• ALPRAZOLAM CHEMBL661 FDA Approved

    Alternate Names:

    Alprazolam
    Niravam
    Xanax
    Xanax Xr
    U-31889
    C227
    ZOLAM
    ALPROX
    CPD000149316
    PANISTAT
    ALPRAZOLAMUM [INN-LATIN]
    XANAX (TN)
    ZACETIN
    TAFIL
    ALPRONAX
    ALPRAZOLAM INTENSOL
    XANAGIS
    ALCELAM
    VALEANS
    A6551_FLUKA
    CASSADAN
    611026_FLUKA
    ALPRAZOLAM NU-PHARM BRAND
    ZOTRAN
    ALZOLAM
    XANOLAM
    ALPRAZOLAM NOVOPHARM BRAND
    ALPRAZOLAN
    ALZAM
    TUS 1
    BIDD:GT0475
    ANPRESS
    D-65MT
    611026_ALDRICH
    FRONTAL
    STACCATO-ALPRAZOLAM
    DB00404
    ALPRAZOLAM ORION BRAND
    ALPRAZOLAM EXTENDED RELEASE TABLETS
    ALPRAZOLAM APOTEX BRAND
    XANOR
    STK590494
    28981-97-7
    ALPRAZOLAMUM
    8-CHLORO-1-METHYL-6-PHENYL-4H-S-TRIAZOLO(4,3-ALPHA)(1,4)BENZODIAZEPINE
    ALPRAZOLAM (JP15/USP/INN)
    D00225
    TUS-1
    ZOLDAX
    ZANAPAM
    ALPRAZOLAM PFIZER BRAND
    APO ALPRAZ
    PFIZER BRAND OF ALPRAZOLAM
    ALZON
    ALPLAX
    4H-S-TRIAZOLO(4,3-A)(1,4)BENZODIAZEPINE, 8-CHLORO-1-METHYL-6-PHENYL-
    BESTROL
    EINECS 249-349-2
    ALPRAZOLAM SOLUTION
    CHEBI:2611
    DAP000239
    C06817
    TRANQUINAL
    PRAZAM
    ALPRAZOLAM ALPHAPHARM BRAND
    PRAZOLAN
    ORION BRAND OF ALPRAZOLAM
    ZOLAN
    I14-7472
    ALGAD
    TRANAX
    8-CHLORO-1-METHYL-6-(PHENYL-D5)-4H-(1,2,4)TRIAZOLO[4,3-A][1,4]BENZODIAZEPINE
    ESPARON
    ALPRAM
    MLS000559000
    APOTEX BRAND OF ALPRAZOLAM
    4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPINE, 8-CHLORO-1-METHYL-6-PHENYL-
    ZAXAN
    CONSTAN
    AZOR
    HELEX
    BIO-0790
    NEUROL
    CID2118
    ZOLDAC
    ALPRAZOLAM-D5
    ZOPIC
    RELAXOL
    HMS2051A10
    ALPHAPHARM BRAND OF ALPRAZOLAM
    AC-18721
    TAFIL D
    RESTYL
    DEA NO. 2882
    MIALIN
    TRANKIMAZIN
    NUALPRAZ
    XANAX TS
    ALPRAZOLAM KENRAL BRAND
    PANIX
    ZOPAX
    ZINC00000903
    NU-PHARM BRAND OF ALPRAZOLAM
    4H-(1,2,4)TRIAZOLO(4,3-A)(1,4)BENZODIAZEPINE, 8-CHLORO-1-METHYL-6-PHENYL-
    INTENSOL
    PHARNAX
    NOVO ALPRAZOL
    KENRAL BRAND OF ALPRAZOLAM
    ALPAZ
    NOVOALPRAZOL
    PRINOX
    ARZNEIMITTELWERK DRESDEN BRAND OF ALPRAZOLAM
    NOVOPHARM BRAND OF ALPRAZOLAM
    MOLPORT-002-507-836
    ZOLAREM
    SAM001246696
    BIDD:PXR0150
    TRICALMA
    SOLANAX
    NU PHARM BRAND OF ALPRAZOLAM
    GEN-ALPRAZOLAN
    AZ-002
    RALOZAM
    ALPRAZOLAM [USAN:INN:BAN:JAN]
    UNILAN
    NCGC00159466-03
    ALVIZ
    MLS000759485
    4H-(1,2,4)TRIAZOLO(4,3-ALPHA)(1,4)BENZODIAZEPINE, 8-CHLORO-1-METHYL-6-PHENYL-
    UNII-YU55MQ3IZY
    A8800_SIGMA
    2118
    NOVO-ALPRAZOL
    LS-156344
    NCHEMBIO747-COMP35
    TEMMLER BRAND OF ALPRAZOLAM
    ZENAX
    KSALOL
    NU ALPRAZ
    BRN 1223125
    D000525
    D 65MT
    176116
    HSDB 7207
    SMR000149316
    APOALPRAZ
    8-CHLORO-1-METHYL-6-PHENYL-4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPINE
    D65MT
    AP-1002
    TENSIVAN
