• AT-9283 CHEMBL495727 Antineoplastic

    Alternate Names:

    AT-9283
    PYRAZOLE-BENZIMIDAZOLE UREA ANALOGUE, 16
    CID11496629
    CID 11496629
    DCL001068
    1-CYCLOPROPYL-3-[(3Z)-3-[5-(MORPHOLIN-4-YLMETHYL)BENZIMIDAZOL-2-YLIDENE]-1,2-DIHYDROPYRAZOL-4-YL]UREA
    1-CYCLOPROPYL-3-[(3E)-3-[5-(MORPHOLIN-4-YLMETHYL)BENZIMIDAZOL-2-YLIDENE]-1,2-DIHYDROPYRAZOL-4-YL]UREA
    1-CYCLOPROPYL-3-(3-(6-(MORPHOLINOMETHYL)-1H-BENZO[D]IMIDAZOL-2-YL)-1H-PYRAZOL-4-YL)UREA
    BRD-K24576554-001-01-4
    W-5568
    AK-43760
    QC-4297
    BCP9000337
    AT9283-SUPPLIED BY SELLECK CHEMICALS
    AKOS016006006
    DCL000059
    BCPP000379
    MOLPORT-009-679-504
    SCHEMBL15005492
    GTPL7949
    CC-56
    S1134_SELLECK
    AT9283, AT-9283
    AT-9283, AT 9283, 896466-04-9
    11696609
    UREA, N-CYCLOPROPYL-N'-(3-(6-(4-MORPHOLINYLMETHYL)-1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL)-
    35R
    N-CYCLOPROPYL-N'-[3-[5-(4-MORPHOLINYLMETHYL)-1H-BENZIMIDAZOL-2-YL]-1H-PYRAZOL-4-YL]UREA
    1-CYCLOPROPYL-3-{3-[5-(MORPHOLIN-4-YLMETHYL)-1H-BENZIMIDAZOL-2-YL]-1H-PYRAZOL-4-YL}UREA
    X7478
    DB-078462
    AB0033752
    HY-50514
    CS-0107
    RS0013
    3-CYCLOPROPYL-1-{3-[5-(MORPHOLIN-4-YLMETHYL)-1H-1,3-BENZODIAZOL-2-YL]-1H-PYRAZOL-4-YL}UREA
    SYN1011
    BDBM27087
    SCHEMBL15005494
    SCHEMBL545809
    XAV9KYN9WL
    1-CYCLOPROPYL-3-(3-(5-(MORPHOLINOMETHYL)-1H-BENZO[D]IMIDAZOL-2-YL)-1H-PYRAZOL-4-YL)UREA
    C19H23N7O2
    896466-04-9
    AT 9283
    UNII-XAV9KYN9WL
    11496629
    AT9283
    KB-74758
    3-CYCLOPROPYL-1-{3-[5-(MORPHOLIN-4-YLMETHYL)-1,3-BENZODIAZOL-2-YLIDENE]-1,2-DIHYDROPYRAZOL-4-YL}UREA
    1-CYCLOPROPYL-3-[3-(5-MORPHOLIN-4-YLMETHYL-1H-BENZOIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]-UREA
    SMR004702836
    HE408637
    HE065774
    AJ-97300
    NCGC00346493-01
    ZINC38995988
    ANW-69120
    HMS3244P09
    HMS3244O10
    HMS3244O09
    LOLPPWBBNUVNQZ-UHFFFAOYSA-N
    CTK8C2842
    MLS006011044
    56965909
    DB05169
    249565632
    7949

    Drug Info:

    Drug Categories protein kinase inhibitors
    Drug Categories organic chemicals
    Drug Categories heterocyclic compounds, 2-ring
    Drug Categories heterocyclic compounds
    Drug Groups investigational
    Drug Type small molecule
    Drug Class Kinase Inhibitors
    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications antineoplastic agent
    (6 More Sources)

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase JAK2 inhibitor
    Direct Interaction yes
    Specific Action of the Ligand Inhibition

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase JAK3 inhibitor
    Direct Interaction yes
    Specific Action of the Ligand Inhibition

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Trial Name AT9283
    Novel drug target Novel Target
    Notes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase ABL inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase receptor FLT3 inhibitor
    Direct Interaction yes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Notes

    Publications:

    • Version: 5.0.8

    Alternate Names:
    AT9283 DrugBank Drug Name

    Drug Info:
    Drug Type small molecule
    Drug Groups investigational
    Drug Categories heterocyclic compounds

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    AT9283 Development Name

    Drug Info:
    Drug Class Kinase Inhibitors

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antineoplastic agent
    Drug Class Small molecule
    FDA Approval not approved

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    DCL001068 TTD Drug Id
    AT-9283 Primary Drug Name
    AT-9283 Drug Synonym

    Drug Info:

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    AT9283 pubchem_primary_name
    11496629 PubChem CID
    UNII-XAV9KYN9WL Drug Synonym

    Drug Info:

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    896466-04-9 pubchem_primary_name
    56965909 PubChem CID
    AT9283 Drug Synonym

    Drug Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    AT-9283 GuideToPharmacology Ligand Name
    249565632 PubChem Drug SID

    Drug Info:

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    AT9283 Primary Drug Name
    DCL000059 TTD Drug Id

    Drug Info:

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    AT9283 Primary Drug Name
    AT9283 Drug Synonym

    Drug Info:

    Publications:

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications: