• AMILORIDE CHEMBL945 FDA ApprovedAntineoplastic

    Alternate Names:

    BDBM16173
    Amiloride
    Midamor
    Hydro-Ride
    137053-86-2
    3,5-DIAMINO-6-CHLORO-N-(DIAMINOMETHYLENE)PYRAZINAMIDE;HYDROCHLORIDE
    3,5-DIAMINO-N-CARBAMIMIDOYL-6-CHLORO-PYRAZINE-2-CARBOXAMIDE
    N-AMIDINO 3,5-DIAMINO-6-CHLORO-2-PYRAZINECARBOXAMIDE
    117188-EP2298776A1
    117188-EP2277879A1
    AB00053415-25
    AB00053415-24
    N-AMIDINO-3,5-DIAMINO-6-CHLOROPYRAZINAMIDE
    (3,5-DIAMINO-6-CHLOROPYRAZINOYL)GUANIDINE
    U460
    NCGC00015089-17
    NCGC00015089-16
    NCGC00015089-15
    NCGC00015089-14
    NCGC00015089-13
    NCGC00015089-11
    NCGC00015089-09
    NCGC00015089-07
    NCGC00015089-06
    NCGC00015089-05
    NCGC00015089-04
    NCGC00015089-03
    MCULE-5948863568
    CS-2297
    CCG-204206
    TOX21_110080_1
    AKOS015961348
    STL373007
    SBB037856
    DAP000187
    CPD-10324
    BBL028157
    TOX21_110080
    ZINC4340269
    HY-B0285
    ACT05652
    ACT05635
    HMS3355K04
    HMS2213E05
    MOLPORT-005-937-651
    GTPL2421
    SCHEMBL27562
    7DZO8EB0Z3
    CID16231
    ARUMIL
    (3,5-DIAMINO-6-CHLOROPYRAZIN-2-YL)-N-(???METHYL)CARBOXAMIDE
    MODURET
    AMILORID
    AMICLARAN
    MIDAMORREG
    SMR000449325
    CAS-2609-46-3
    PYRAZINECARBOXAMIDE, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-, MONOHYDROCHLORIDE
    3,5-DIAMINO-N-[AMINO(IMINO)METHYL]-6-CHLOROPYRAZINE-2-CARBOXAMIDE
    MLS000758249
    AMILORIDE (SEE ALSO: AMILORIDE HCL (2016-88-8))
    N-AMIDINO-3,5-DIAMINO-6-CHLORO-2-PYRAZINECARBOXAMIDE
    BRD-K97181089-310-03-0
    BRD-K97181089-003-02-3
    DSSTOX_GSID_43853
    AMILORIDE HYDROCHOLRIDE
    DSSTOX_RID_80077
    DSSTOX_CID_23853
    D07447
    C06821
    AMIPRAMIDINE
    AB00053415
    SMR000486264
    AC-13631
    NCGC00024443-09
    NCGC00024443-07
    NCGC00024443-06
    NCGC00024443-05
    NCGC00024443-02
    NCGC00015089-12
    NCGC00015089-08
    NCGC00015089-02
    NCGC00015089-01
    IDI1_034042
    IDI1_000182
    2016-88-8 (ANHYDROUS HYDROCHLORIDE)
    LS-1094
    DB00594
    ZINC04340269
    AMILORIDE HYDROCHLORIDE HYDRATE
    MK-870 (HYDROCHLORIDE DIHYDRATE)
    HMS2089H05
    HMS1989O14
    HMS1791O14
    BIO2_000772
    BIO2_000292
    BIO1_001337
    BIO1_000848
    BIO1_000359
    3,5-DIAMINO-6-CHLORO-N-(DIAMINOMETHYLIDENE)PYRAZINE-2-CARBOXAMIDE
    17440-83-4 (HYDROCHLORIDE)
    XSDQTOBWRPYKKA-UHFFFAOYSA-N
    N-AMIDINO-3,5-DIAMINO-6-CHLORPYRAZINCARBOXAMID
    MOLPORT-005-934-472
    NINDS_000182
    MIDAMOR (HYDROCHLORIDE DIHYDRATE)
    KBIO3_001326
    KBIO3_000584
    KBIO3_000583
    KBIO2_005530
    KBIO2_005428
    KBIO2_002962
    KBIO2_002860
    KBIO2_000394
    KBIO2_000292
    KBIO1_000182
    BCBCMAP01_000101
    AMIKAL (HYDROCHLORIDE DIHYDRATE)
    3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE
    BPBIO1_000015
    MLS001060798
    SPBIO_001934
    SPBIO_000136
    DIVK1C_000182
    BIDD:GT0466
    ST079279
    KBIOSS_000394
    KBIOSS_000292
    KBIOGR_000544
    KBIOGR_000292
    BSPBIO_001826
    BSPBIO_001572
    BSPBIO_000013
    LOPAC0_000111
    AC1L27IZ
    PYRAZINECARBOXAMIDE, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-
    LOPAC-A-7410
    EINECS 220-024-7
    SPECTRUM5_000776
    SPECTRUM4_000132
    SPECTRUM3_000293
    SPECTRUM2_000118
    PRESTWICK3_000007
    PRESTWICK2_000007
    PRESTWICK1_000007
    PRESTWICK0_000007
    AC1Q3POC
    AMILORIDE [INN:BAN]
    1F5L
    TOCRIS-0890
    SPECTRUM_000034
    N-AMIDINO-3,5-DIAMINO-6-CHLOROPYRAZINECARBOXAMIDE
    CHEBI:2639
    CCRIS 6545
    3,5-DIAMINO-N-CARBAMIMIDOYL-6-CHLOROPYRAZINE-2-CARBOXAMIDE
    AMILORIDE (INN)
    AMICLARAN (TN)
    UNII-7DZO8EB0Z3
    AMIPRAZIDINE
    AMILORIDE HCL
    AMILORIDA [INN-SPANISH]
    2609-46-3
    AMILORIDUM [INN-LATIN]
    AMYLORIDE
    AMILORIDUM
    AMILORIDA
    GUANAMPRAZIN
    AMIPRAMIZIDE
    AMIPRAMIZID
    GUANAMPRAZINE
    AMIPRAMIDIN
    16231
    C6H8CLN7O
    9039
    2016-88-8
    135649936
    2421