    NCGC00159466-02
    NU-ALPRAZ
    TGAR01P
    AC1L1CYL
    AKOS005066050
    A6551_SIGMA
    ALPRAX
    ALPRAZOLAM TEMMLER BRAND
    APO-ALPRAZ
    2248706
    PA448333
    2034
    CC1NNC2N1-C3CCC(CC3C(=NC2)C4CCCCC4)CL
    46507078
    64980-140-06
    2611
    178103688
    7111
    ZB000199
    PL053252
    DR001286
    BC226242
    NSC-760140
    NC00105
    MCULE-1215564244
    CCG-100855
    ALPRAZOLAM [USAN:USP:INN:BAN:JAN]
    NSC760140
    BDBM50001728
    BBL028160
    TOX21_111692
    PHARMAKON1600-01502395
    HMS3393A10
    GTPL7111
    ALPRAZOLAM (JP16/USP/INN)
    MLS001423979
    ZINC903
    DSSTOX_GSID_22577
    DSSTOX_RID_76639
    SCHEMBL8398
    YU55MQ3IZY
    DSSTOX_CID_2577
    3U5J
    XANAXREG
    NIRAVAMREG
    VREFGVBLTWBCJP-UHFFFAOYSA-N
    51339-48-1
    12-CHLORO-3-METHYL-9-PHENYL-2,4,5,8-TETRAAZATRICYCLO[8.4.0.0?,?]TETRADECA-1(10),3,5,8,11,13-HEXAENE
    12-CHLORO-3-METHYL-9-PHENYL-2,4,5,8-TETRAAZATRICYCLO[8.4.0.0(2),?]TETRADECA-1(10),3,5,8,11,13-HEXAENE
    08H
    8-CHLORANYL-1-METHYL-6-PHENYL-4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPINE
    BRD-K32398298-001-01-4
    W-107015
    3B2-6502
    A819702
    FT-0658560
    CAS-28981-97-7
    135652428
    R396
    135652025
    BIM 23030
    (3S)-3-{[(1S)-3-CARBAMOYL-1-{[(1S)-1-{[(1S)-1-(CARBAMOYLMETHYLCARBAMOYL)-2-PHENYLETHYL]CARBAMOYL}-2-(1H-INDOL-3-YL)ETHYL]CARBAMOYL}PROPYL]CARBAMOYL}-3-[(2S)-2-ACETAMIDO-4-METHYLPENTANAMIDO]PROPANOIC ACID
    GLYCINAMIDE, N-ACETYL-L-LEUCYL-L-ALPHA-ASPARTYL-L-GLUTAMINYL-L-TRYPTOPHYL-L-PHENYLALANYL-
    ACETYLLEUCYL-ASPARTYL-GLUTAMINYL-TRYPTOPHYL-PHENYLALANYL-GLYCINE AMIDE
    AM014448
    ZINC150339575
    AR-1J1219
    AC-LEU-ASP-GLN-TRP-PHE-GLY-NH2
    GTPL2118
    ACLEU-ASP-GLN-TRP-PHE-GLYNH2
    AC1L4UJ1
    AC1Q5JAT
    129809-09-2
    (3S)-3-[[(2S)-2-ACETAMIDO-4-METHYLPENTANOYL]AMINO]-4-[[(2S)-5-AMINO-1-[[(2S)-1-[[(2S)-1-[(2-AMINO-2-OXOETHYL)AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]AMINO]-3-(1H-INDOL-3-YL)-1-OXOPROPAN-2-YL]AMINO]-1,5-DIOXOPENTAN-2-YL]AMINO]-4-OXOBUTANOIC ACID
    GLYCINAMIDE, N-ACETYL-L-LEUCYL-L-|A-ASPARTYL-L-GLUTAMINYL-L-TRYPTOPHYL-L-PHENYLALANYL-
    R-396
    164286
    R 396
    Xanax Ts Tab 2mg
    Xanax Tab 1mg
    Xanax Tab 0.5mg
    Xanax Tab 0.25mg
    Teva-alprazolam
    Sentrazolam Am
    Riva-alprazolam 0.5 mg
    Riva-alprazolam 0.25 mg
    Riva-alprazolam
    Ratio-alprazolam
    Nu-alpraz Tab 0.5mg
    Nu-alpraz Tab 0.25mg
    Ntp-alprazolam
    Nat-alprazolam
    Mylan-alprazolam
    Jamp-alprazolam
    Ipg-alprazolam
    Gabazolamine-0.5
    Gabazolamine
    Apo-alpraz Ts
    Apo-alpraz Tab 0.5mg
    Apo-alpraz Tab 0.25mg
    Alprazolam-1
    Alprazolam-0.5 Tab 0.5mg
    Alprazolam-0.25 Tab 0.25mg
    Alprazolam XR
    Alprazolam Ts
    Alprazolam Tablets 0.5mg
    Alprazolam Tablets 0.25
    Alprazolam Extended-release
    Alprazolam Extended Release
    Alprazolam ER
    CAS_117580-24-2
    57339667
    BDBM82456

    Drug Info:

    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications anxiolytic, sedative,hypnotic
    Drug Type drug/small molecule
    ATC n05ba(benzodiazepine derivatives)
    Drug Class anti-anxiety agents
    Year of Approval 1981
    Drug Categories tranquilizing agents
    Drug Categories therapeutic uses
    Drug Categories psychotropic drugs
    Drug Categories psycholeptics
    Drug Categories physiological effects of drugs
    Drug Categories pharmacologic actions
    Drug Categories neurotransmitter agents
    Drug Categories nervous system
    Drug Categories molecular mechanisms of pharmacological action
    Drug Categories hypnotics and sedatives
    Drug Categories heterocyclic compounds, 2-ring
    Drug Categories heterocyclic compounds
    Drug Categories gaba modulators
    Drug Categories gaba agents
    Drug Categories cytochrome p-450 cyp3a4 substrates
    Drug Categories cytochrome p-450 cyp3a4 inhibitors (weak)
    Drug Categories cytochrome p-450 cyp3a inhibitors
    Drug Categories cytochrome p-450 cyp2c9 substrates
    Drug Categories chemical actions and uses
    Drug Categories central nervous system depressants
    Drug Categories central nervous system agents
    Drug Categories benzodiazepines
    Drug Categories benzodiazepine derivatives
    Drug Categories benzazepines
    Drug Categories anti-anxiety agents
    Drug Groups investigational
    Drug Groups illicit
    Drug Groups approved
    Drug Type small molecule
    Drug Class hypnotics and sedatives
    (9 More Sources)
  • Interaction Types:
    allosteric modulator
    positive allosteric modulator

    Interaction Info:
    Specific Binding Site for Interaction benzodiazepine site
    Specific Action of the Ligand Positive
    Endogenous Drug? False

  • Interaction Types:
    allosteric modulator
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Specific Binding Site for Interaction benzodiazepine site

    Publications:

  • Interaction Types:
    allosteric modulator
    positive allosteric modulator

    Interaction Info:
    Specific Binding Site for Interaction benzodiazepine site
    Specific Action of the Ligand Positive
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    allosteric modulator
    positive allosteric modulator

    Interaction Info:
    Specific Binding Site for Interaction benzodiazepine site
    Specific Action of the Ligand Positive
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    antagonist

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    agonist

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name alprazolam,Xanax, Xanax XR
    Novel drug target Established target
    Trial Name AZ-002, Staccato alprazolam

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name AZ-002, Staccato alprazolam
    Novel drug target Established target
    Trial Name alprazolam,Xanax, Xanax XR

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name alprazolam,Xanax, Xanax XR

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name alprazolam,Xanax, Xanax XR
    Novel drug target Established target
    Trial Name AZ-002, Staccato alprazolam

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name alprazolam,Xanax, Xanax XR

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name alprazolam,Xanax, Xanax XR

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name alprazolam,Xanax, Xanax XR

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name alprazolam,Xanax, Xanax XR

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Trial Name alprazolam,Xanax, Xanax XR
    Novel drug target Established target
    Trial Name AZ-002, Staccato alprazolam

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Mechanism of Interaction GABA-A receptor; anion channel positive allosteric modulator
    Direct Interaction yes
    Trial Name alprazolam,Xanax, Xanax XR

    Publications:

  • Interaction Types:
    positive allosteric modulator

    Interaction Info:
    Direct Interaction yes
    Trial Name alprazolam,Xanax, Xanax XR
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name alprazolam,Xanax, Xanax XR
    Novel drug target Established target
    Trial Name AZ-002, Staccato alprazolam

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name AZ-002, Staccato alprazolam
    Novel drug target Established target

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:
    Trial Name alprazolam,Xanax, Xanax XR
    Novel drug target Established target
    Trial Name AZ-002, Staccato alprazolam

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    Publications:

  • Interaction Types:
    n/a

    Interaction Info:

    Publications: