured Pain Relief Hot Menthol
    Arthur Itis Cream
    Arthritis Pain Reliever
    Arthritis Pain Relief
    Arthritis Extra Strength Roll-ON Lotion
    Arthritic Pain Relief
    Arthritazin Pain Relieving Ez
    Arthritazin Pain Relieving
    Arthricare for Women Ultra Strength
    Arthricare for Women Quick Drying
    Arthricare for Women Extra Moisturizing
    Apanol Linimento Obrero
    Antiphlogistine Rub A-535 Capsaicin Liquid
    Antiphlogistine Rub A-535 Capsaicin Gel
    Anodynerx
    Allevess
    Alivio Medicated Pain
    Alivio
    Alegenix Biofrequency Chip
    Aflexeryl-MC
    Adazin
    DB06774
    3B3-082299
    TRANS-N-((4-HYDROXY-3-METHOXYPHENYL)METHYL)-8-METHYL-6-NONENAMIDE
    (E)-N-[(4-HYDROXY-3-METHOXY-PHENYL)METHYL]-8-METHYL-NON-6-ENAMIDE
    (6E)-N-(4-HYDROXY-3-METHOXYBENZYL)-8-METHYL-6-NONENAMIDE #
    N-(3-METHOXY-4-HYDROXYBENZYL)-8-METHYL-6-NONENAMIDE
    AB00053098-11
    W-5044
    (E)-8-METHYL-N-VANILLYL-6-NONENAMIDE(8CL)
    N1667
    FT-0664231
    FT-0638549
    FT-0600038
    4CH-016296
    TC-030399
    ST057183
    N735
    LP003278
    HY-10448
    CJ-23980
    CAS_404-86-4
    BT000467
    AN-23437
    AK113598
    AJ-26667
    NCGC00257869-01
    NCGC00090853-12
    NCGC00090853-11
    NCGC00090853-10
    NCGC00017337-13
    NCGC00017337-12
    NCGC00017337-11
    NCGC00017337-10
    NCGC00017337-09
    NCGC00017337-08
    NCGC00017337-07
    NCGC00017337-06
    NCGC00017337-05
    NCGC00017337-04
    NCGC00017337-03
    RTC-030399
    NSC-757844
    MCULE-8056866140
    KS-5181
    DB05318
    CS-1518
    CAPSAICIN-SUPPLIED BY SELLECK CHEMICALS
    AKOS007930159
    (E)8-METHYL-N-VANILLYL-6-NONENAMIDE
    (E)-N-(4-HYDROXY-3-METHOXYBENZYL)
    STL372889
    NSC757844
    NSC-56353
    EI-125
    CCG-39908
    CC0144
    BBL027836
    TOX21_200315
    TOX21_110817
    ZINC1530575
    NSC_2548
    PHARMAKON1600-01501128
    HMS3649N15
    HMS3402N10
    HMS2230O23
    HMS2097P19
    HMDB02227
    BDBM86537
    BDBM20461
    (E)-N-(4-HYDROXY-3-METHOXYBENZYL)-8-METHYLNON-6-ENAMIDE
    QUTENZA, VANILLOID, CAPSAICIN
    DSSTOX_GSID_20241
    DSSTOX_RID_75455
    DSSTOX_CID_241
    (6E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYLNON-6-ENAMIDE
    NCGC00017337-02
    YKPUWZUDDOIDPM-SOFGYWHQSA-N
    S07O44R1ZM
    GTPL2486
    CAPSAICIN, FROM NATURAL SOURCE
    TRANS-8-METHYL-N-VANILLYLNON
    SCHEMBL8086
    SCHEMBL8085
    6-NONENAMIDE, (E)-
    CAPSAICINOIDS
    CAS-404-86-4
    CAPSAICIN(QUTENZA)
    CAPSAICIN [USP]
    EPSILON-CAPSAICIN
    TNP00277
    ADLEA
    N-((4-HYDROXY-3-METHOXYPHENYL)METHYL)-8-METHYL-6-NONENAMIDE
    MIOTON
    VANILLOID
    N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYLNON-6-ENAMIDE
    CAPSICINE
    CAPSICIN
    QUTENZAREG
    ISODECENOATE
    C1955

    Drug Info:

    Drug Categories therapeutic uses
    Drug Categories solanaceous alkaloids
    Drug Categories sensory system agents
    Drug Categories polyunsaturated alkamides
    Drug Categories physiological effects of drugs
    Drug Categories phenols
    Drug Categories pharmacologic actions
    Drug Categories peripheral nervous system agents
    Drug Categories organic chemicals
    Drug Categories nervous system
    Drug Categories lipids
    Drug Categories hydrocarbons, cyclic
    Drug Categories hydrocarbons, aromatic
    Drug Categories hydrocarbons, acyclic
    Drug Categories hydrocarbons
    Drug Categories heterocyclic compounds
    Drug Categories fatty acids, unsaturated
    Drug Categories fatty acids, monounsaturated
    Drug Categories fatty acids
    Drug Categories dermatologic agents
    Drug Categories cytochrome p-450 cyp3a inhibitors
    Drug Categories cytochrome p-450 cyp2e1 substrates
    Drug Categories cytochrome p-450 cyp1a2 inducers
    Drug Categories chemical actions and uses
    Drug Categories catechols
    Drug Categories benzene derivatives
    Drug Categories antipruritics
    Drug Categories anesthetics, local
    Drug Categories anesthetics
    Drug Categories amides
    Drug Categories alkynes
    Drug Categories alkenes
    Drug Categories alkaloids
    Drug Groups approved
    Drug Type small molecule
    FDA Approval approved
    FDA Approval not approved (orphan status)
    Drug Class Small molecule
    Drug Indications analgesic
    (4 More Sources)

    Publications:

    Anand et al., 2011, Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch., Br J Anaesth
    Wallace et al., 2011, Qutenza®: a capsaicin 8% patch for the management of postherpetic neuralgia., Expert Rev Neurother
    Han et al., 2006, Effects of capsaicin on P-gp function and expression in Caco-2 cells., Biochem. Pharmacol.
    Mannion et al., 1999, Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity., Proc. Natl. Acad. Sci. U.S.A.
    Reilly et al., 2003, Metabolism of capsaicin by cytochrome P450 produces novel dehydrogenated metabolites and decreases cytotoxicity to lung and liver cells., Chem. Res. Toxicol.
    Oikawa et al., 2006, Mechanism of oxidative DNA damage induced by capsaicin, a principal ingredient of hot chili pepper., Free Radic. Res.
    Lee et al., 2007, Capsaicin promotes the development of burst-forming units--erythroid (BFU-E) from mouse bone marrow cells., Exp. Mol. Med.
    Okere et al., 2004, Capsaicin increases GFAP and glutamine synthetase immunoreactivity in rat arcuate nucleus and median eminence., Neuroreport
    Knight et al., 1997, Localization of leukaemia inhibitory factor to airway epithelium and its amplification of contractile responses to tachykinins., Br. J. Pharmacol.
    Joung et al., 2007, Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target., Antioxid. Redox Signal.
    Sweeney et al., 1989, Morphine, capsaicin and K+ release purines from capsaicin-sensitive primary afferent nerve terminals in the spinal cord., J. Pharmacol. Exp. Ther.
    Malcangio et al., 2000, Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord., Eur. J. Neurosci.
    Wilson-Gerwing et al., 2005, Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons., J. Neurosci.
    Kim et al., 1997, Proliferation and repair of guinea pig tracheal epithelium after neuropeptide depletion and injury in vivo., Am. J. Physiol.
    Sharkey et al., 1999, Immediate-early gene expression in the inferior mesenteric ganglion and colonic myenteric plexus of the guinea pig., J. Neurosci.
    Suzuki et al., 1985, Regional distribution of a novel pituitary protein (7B2) in the rat spinal cord: effect of neonatal capsaicin treatment and thoracic cord transection., Neurosci. Lett.