    Drug Info:

    Year of Approval 1981
    Drug Class antihypertensive agents
    Drug Class diuretics
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications antihypertensive agent
    (2 More Sources)

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? True

    Publications:

  • Interaction Types:
    inhibitor

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    Publications:

  • Interaction Types:
    blocker

    Interaction Info:
    Trial Name HTI-101
    Novel drug target Established target

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction ASIC1b
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    channel blocker

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction transient component only - sustained component enhanced by 200μM amiloride at pH 4
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name HTI-101
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name HTI-101
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name HTI-101
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Drug family Na-Ca chanel blocker
    Alteration KCNJ5:L168R

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    AMILORIDE Primary Drug Name

    Drug Info:
    Drug Class antihypertensive agents
    Year of Approval 1981
    Drug Class diuretics

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antihypertensive agent
    Drug Class Small Molecule
    FDA Approval approved

    Publications:

    • Version: 09-Feb-2016

    Alternate Names:
    C6H8CLN7O Drug Synonym
    CHEMBL945 Drug Synonym
    AMILORIDE pubchem_primary_name

    Drug Info:

    Publications:

    • Version: 4.3.02 (25-August-2011)

    Alternate Names:
    AMIPRAZIDINE Drug Synonym
    AMILORIDUM Drug Synonym
    AMYLORIDE Drug Synonym

    Drug Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:
    AMILORIDE GuideToPharmacology Ligand Name
    135649936 PubChem Drug SID

    Drug Info:

    Publications:

    • Version: 27-September-2017

    Alternate Names:

    Drug Info:

    Publications: